PIPA594953

Cullin 4B Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA594953-Each-of-1 In Stock ₹ 44,705.10

PIPA594953 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

Cullin 4B

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CUL4B

Gene Alias

2700050M05Rik, AA409770, CUL4B, CUL-4B, cullin 4B, cullin-4B, EGK_20888, KIAA0695, mKIAA0695, MRXHF2, MRXS15, MRXSC, RGD1564494, SFM2

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

302502, 560313, 72584, 8450

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Lyophilized

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

500 μg/mL

Formulation

PBS with 5MG BSA and 0.05MG sodium azide, 0.05MG thimerosal

Gene Accession No.

A2A432, Q13620

Gene Symbols

CUL4B

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human Cullin 4B (895-913aa DRDYMERDKENPNQYNYIA).

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat, Zebrafish

Product Type

Antibody

Isotype

IgG

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Description

  • Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL
  • Core component of multiple cullin-RING-based E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins
  • The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition subunit
  • CUL4B may act within the complex as a scaffold protein, contributing to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme
  • Plays a role as part of the E3 ubiquitin-protein ligase complex in polyubiquitination of CDT1, histone H2A, histone H3 and histone H4 in response to radiation-induced DNA damage
  • Targeted to UV damaged chromatin by DDB2 and may be important for DNA repair and DNA replication
  • Required for ubiquitination of cyclin E, and consequently, normal G1 cell cycle progression
  • Regulates the mammalian target-of-rapamycin (mTOR) pathway involved in control of cell growth, size and metabolism
  • Specific CUL4B regulation of the mTORC1-mediated pathway is dependent upon 26S proteasome function and requires interaction between CUL4B and MLST8.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA594953

--


Antigen:
Cullin 4B

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CUL4B

Gene Alias:
2700050M05Rik, AA409770, CUL4B, CUL-4B, cullin 4B, cullin-4B, EGK_20888, KIAA0695, mKIAA0695, MRXHF2, MRXS15, MRXSC, RGD1564494, SFM2

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
302502, 560313, 72584, 8450

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 5MG BSA and 0.05MG sodium azide, 0.05MG thimerosal

Gene Accession No.:
A2A432, Q13620

Gene Symbols:
CUL4B

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human Cullin 4B (895-913aa DRDYMERDKENPNQYNYIA).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat, Zebrafish

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA594956

--


Antigen:
Caspase 8 p18

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Casp8

Gene Alias:
ALPS2B, apoptotic cysteine protease, Apoptotic protease Mch-5, CAP4, Casp8, CASP-8, caspase 8, caspase 8, apoptosis-related cysteine peptidase, caspase 8, apoptosis-related cysteine protease, caspase-8, Caspase-8 subunit p10, Caspase-8 subunit p18, FADD-homologous ICE/ced-3-like protease, FADD-like ICE, Fas-linked ICE-like protease, FLICE, ICE-like apoptotic protease 5, MACH, MACH-alpha-1/2/3 protein, MACH-beta-1/2/3/4 protein, MCH5, MORT1-associated ced-3 homolog

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12370, 64044, 841

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Lyophilized

Applications:
Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 5MG BSA and 0.05MG sodium azide, 0.05MG thimerosal

Gene Accession No.:
O89110, Q14790, Q9JHX4

Gene Symbols:
Casp8

Immunogen:
A synthetic peptide corresponding to a sequence in the middle region of human Caspase-8 (P18) (240-259aa DKVYQMKSKPRGYCLIINNH).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA594957

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Antigen:
Phospholamban

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PLN

Gene Alias:
cardiac CMH18, Cardiac phospholamban, CMD1P, CMH18, phospholamban, Plb, Plm, PLN, unnamed protein product

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5350, 64672

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Lyophilized

Applications:
Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 5MG BSA and 0.05MG sodium azide, 0.05MG thimerosal

Gene Accession No.:
P26678, P61016

Gene Symbols:
PLN

Immunogen:
A synthetic peptide corresponding to a sequence at the N-terminus of human PLN (2-16aa EKVQYLTRSAIRRAS).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA594958

--


Antigen:
SNAP25

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Snap25

Gene Alias:
ALMS1, bA416N4.2, Bdr, blind drunk, CG17676, CG17884, CG40452, CMS18, dJ1068F16.2, Dmel CG40452, Dmel_CG40452, etID17571.20, etID69167.20, fj42b02, fj45g04, fj48c02, FLJ23079, GENA70, HGNC:11132, resistance to inhibitors of cholinesterase 4 homolog, RIC4, RIC-4, SEC9, si:dkeyp-8f4.6, Snap, SNAP 25, snap25, SNAP-25, snap25.1, SNAP-25.1, snap25a, SNAP-25A, SNAP-25B, snp25, sp, SUP, super protein, synaptosomal associated protein-25, synaptosomal-associated 25 kDa protein, Synaptosomal-associated protein 25, synaptosomal-associated protein 25-A, synaptosomal-associated protein, 25 kDa, synaptosomal-associated protein, 25a, synaptosomal-associated protein, 25kDa, synaptosome associated protein 25, synaptosome associated protein 25a, synaptosome associated protein 25kDa, synaptosome-associated protein 25.1, synaptosome-associated protein 25a, wu:fj42b02, wu:fj45g04, wu:fj48c02

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20614, 25012, 6616

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 5MG BSA and 0.05MG sodium azide, 0.05MG thimerosal

Gene Accession No.:
P60879, P60880, P60881

Gene Symbols:
Snap25

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human SNAP25 (186-200aa DSNKTRIDEANQRAT).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG