PIPA595371
TPL2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA595371-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA595371 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
TPL2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
MAP3K8
Gene Alias
augmented in rheumatoid arthritis 2, AURA2, Cancer Osaka thyroid oncogene, cancer Osaka thyroid, oncogene, CCOT, c-COT, COT, cot (cancer Osaka thyroid) oncogene, COT proto-oncogene serine/threonine-protein kinase, Cot/Tpl2, D17TPL2, EC 1.14.16.2, Est, Estf, Ewing sarcoma transformant, FLJ10486, M3K8, MAP3K 8, Map3k8, MEKK8, mitogen activated protein kinase kinase kinase 8, mitogen-activated protein kinase kinase kinase 8, Protein kinase cot, Proto-oncogene c-Cot, proto-oncogene serine/threoine protein kinase, serine/threonine kinase (Tpl-2), serine/threonine-protein kinase cot, TH isoform 3, TH isoform a, TH-4, TPL 2, Tpl2, TPL-2, Tumor progression locus 2, TY3H, TYH
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
116596, 1326
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Lyophilized
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
500 μg/mL
Formulation
PBS with 5MG BSA and 0.05MG sodium azide
Gene Accession No.
P41279, Q63562
Gene Symbols
MAP3K8
Immunogen
E.coli-derived human MAP3K8 recombinant protein (Position: D9-L193).
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Human MAP3K8 shares 89.7% and 90.3% amino acid (aa) sequence identity with mouse and rat MAP3K8, respectively
- Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL
- MAP3K8 (COT) is a serine/threonine kinase which can activate both the MAP and JNK kinase pathways and plays a role in the cell cycle
- Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase (MAPKKK or MEKK)
- MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK, which in turn activates MAPK
- The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells
- MEKK8 is able to activate NF-kappa-B 1 by stimulating proteasome-mediated proteolysis of NF-kappa-B 1/p105
- This cytoplasmic protein is expressed in several normal tissues and human tumor-derived cell lines
- The 58 kDa form is activated specifically during the S and G2/M phases of the cell cycle
- The longer form undergoes phosphorylation on Ser residues mainly, and the shorter form on both Ser and Thr residues.
Compare Similar Items
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Antigen: TPL2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MAP3K8
Gene Alias: augmented in rheumatoid arthritis 2, AURA2, Cancer Osaka thyroid oncogene, cancer Osaka thyroid, oncogene, CCOT, c-COT, COT, cot (cancer Osaka thyroid) oncogene, COT proto-oncogene serine/threonine-protein kinase, Cot/Tpl2, D17TPL2, EC 1.14.16.2, Est, Estf, Ewing sarcoma transformant, FLJ10486, M3K8, MAP3K 8, Map3k8, MEKK8, mitogen activated protein kinase kinase kinase 8, mitogen-activated protein kinase kinase kinase 8, Protein kinase cot, Proto-oncogene c-Cot, proto-oncogene serine/threoine protein kinase, serine/threonine kinase (Tpl-2), serine/threonine-protein kinase cot, TH isoform 3, TH isoform a, TH-4, TPL 2, Tpl2, TPL-2, Tumor progression locus 2, TY3H, TYH
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 116596, 1326
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Lyophilized
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 500 μg/mL
Formulation: PBS with 5MG BSA and 0.05MG sodium azide
Gene Accession No.: P41279, Q63562
Gene Symbols: MAP3K8
Immunogen: E.coli-derived human MAP3K8 recombinant protein (Position: D9-L193).
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
TPL2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MAP3K8
Gene Alias:
augmented in rheumatoid arthritis 2, AURA2, Cancer Osaka thyroid oncogene, cancer Osaka thyroid, oncogene, CCOT, c-COT, COT, cot (cancer Osaka thyroid) oncogene, COT proto-oncogene serine/threonine-protein kinase, Cot/Tpl2, D17TPL2, EC 1.14.16.2, Est, Estf, Ewing sarcoma transformant, FLJ10486, M3K8, MAP3K 8, Map3k8, MEKK8, mitogen activated protein kinase kinase kinase 8, mitogen-activated protein kinase kinase kinase 8, Protein kinase cot, Proto-oncogene c-Cot, proto-oncogene serine/threoine protein kinase, serine/threonine kinase (Tpl-2), serine/threonine-protein kinase cot, TH isoform 3, TH isoform a, TH-4, TPL 2, Tpl2, TPL-2, Tumor progression locus 2, TY3H, TYH
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
116596, 1326
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Lyophilized
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
500 μg/mL
Formulation:
PBS with 5MG BSA and 0.05MG sodium azide
Gene Accession No.:
P41279, Q63562
Gene Symbols:
MAP3K8
Immunogen:
E.coli-derived human MAP3K8 recombinant protein (Position: D9-L193).
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: CD273 (B7-DC)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PDCD1LG2
Gene Alias: B7 dendritic cell molecule, B7DC, B7-DC, bA574F11.2, Btdc, Butyrophilin B7-DC, butyrophilin-like protein, CD273, F730015O22Rik, MGC124039, MGC124040, PD1 ligand 2, PD-1 ligand 2, PD-1-ligand 2, PDCD1 ligand 2, PDCD1L2, Pdcd1lg2, Pdl2, PD-L2, Programmed cell death 1 ligand 2, programmed death ligand 2
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 80380
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Lyophilized
Applications: Western Blot
Concentration: 500 μg/mL
Formulation: PBS with 5MG BSA and 0.05MG sodium azide
Gene Accession No.: Q9BQ51
Gene Symbols: PDCD1LG2
Immunogen: E.coli-derived human B7 DC recombinant protein (Position: L20-T220).
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
CD273 (B7-DC)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PDCD1LG2
Gene Alias:
B7 dendritic cell molecule, B7DC, B7-DC, bA574F11.2, Btdc, Butyrophilin B7-DC, butyrophilin-like protein, CD273, F730015O22Rik, MGC124039, MGC124040, PD1 ligand 2, PD-1 ligand 2, PD-1-ligand 2, PDCD1 ligand 2, PDCD1L2, Pdcd1lg2, Pdl2, PD-L2, Programmed cell death 1 ligand 2, programmed death ligand 2
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
80380
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Lyophilized
Applications:
Western Blot
Concentration:
500 μg/mL
Formulation:
PBS with 5MG BSA and 0.05MG sodium azide
Gene Accession No.:
Q9BQ51
Gene Symbols:
PDCD1LG2
Immunogen:
E.coli-derived human B7 DC recombinant protein (Position: L20-T220).
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: VAMP7
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Vamp7
Gene Alias: Sybl1, synaptobrevin-like 1, synaptobrevin-like protein 1, tetanus neurotoxin-insensitive VAMP, tetanus-insensitive VAMP, TIVAMP, Ti-VAMP, vamp, Vamp7, VAMP-7, vesicle associated membrane protein 7, vesicle-associated membrane protein 7
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 6845, 85491
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Lyophilized
Applications: Western Blot
Concentration: 500 μg/mL
Formulation: PBS with 5MG BSA and 0.05MG sodium azide
Gene Accession No.: P51809, Q9JHW5
Gene Symbols: Vamp7
Immunogen: E.coli-derived human SYBL1 recombinant protein (Position: N24-T190).
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
VAMP7
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Vamp7
Gene Alias:
Sybl1, synaptobrevin-like 1, synaptobrevin-like protein 1, tetanus neurotoxin-insensitive VAMP, tetanus-insensitive VAMP, TIVAMP, Ti-VAMP, vamp, Vamp7, VAMP-7, vesicle associated membrane protein 7, vesicle-associated membrane protein 7
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
6845, 85491
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Lyophilized
Applications:
Western Blot
Concentration:
500 μg/mL
Formulation:
PBS with 5MG BSA and 0.05MG sodium azide
Gene Accession No.:
P51809, Q9JHW5
Gene Symbols:
Vamp7
Immunogen:
E.coli-derived human SYBL1 recombinant protein (Position: N24-T190).
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: ACVR2A
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ACVR2A
Gene Alias: activin A receptor type 2A, activin A receptor type IIA, activin A receptor, type IIA, activin receptor IIA, activin receptor type IIA, Activin receptor type-2A, Actrii, ActrIIa, ACTR-IIA, ACVR2, Acvr2a, rActR-II, TactrII, type II activin receptor
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 11480, 29263, 92
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Lyophilized
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 500 μg/mL
Formulation: PBS with 5MG BSA and 0.05MG sodium azide
Gene Accession No.: P27037, P27038, P38444
Gene Symbols: ACVR2A
Immunogen: E.coli-derived human ACVR2A recombinant protein (Position: Q421-L513).
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
ACVR2A
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ACVR2A
Gene Alias:
activin A receptor type 2A, activin A receptor type IIA, activin A receptor, type IIA, activin receptor IIA, activin receptor type IIA, Activin receptor type-2A, Actrii, ActrIIa, ACTR-IIA, ACVR2, Acvr2a, rActR-II, TactrII, type II activin receptor
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
11480, 29263, 92
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Lyophilized
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
500 μg/mL
Formulation:
PBS with 5MG BSA and 0.05MG sodium azide
Gene Accession No.:
P27037, P27038, P38444
Gene Symbols:
ACVR2A
Immunogen:
E.coli-derived human ACVR2A recombinant protein (Position: Q421-L513).
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG