PIPA595164
MERTK Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA595164-Each-of-1 | In Stock | ₹ 44,277.30 |
PIPA595164 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,277.30
GST (18%): ₹ 7,969.914
Total Price: ₹ 52,247.214
Antigen
MERTK
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Mertk
Gene Alias
c-Eyk, c-mer, c-mer proto-oncogene tyrosine kinase, Eyk, MER, MER proto-oncogene, tyrosine kinase, MER receptor tyrosine kinase, MERTK, MGC133349, nmf12, Nyk, Proto-oncogene c-Mer, proto-oncogene tyrosine-protein kinase MER, rdy, receptor tyrosine kinase MerTK, Receptor tyrosine tinase gene probably the gene for Rdy, retinal dystrophy, RP38, sMER, sMERTK, soluble MER, soluble MERTK, STK kinase, Tyro 12, Tyro12, Tyrosine-protein kinase Mer
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
10461, 17289, 65037
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Lyophilized
Applications
Flow Cytometry, Western Blot
Concentration
500 μg/mL
Formulation
PBS with 4MG trehalose and 0.05MG sodium azide
Gene Accession No.
P57097, Q12866, Q60805
Gene Symbols
Mertk
Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of human MERTK (132-148aa KDGKELLGAHHAITQFY).
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse, Non-human Primate, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL
- MERTK (cMER) is a tyrosine kinase proto-oncogene and is involved in the retinal pigment epithelium (RPE) phagocytosis pathway, which is implicated in human retinal disease
- Regulates many physiological processes including cell survival, migration, differentiation, and phagocytosis of apoptotic cells (efferocytosis)
- Ligand binding at the cell surface induces autophosphorylation of MERTK on its intracellular domain that provides docking sites for downstream signaling molecules
- Following activation by ligand, interacts with GRB2 or PLCG2 and induces phosphorylation of MAPK1, MAPK2, FAK/PTK2 or RAC1
- MERTK signaling plays a role in various processes such as macrophage clearance of apoptotic cells, platelet aggregation, cytoskeleton reorganization and engulfment
- Functions in the retinal pigment epithelium (RPE) as a regulator of rod outer segments fragments phagocytosis
- Plays also an important role in inhibition of Toll-like receptors (TLRs)-mediated innate immune response by activating STAT1, which selectively induces production of suppressors of cytokine signaling SOCS1 and SOCS3.
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Antigen: MERTK
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Mertk
Gene Alias: c-Eyk, c-mer, c-mer proto-oncogene tyrosine kinase, Eyk, MER, MER proto-oncogene, tyrosine kinase, MER receptor tyrosine kinase, MERTK, MGC133349, nmf12, Nyk, Proto-oncogene c-Mer, proto-oncogene tyrosine-protein kinase MER, rdy, receptor tyrosine kinase MerTK, Receptor tyrosine tinase gene probably the gene for Rdy, retinal dystrophy, RP38, sMER, sMERTK, soluble MER, soluble MERTK, STK kinase, Tyro 12, Tyro12, Tyrosine-protein kinase Mer
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 10461, 17289, 65037
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Lyophilized
Applications: Flow Cytometry, Western Blot
Concentration: 500 μg/mL
Formulation: PBS with 4MG trehalose and 0.05MG sodium azide
Gene Accession No.: P57097, Q12866, Q60805
Gene Symbols: Mertk
Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human MERTK (132-148aa KDGKELLGAHHAITQFY).
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Non-human Primate, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
MERTK
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Mertk
Gene Alias:
c-Eyk, c-mer, c-mer proto-oncogene tyrosine kinase, Eyk, MER, MER proto-oncogene, tyrosine kinase, MER receptor tyrosine kinase, MERTK, MGC133349, nmf12, Nyk, Proto-oncogene c-Mer, proto-oncogene tyrosine-protein kinase MER, rdy, receptor tyrosine kinase MerTK, Receptor tyrosine tinase gene probably the gene for Rdy, retinal dystrophy, RP38, sMER, sMERTK, soluble MER, soluble MERTK, STK kinase, Tyro 12, Tyro12, Tyrosine-protein kinase Mer
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
10461, 17289, 65037
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Lyophilized
Applications:
Flow Cytometry, Western Blot
Concentration:
500 μg/mL
Formulation:
PBS with 4MG trehalose and 0.05MG sodium azide
Gene Accession No.:
P57097, Q12866, Q60805
Gene Symbols:
Mertk
Immunogen:
A synthetic peptide corresponding to a sequence at the N-terminus of human MERTK (132-148aa KDGKELLGAHHAITQFY).
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Non-human Primate, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: PKP2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PKP2
Gene Alias: 1200008D14Rik, 1200012P04Rik, AA516617, ARVD9, PKP2, Pkp2l, plakophilin 2, plakophilin-2
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 287925, 5318
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Lyophilized
Applications: Western Blot
Concentration: 500 μg/mL
Formulation: PBS with 5MG BSA and 0.05MG sodium azide, 0.05MG thimerosal
Gene Accession No.: Q99959
Gene Symbols: PKP2
Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Plakophilin 2 (863-881aa KKTDFVNSRTAKAYHSLKD).
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
PKP2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PKP2
Gene Alias:
1200008D14Rik, 1200012P04Rik, AA516617, ARVD9, PKP2, Pkp2l, plakophilin 2, plakophilin-2
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
287925, 5318
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Lyophilized
Applications:
Western Blot
Concentration:
500 μg/mL
Formulation:
PBS with 5MG BSA and 0.05MG sodium azide, 0.05MG thimerosal
Gene Accession No.:
Q99959
Gene Symbols:
PKP2
Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human Plakophilin 2 (863-881aa KKTDFVNSRTAKAYHSLKD).
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: CaV1.3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CACNA1D
Gene Alias: 8430418G19Rik, brain class D, C79217, Cach3, Cacn4, CACNA 1D, CACNA1D, Cacnl1a2, calcium channel alpha-1 subunit, Calcium channel, L type, alpha-1 polypeptide isoform 2, Calcium channel, L type, alpha-1 polypeptide, isoform 2, calcium channel, neuroendocrine/brain-type, alpha 1 subunit, calcium channel, voltage-dependent, L type, alpha 1D subunit, calcium voltage-gated channel subunit alpha1 D, Cav1.3, CaV1.3alpha1, Cchl1a, CCHL1A2, D-LTCC, PASNA, Rat brain class D, RBD, SANDD, voltage-dependent calcium channel subunit alpha1D, voltage-dependent L-type calcium channel subunit alpha-1D, voltage-gated calcium channel alpha 1 subunit, voltage-gated calcium channel alpha subunit Cav1.3, voltage-gated calcium channel pore forming subunit CaV1.3alpha1 IVS3-IVS4 extracellular linker, voltage-gated calcium channel subunit alpha Cav1.3
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 12289, 29716, 776
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Lyophilized
Applications: Western Blot
Concentration: 500 μg/mL
Formulation: PBS with 5MG BSA and 0.05MG sodium azide, 0.05MG thimerosal
Gene Accession No.: P27732, Q01668, Q99246
Gene Symbols: CACNA1D
Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human CaV1.3 (2146-2161aa RDEEDLADEMICITTL).
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
CaV1.3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CACNA1D
Gene Alias:
8430418G19Rik, brain class D, C79217, Cach3, Cacn4, CACNA 1D, CACNA1D, Cacnl1a2, calcium channel alpha-1 subunit, Calcium channel, L type, alpha-1 polypeptide isoform 2, Calcium channel, L type, alpha-1 polypeptide, isoform 2, calcium channel, neuroendocrine/brain-type, alpha 1 subunit, calcium channel, voltage-dependent, L type, alpha 1D subunit, calcium voltage-gated channel subunit alpha1 D, Cav1.3, CaV1.3alpha1, Cchl1a, CCHL1A2, D-LTCC, PASNA, Rat brain class D, RBD, SANDD, voltage-dependent calcium channel subunit alpha1D, voltage-dependent L-type calcium channel subunit alpha-1D, voltage-gated calcium channel alpha 1 subunit, voltage-gated calcium channel alpha subunit Cav1.3, voltage-gated calcium channel pore forming subunit CaV1.3alpha1 IVS3-IVS4 extracellular linker, voltage-gated calcium channel subunit alpha Cav1.3
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
12289, 29716, 776
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Lyophilized
Applications:
Western Blot
Concentration:
500 μg/mL
Formulation:
PBS with 5MG BSA and 0.05MG sodium azide, 0.05MG thimerosal
Gene Accession No.:
P27732, Q01668, Q99246
Gene Symbols:
CACNA1D
Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human CaV1.3 (2146-2161aa RDEEDLADEMICITTL).
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: KV1.1 (KCNA1)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Kcna1
Gene Alias: AEMK, AI840627, brain potassium channel protein-1, EA1, HBK1, HUK1, IA, Kca1-1, Kcna, Kcna1, Kcpvd, Kv1.1, MBK1, mceph, megencephaly, MGC126782, MGC138385, MK1, Mk-1, MKI, potassium (K+) channel protein voltage dependent, potassium channel, voltage gated shaker related subfamily A, member 1, potassium voltage gated channel shaker related subfamily member 1, potassium voltage gated channel, shaker related subfamily, member 1, potassium voltage-gated channel subfamily A member 1, potassium voltage-gated channel, shaker-related subfamily, member 1, potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia), RBK1, RBKI, RCK1, Shak, Voltage-gated K(+) channel HuKI, voltage-gated potassium channel HBK1, Voltage-gated potassium channel subunit Kv1.1
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 16485, 24520, 3736
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Lyophilized
Applications: Western Blot
Concentration: 500 μg/mL
Formulation: PBS with 5MG BSA and 0.05MG sodium azide, 0.05MG thimerosal
Gene Accession No.: P10499, P16388, Q09470
Gene Symbols: Kcna1
Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Kv1.1 potassium channel (465-481aa IAHYRQVNIRTANCTTA).
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
KV1.1 (KCNA1)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Kcna1
Gene Alias:
AEMK, AI840627, brain potassium channel protein-1, EA1, HBK1, HUK1, IA, Kca1-1, Kcna, Kcna1, Kcpvd, Kv1.1, MBK1, mceph, megencephaly, MGC126782, MGC138385, MK1, Mk-1, MKI, potassium (K+) channel protein voltage dependent, potassium channel, voltage gated shaker related subfamily A, member 1, potassium voltage gated channel shaker related subfamily member 1, potassium voltage gated channel, shaker related subfamily, member 1, potassium voltage-gated channel subfamily A member 1, potassium voltage-gated channel, shaker-related subfamily, member 1, potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia), RBK1, RBKI, RCK1, Shak, Voltage-gated K(+) channel HuKI, voltage-gated potassium channel HBK1, Voltage-gated potassium channel subunit Kv1.1
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
16485, 24520, 3736
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Lyophilized
Applications:
Western Blot
Concentration:
500 μg/mL
Formulation:
PBS with 5MG BSA and 0.05MG sodium azide, 0.05MG thimerosal
Gene Accession No.:
P10499, P16388, Q09470
Gene Symbols:
Kcna1
Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human Kv1.1 potassium channel (465-481aa IAHYRQVNIRTANCTTA).
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG