PIPA590594
ATM Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA590594-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA590594 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
ATM
Classification
Polyclonal
Conjugate
Unconjugated
Gene
ATM
Gene Alias
AI256621, AT mutated, A-T mutated, A-T mutated homolog, AT mutated protein, AT1, ATA, Ataxia t, Ataxia telangiectasia gene mutated in human beings, ataxia telangiectasia mutated, Ataxia telangiectasia mutated homolog, ATC, ATD, ATDC, ATE, Atm, ATM (phospho S1981), ATM (pS1981), ATM (pSer1981), ATM phospho S1981, ATM phospho Ser1981, ATM serine/threonine kinase, C030026E19Rik, DKFZp781A0353, EC 2.7.1.37, MGC74674, phospho ATM, phospho S1981 ATM, serine-protein kinase ATM, TEL1, TEL1, telomere maintenance 1, homolog, TELO1
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
300711, 472
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry
Concentration
0.71 mg/mL
Formulation
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.
Q13315
Gene Symbols
ATM
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 2320-2566 of ATM (NP_0000423)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: DASCAANNPS LKLTYTECLR VCGNWLAETC LENPAVIMQT YLEKAVEVAG NYDGESSDEL RNGKMKAFLS LARFSDTQYQ RIENYMKSSE FENKQALLKR AKEEVGLLRE HKIQTNRYTV KVQRELELDE LALRALKEDR KRFLCKAVEN YINCLLSGEE HDMWVFRLCS LWLENSGVSE VNGMMKRDGM KIPTYKFLPL MYQLAARMGT KMMGGLGFHE VLNNLISRIS MDHPHHTLFI ILALANA Positive Samples: Cellular Location: Cytoplasmic vesicle, Nucleus Ataxia-telangiectasia Mutated (ATM) is a protein that belongs to the PI3/PI4 kinase family
- Ataxia-telangiectasia is a rare autosomal recessive disorder characterized by progressive neurologic degeneration, immunologic deficiency, and an increased risk of lymphoid cancer
- The ATM gene codes for a protein belonging to the phosphoinositide 3-kinase (PI3K) superfamily
- ATM phosphorylates proteins instead of lipid and has many downstream targets that act as cell-cycle regulators including: P53, Mdm2, BRCA1, and SMC1
- The ATM protein is responsible for repairing double-stranded DNA breaks that occur because of ionizing radiation and other mutagens
- The ATM’s C-terminal region has extensive homology to the catalytic domains of phosphatidylinositol 3-kinases (PI3 kinases)
- Studies have shown that ATM becomes autophosphorylated and upregulated by exposure to ionizing radiation
- AT cells are hypersensitive to ionizing radiation, impaired in mediating the inhibition of DNA synthesis and display delays in p53 induction
- Further, DNA damage caused by ionizing irradiation activates ATM-kinase, leading to a cascade of kinase reactions that regulate cell cycle, apoptosis, and DNA damage repair
- Studies have linked ATM to apoptosis along with Nbs1 and Chk2 in the E2F1 pathway.
Compare Similar Items
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Antigen: ATM
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ATM
Gene Alias: AI256621, AT mutated, A-T mutated, A-T mutated homolog, AT mutated protein, AT1, ATA, Ataxia t, Ataxia telangiectasia gene mutated in human beings, ataxia telangiectasia mutated, Ataxia telangiectasia mutated homolog, ATC, ATD, ATDC, ATE, Atm, ATM (phospho S1981), ATM (pS1981), ATM (pSer1981), ATM phospho S1981, ATM phospho Ser1981, ATM serine/threonine kinase, C030026E19Rik, DKFZp781A0353, EC 2.7.1.37, MGC74674, phospho ATM, phospho S1981 ATM, serine-protein kinase ATM, TEL1, TEL1, telomere maintenance 1, homolog, TELO1
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 300711, 472
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry
Concentration: 0.71 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.: Q13315
Gene Symbols: ATM
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 2320-2566 of ATM (NP_0000423)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
ATM
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ATM
Gene Alias:
AI256621, AT mutated, A-T mutated, A-T mutated homolog, AT mutated protein, AT1, ATA, Ataxia t, Ataxia telangiectasia gene mutated in human beings, ataxia telangiectasia mutated, Ataxia telangiectasia mutated homolog, ATC, ATD, ATDC, ATE, Atm, ATM (phospho S1981), ATM (pS1981), ATM (pSer1981), ATM phospho S1981, ATM phospho Ser1981, ATM serine/threonine kinase, C030026E19Rik, DKFZp781A0353, EC 2.7.1.37, MGC74674, phospho ATM, phospho S1981 ATM, serine-protein kinase ATM, TEL1, TEL1, telomere maintenance 1, homolog, TELO1
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
300711, 472
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry
Concentration:
0.71 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.:
Q13315
Gene Symbols:
ATM
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 2320-2566 of ATM (NP_0000423)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: VPS51
Classification: Polyclonal
Conjugate: Unconjugated
Gene: VPS51
Gene Alias: 1110014N23Rik, 3110057M17Rik, AI837850, ANG2, ANG3, Another new gene 2 protein, C11orf2, C11orf3, Ffr, PP5382, Protein fat-free homolog, vacuolar protein sorting 51 homolog, vacuolar protein sorting 51 homolog (S. cerevisiae), vacuolar protein sorting-associated protein 51 homolog, VPS51, VPS51 GARP complex subunit, VPS51, GARP complex subunit
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 738
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 1.55 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.: Q9UID3
Gene Symbols: VPS51
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human VPS51 (NP_0373972)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
VPS51
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
VPS51
Gene Alias:
1110014N23Rik, 3110057M17Rik, AI837850, ANG2, ANG3, Another new gene 2 protein, C11orf2, C11orf3, Ffr, PP5382, Protein fat-free homolog, vacuolar protein sorting 51 homolog, vacuolar protein sorting 51 homolog (S. cerevisiae), vacuolar protein sorting-associated protein 51 homolog, VPS51, VPS51 GARP complex subunit, VPS51, GARP complex subunit
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
738
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
1.55 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.:
Q9UID3
Gene Symbols:
VPS51
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human VPS51 (NP_0373972)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: Cdc20
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CDC20
Gene Alias: 2310042N09Rik, bA276H19.3, C87100, cdc20, CDC20 cell division cycle 20 homolog, cdc20.S, CDC20A, cell cycle protein p55CDC, cell division cycle 20, cell division cycle 20 homolog, cell division cycle 20 S homeolog, cell division cycle protein 20 homolog, fizzy1, mmCdc20, p55cdc, XELAEV_18025163mg, X-FZY
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 107995, 64515, 991
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration: 1.172 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.: Q12834, Q62623, Q9JJ66
Gene Symbols: CDC20
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human CDC20 (NP_0012462?)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Cdc20
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CDC20
Gene Alias:
2310042N09Rik, bA276H19.3, C87100, cdc20, CDC20 cell division cycle 20 homolog, cdc20.S, CDC20A, cell cycle protein p55CDC, cell division cycle 20, cell division cycle 20 homolog, cell division cycle 20 S homeolog, cell division cycle protein 20 homolog, fizzy1, mmCdc20, p55cdc, XELAEV_18025163mg, X-FZY
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
107995, 64515, 991
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration:
1.172 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.:
Q12834, Q62623, Q9JJ66
Gene Symbols:
CDC20
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human CDC20 (NP_0012462?)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: ETS1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ETS1
Gene Alias: AI196000, AI448617, Avian erythroblastosis virus E26 (v-ets) oncogene homolog-1, avian erythroblastosis virus E26 oncogene 1, c-ets protein, c-ets1, c-ets-1, c-ets-1 oncogene, c-ets-1 protein, c-ets-alpha, c-ets-beta, D230050P06, E26 avian leukemia oncogene 1, 5' domain, Ets avian erythroblastosis virus E2 oncogene homolog 1 (tumor progression locus 1), ets protein, ETS proto-oncogene 1, transcription factor, Ets1, ETS-1, ETS-1A, ETS-1B, Ets-1Delta(III-VI), Etsoncb, EWSR2, FLJ10768, oncoprotein, p54, p54 transcription factor, protein C-ets-1, TNFAIP3 interacting protein 1, TNIP1, Tpl1, transforming protein p54/c-ets-1, transforming protein p68/c-ets-1, tumor progression locus 1, unnamed protein product, v-ets avian erythroblastosis virus E2 oncogene homolog 1, v-ets avian erythroblastosis virus E26 oncogene homolog 1, v-ets erythroblastosis virus E26 oncogene homolog 1, virion-associated nuclear-shuttling protein
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 2113, 23871, 24356
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 1.98 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.: P14921, P27577, P41156
Gene Symbols: ETS1
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 342-441 of human ETS1 (NP_0052291)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
ETS1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ETS1
Gene Alias:
AI196000, AI448617, Avian erythroblastosis virus E26 (v-ets) oncogene homolog-1, avian erythroblastosis virus E26 oncogene 1, c-ets protein, c-ets1, c-ets-1, c-ets-1 oncogene, c-ets-1 protein, c-ets-alpha, c-ets-beta, D230050P06, E26 avian leukemia oncogene 1, 5' domain, Ets avian erythroblastosis virus E2 oncogene homolog 1 (tumor progression locus 1), ets protein, ETS proto-oncogene 1, transcription factor, Ets1, ETS-1, ETS-1A, ETS-1B, Ets-1Delta(III-VI), Etsoncb, EWSR2, FLJ10768, oncoprotein, p54, p54 transcription factor, protein C-ets-1, TNFAIP3 interacting protein 1, TNIP1, Tpl1, transforming protein p54/c-ets-1, transforming protein p68/c-ets-1, tumor progression locus 1, unnamed protein product, v-ets avian erythroblastosis virus E2 oncogene homolog 1, v-ets avian erythroblastosis virus E26 oncogene homolog 1, v-ets erythroblastosis virus E26 oncogene homolog 1, virion-associated nuclear-shuttling protein
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
2113, 23871, 24356
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
1.98 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.:
P14921, P27577, P41156
Gene Symbols:
ETS1
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 342-441 of human ETS1 (NP_0052291)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG