PIPA595193
TSC1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA595193-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA595193 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
TSC1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
TSC1
Gene Alias
hamartin, HGNC:12362, Kiaa0243, LAM, MGC86987, OTTHUMP00000022439, OTTHUMP00000198378, TSC, Tsc1, tuberous sclerosis 1, tuberous sclerosis 1 protein, Tuberous sclerosis 1 protein homolog, tumor suppressor
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
60445, 7248
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Lyophilized
Applications
Western Blot
Concentration
500 μg/mL
Formulation
PBS with 5MG BSA and 0.05MG sodium azide
Gene Accession No.
Q92574, Q9Z136
Gene Symbols
TSC1
Immunogen
E.coli-derived human Hamartin recombinant protein (Position: D686-Y884).
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Human Hamartin shares 96% and 95% amino acid (aa) sequences identity with mouse and rat Hamartin, respectively
- Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL
- Tuberous sclerosis complex (TSC) is an autosomal dominant tumor syndrome caused by mutations in either of the TSC1 or TSC2 tumor suppressor genes
- The products of these genes form a protein complex that indirectly decreases the signaling of the mammalian Target of Rapamycin (TOR), an evolutionarily conserved serine/threonine kinase that regulates cell growth and cell cycle through its ability to integrate signals from nutrient levels and growth factors
- TOR activity is stimulated by Rheb, a member of the Ras superfamily of G-proteins, when the GTP/GDP ratio bound to Rheb is high
- Immunoprecipitated TSC1/TSC2 has been shown to stimulate Rheb GTPase activity in vitro, suggesting that the TSC1/TSC2 decreases the ability of Rheb to stimulate TOR activity
- This is supported by experiments showing overexpression of TSC1 and TSC2 results in a significant decrease in the GTP/GDP ratio bound to Rheb and the inhibition of cell growth
- A shorter 40 kDa isoform of TSC1 has been shown to exist but its function is unknown.
Compare Similar Items
Show Difference
Antigen: TSC1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TSC1
Gene Alias: hamartin, HGNC:12362, Kiaa0243, LAM, MGC86987, OTTHUMP00000022439, OTTHUMP00000198378, TSC, Tsc1, tuberous sclerosis 1, tuberous sclerosis 1 protein, Tuberous sclerosis 1 protein homolog, tumor suppressor
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 60445, 7248
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Lyophilized
Applications: Western Blot
Concentration: 500 μg/mL
Formulation: PBS with 5MG BSA and 0.05MG sodium azide
Gene Accession No.: Q92574, Q9Z136
Gene Symbols: TSC1
Immunogen: E.coli-derived human Hamartin recombinant protein (Position: D686-Y884).
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
TSC1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TSC1
Gene Alias:
hamartin, HGNC:12362, Kiaa0243, LAM, MGC86987, OTTHUMP00000022439, OTTHUMP00000198378, TSC, Tsc1, tuberous sclerosis 1, tuberous sclerosis 1 protein, Tuberous sclerosis 1 protein homolog, tumor suppressor
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
60445, 7248
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Lyophilized
Applications:
Western Blot
Concentration:
500 μg/mL
Formulation:
PBS with 5MG BSA and 0.05MG sodium azide
Gene Accession No.:
Q92574, Q9Z136
Gene Symbols:
TSC1
Immunogen:
E.coli-derived human Hamartin recombinant protein (Position: D686-Y884).
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: TSC2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TSC2
Gene Alias: LAM, Nafld, OTTHUMP00000198394, PPP1R160, protein phosphatase 1, regulatory subunit 160, Rc, renal carcinoma, Tcs2, Tsc2, TSC4, Tuberin, tuberous sclerosis 2, tuberous sclerosis 2 homolog protein, tuberous sclerosis 2 protein, Tuberous sclerosis 2 protein homolog
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 22084, 24855, 7249
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Lyophilized
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 500 μg/mL
Formulation: PBS with 5MG BSA and 0.05MG sodium azide
Gene Accession No.: P49815, P49816, Q61037
Gene Symbols: TSC2
Immunogen: E.coli-derived human Tuberin recombinant protein (Position: H1611-V1807).
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
TSC2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TSC2
Gene Alias:
LAM, Nafld, OTTHUMP00000198394, PPP1R160, protein phosphatase 1, regulatory subunit 160, Rc, renal carcinoma, Tcs2, Tsc2, TSC4, Tuberin, tuberous sclerosis 2, tuberous sclerosis 2 homolog protein, tuberous sclerosis 2 protein, Tuberous sclerosis 2 protein homolog
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
22084, 24855, 7249
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Lyophilized
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
500 μg/mL
Formulation:
PBS with 5MG BSA and 0.05MG sodium azide
Gene Accession No.:
P49815, P49816, Q61037
Gene Symbols:
TSC2
Immunogen:
E.coli-derived human Tuberin recombinant protein (Position: H1611-V1807).
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Ubiquitin B
Classification: Polyclonal
Conjugate: Unconjugated
Gene: UBB
Gene Alias: AL033289, epididymis secretory protein Li 50, HEL-S-50, HUBCEP52, im:6892314, im:6892314 protein, MGC127041, polyubiquitin, polyubiquitin B, polyubiquitin-B, RPL40, Rps27a, si:ch211-202a12.3, Uba52, Ubb, Ubb2, UBC, Ubi-p63E, Ubiquitin, ubiquitin B, ubiquitin C, Ubiquitin-related, zgc:172187, zUBC
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 192255, 22187, 7314
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Lyophilized
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 500 μg/mL
Formulation: PBS with 5MG BSA and 0.05MG sodium azide
Gene Accession No.: P0CG47, P0CG49, P0CG51
Gene Symbols: UBB
Immunogen: E.coli-derived human Ubiquitin recombinant protein (Position: M77-G152).
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Ubiquitin B
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
UBB
Gene Alias:
AL033289, epididymis secretory protein Li 50, HEL-S-50, HUBCEP52, im:6892314, im:6892314 protein, MGC127041, polyubiquitin, polyubiquitin B, polyubiquitin-B, RPL40, Rps27a, si:ch211-202a12.3, Uba52, Ubb, Ubb2, UBC, Ubi-p63E, Ubiquitin, ubiquitin B, ubiquitin C, Ubiquitin-related, zgc:172187, zUBC
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
192255, 22187, 7314
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Lyophilized
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
500 μg/mL
Formulation:
PBS with 5MG BSA and 0.05MG sodium azide
Gene Accession No.:
P0CG47, P0CG49, P0CG51
Gene Symbols:
UBB
Immunogen:
E.coli-derived human Ubiquitin recombinant protein (Position: M77-G152).
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: BMI-1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: BMI1
Gene Alias: AW546694, B lymphoma Mo-MLV insertion region 1, B lymphoma Mo-MLV insertion region 1 homolog, Bmi1, Bmi-1, BMI1 polycomb ring finger oncogene, BMI1 polycomb ring finger proto-oncogene, BMI1 proto-oncogene, polycomb ring finger, FLVI2/BMI1, flvi-2/bmi-1, murine leukemia viral (bmi-1) oncogene homolog, Pcgf4, Pcgf4 antibody, Polycomb complex protein BMI-1, polycomb group protein Bmi1, polycomb group ring finger 4, polycomb group RING finger protein 4, RING finger protein 51, RNF51, RP11-573G6.1
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 12151, 307151, 648
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Lyophilized
Applications: Western Blot
Concentration: 500 μg/mL
Formulation: PBS with 5MG BSA and 0.05MG sodium azide
Gene Accession No.: P25916, P35226
Gene Symbols: BMI1
Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human Bmi1 (135-165aa IEFFDQNRLDRKVNKDKEKSKEEVNDKRYLR).
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
BMI-1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
BMI1
Gene Alias:
AW546694, B lymphoma Mo-MLV insertion region 1, B lymphoma Mo-MLV insertion region 1 homolog, Bmi1, Bmi-1, BMI1 polycomb ring finger oncogene, BMI1 polycomb ring finger proto-oncogene, BMI1 proto-oncogene, polycomb ring finger, FLVI2/BMI1, flvi-2/bmi-1, murine leukemia viral (bmi-1) oncogene homolog, Pcgf4, Pcgf4 antibody, Polycomb complex protein BMI-1, polycomb group protein Bmi1, polycomb group ring finger 4, polycomb group RING finger protein 4, RING finger protein 51, RNF51, RP11-573G6.1
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
12151, 307151, 648
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Lyophilized
Applications:
Western Blot
Concentration:
500 μg/mL
Formulation:
PBS with 5MG BSA and 0.05MG sodium azide
Gene Accession No.:
P25916, P35226
Gene Symbols:
BMI1
Immunogen:
A synthetic peptide corresponding to a sequence in the middle region of human Bmi1 (135-165aa IEFFDQNRLDRKVNKDKEKSKEEVNDKRYLR).
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG