PIPA594969

PSEN2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA594969-Each-of-1 In Stock ₹ 44,705.10

PIPA594969 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

PSEN2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

PSEN2

Gene Alias

AD3L, AD3LP, AD4, Ad4h, AD5, Alg3, ALG-3, Alzheimer disease 4, CMD1V, E5-1, presenilin 2, presenilin-2, Presenilin-2 CTF subunit, Presenilin-2 NTF subunit, PS2, Ps-2, PSEN 2, PSEN2, Psnl2, STM2, STM-2

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

19165, 5664, 81751

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Lyophilized

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

500 μg/mL

Formulation

PBS with 5MG BSA and 0.05MG sodium azide, 0.05MG thimerosal

Gene Accession No.

O88777, P49810, Q61144

Gene Symbols

PSEN2

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of human Presenilin 2 (39-51aa EDGENTAQWRSQE).

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL
  • Alzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1 or PSEN2) or the amyloid precursor protein (APP)
  • These disease-linked mutations result in increased production of the longer form of amyloid-beta (main component of amyloid deposits found in AD brains)
  • Presenilins are postulated to regulate APP processing through their effects on gamma-secretase, an enzyme that cleaves APP
  • Also, it is thought that the presenilins are involved in the cleavage of the Notch receptor such that, they either directly regulate gamma-secretase activity, or themselves act are protease enzymes
  • Two alternatively spliced transcript variants encoding different isoforms of PSEN2 have been identified.

Compare Similar Items

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Img

Thermo Scientific

PIPA594969

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Antigen:
PSEN2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PSEN2

Gene Alias:
AD3L, AD3LP, AD4, Ad4h, AD5, Alg3, ALG-3, Alzheimer disease 4, CMD1V, E5-1, presenilin 2, presenilin-2, Presenilin-2 CTF subunit, Presenilin-2 NTF subunit, PS2, Ps-2, PSEN 2, PSEN2, Psnl2, STM2, STM-2

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
19165, 5664, 81751

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 5MG BSA and 0.05MG sodium azide, 0.05MG thimerosal

Gene Accession No.:
O88777, P49810, Q61144

Gene Symbols:
PSEN2

Immunogen:
A synthetic peptide corresponding to a sequence at the N-terminus of human Presenilin 2 (39-51aa EDGENTAQWRSQE).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA594971

--


Antigen:
Human TNF beta

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
LTA

Gene Alias:
DAMA-25N12.13, hlb382, hypothetical protein, LT, LT[a], LT-[a], LTA, LTalpha, LT-alpha, Ltx, lymphotoxin A, lymphotoxin alpha, lymphotoxin alpha (TNF superfamily, member 1), lymphotoxin-alpha, lymphotoxin-alpha, lymphotoxin alpha, TNF b, TNF beta, TNF superfamily, member 1, TNF β, Tnfb, TNFbeta, TNF-beta, TNF-N, Tnfsf1, Tnfsf1b, TNFβ, TNLG1E, tumor necrosis factor beta, tumor necrosis factor ligand 1E, tumor necrosis factor ligand superfamily member 1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4049

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Lyophilized

Applications:
Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 5MG BSA and 0.05MG sodium azide, 0.05MG thimerosal

Gene Accession No.:
P01374

Gene Symbols:
LTA

Immunogen:
A synthetic peptide corresponding to a sequence at the N-terminus of human TNF beta (45-59aa AQTARQHPKMHLAHS).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA594972

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Antigen:
MEK1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Map2k1

Gene Alias:
CFC3, dual specificity mitogen activated protein kinase kinase 1, dual specificity mitogen-activated protein kinase kinase 1, EC 2.7.12.2, ERK activator kinase 1, kinase MEK1, MAP kinase kinase 1, MAP kinase kinase or Erk Kinase, Dual specificity mitogen-activated protein kinase kinase, involved in ras mediated vulval induction, LEThal LET-537 (42.8 kD) (mek-2), MAP kinase/Erk kinase 1, Map2k1, map2k1.L, MAPK/ERK kinase 1, MAPKK 1, MAPKK1, MEK 1, Mek1, MEK2, mek-2, MEKK1, mitogen activated protein kinase kinase 1, mitogen-activated protein kinase kinase 1, mitogen-activated protein kinase kinase 1 L homeolog, MKK (Thr292), MKK (Thr386), MKK1, MKK2, MP2K1, Prkmk1, PRKMK2, protein kinase, mitogen activated, kinase 1, p45, protein kinase, mitogen-activated, kinase 1 (MAP kinase kinase 1), XELAEV_18018447mg

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
170851, 26395, 5604

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Lyophilized

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 5MG BSA and 0.05MG sodium azide, 0.05MG thimerosal

Gene Accession No.:
P31938, Q01986, Q02750

Gene Symbols:
Map2k1

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human MEK1 (353-367aa KQLMVHAFIKRSDAE).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA594973

--


Antigen:
MEK3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MAP2K3

Gene Alias:
AW212142, dual specificity mitogen-activated protein kinase kinase 3, EC 2.7.12.2, MAP kinase kinase 3, Map2k3, MAPK/ERK kinase 3, MAPKK 3, MAPKK3, MEK 3, Mek3, mitogen activated protein kinase kinase 3, mitogen-activated protein kinase kinase 3, Mkk3, mMKK3b, Prkmk3, protein kinase, mitogen-activated, kinase 3, SAPK kinase 2, SAPKK2, SAPKK-2, SKK2, Stress-activated protein kinase kinase 2

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
26397, 303200, 5606

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Lyophilized

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 5MG BSA and 0.05MG sodium azide, 0.05MG thimerosal

Gene Accession No.:
O09110, P46734

Gene Symbols:
MAP2K3

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human MEK3 (320-334aa MEHPFFTLHKTKKTD).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG