PIPA595340

SFRP4 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA595340-Each-of-1 In Stock ₹ 44,705.10

PIPA595340 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

SFRP4

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SFRP4

Gene Alias

Ddc4, DDC-4 protein, Frizzled protein, human endometrium, frizzled related protein, frizzled-related protein, frizzled-related protein 4, FRP, FRP-4, FRPHE, MGC26498, secreted frizzled related protein 4, secreted frizzled-related protein 4, secreted frizzled-related protein 4, secreted frizzled-related protein 4, secreted frizzled-related sequence protein 4, Sfrp4, sFRP-4

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

6424

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Lyophilized

Applications

ELISA, Immunohistochemistry (Paraffin), Western Blot

Concentration

500 μg/mL

Formulation

PBS with 5MG BSA and 0.05MG sodium azide

Gene Accession No.

Q6FHJ7

Gene Symbols

SFRP4

Immunogen

E.coli-derived human SFRP4 recombinant protein (Position: A22-K303).

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Human SFRP4 shares 96.8% and 96.1% amino acid (aa) sequence identity with mouse and rat SFRP4, respectively
  • Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL
  • Secreted Frizzled-Related Proteins (sFRPs) are a family of glycosylated Wnt antagonists characterized by a conserved cysteine-rich domain that shares homology with the cysteine-rich, extracellular domain Frizzled proteins use for the binding of Wnt proteins and receptors
  • Lacking the transmembrane and intracellular domains of the Frizzled proteins, sFRPs function as soluble modulators of the Wnt signaling pathway through the direct binding of Wnt proteins to this cysteine-rich domain, and the resultant inhibition of Wnt receptor binding and signaling capabilities
  • sFRP-4 is widely distributed in a variety of embryonic and adult tissues where it can function as a circulating antiangiogenic factor, a potent proapoptotic factor, an inhibitor of insulin secretion, and a suppressor of both tumor growth and metastatic potential through disruption of the Wnt signaling pathway
  • Research has demonstrated the existence of a direct correlation between the downregulation and/or absence of circulating sFRP-4 and the progression of several cancer types, including ovarian, endometrial, prostate and lung
  • Upregulation of circulating sFRP-4 has been linked to the deterioration of glucose metabolism in the case of type 2 diabetes, as well as the suppression of the keratinocyte hyperproliferation and epidermal hyperlasia that are definitive of psoriasis.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA595340

--


Antigen:
SFRP4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SFRP4

Gene Alias:
Ddc4, DDC-4 protein, Frizzled protein, human endometrium, frizzled related protein, frizzled-related protein, frizzled-related protein 4, FRP, FRP-4, FRPHE, MGC26498, secreted frizzled related protein 4, secreted frizzled-related protein 4, secreted frizzled-related protein 4, secreted frizzled-related protein 4, secreted frizzled-related sequence protein 4, Sfrp4, sFRP-4

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
6424

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Lyophilized

Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 5MG BSA and 0.05MG sodium azide

Gene Accession No.:
Q6FHJ7

Gene Symbols:
SFRP4

Immunogen:
E.coli-derived human SFRP4 recombinant protein (Position: A22-K303).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA595344

--


Antigen:
CLN2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TPP1

Gene Alias:
cell growth-inhibiting gene 1 protein, ceroid-lipofuscinosis, neuronal 2, CLN 2, CLN2, GIG 1, GIG1, growth-inhibiting protein 1, LPIC, lysosomal pepstatin insensitive protease, lysosomal pepstatin-insensitive protease, MGC21297, SCAR7, TPP 1, TPP I, Tpp1, TPP-1, TPPI, TPP-I, Tripeptidyl aminopeptidase, tripeptidyl peptidase 1, tripeptidyl peptidase I, tripeptidyl peptidase-I, tripeptidyl-peptidase 1, Tripeptidyl-peptidase I, UNQ267/PRO304

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1200

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 5MG BSA and 0.05MG sodium azide

Gene Accession No.:
O14773

Gene Symbols:
TPP1

Immunogen:
A synthetic peptide corresponding to a sequence in the middle region of human TPP1 (227-261aa CAQFLEQYFHDSDLAQFMRLFGGNFAHQASVARVV).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA595345

--


Antigen:
TRPM4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TRPM4

Gene Alias:
1110030C19Rik, AW047689, Calcium-activated non-selective cation channel 1, H LTrpC-4, hTRPM4, Long transient receptor potential channel 4, LOW QUALITY PROTEIN: transient receptor potential cation channel subfamily M member 4, LTrpC4, LTrpC-4, melastatin like 2 protein, melastatin-4, Melastatin-like 2, MLS2s, PFHB1B, transient receptor potential cation channel subfamily M member 4, transient receptor potential cation channel, subfamily M, member 4, transient receptor potential ion channel melastatin subgroup member 4, Trpm4, TRPM4B

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
54795

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 4MG trehalose and no preservative

Gene Accession No.:
Q8TD43

Gene Symbols:
TRPM4

Immunogen:
E.coli-derived human TRPM4 recombinant protein (Position: F1079-D1214).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA595347

--


Antigen:
AFG3L2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
AFG3L2

Gene Alias:
2310036I02Rik, AFG3 ATPase family gene 3-like 2, AFG3 ATPase family member 3-like 2, AFG3 like AAA ATPase 2, AFG3 like matrix AAA peptidase subunit 2, AFG3(ATPase family gene 3)-like 2, AFG3L2, AFG3-like AAA ATPase 2, AFG3-like protein 2, AFG3-like protein 2 (Paraplegin-like protein), ATPase family gene 3, yeast, AW260507, Emv66, FLJ25993, par, paraplegin-like protein, SCA28, si:ch211-12e1.4, similar to AFG3-like protein 2 (Paraplegin-like protein), SPAX5

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10939, 307350, 69597

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Lyophilized

Applications:
Flow Cytometry, Immunocytochemistry, Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 5MG BSA and 0.05MG sodium azide

Gene Accession No.:
Q8JZQ2, Q9Y4W6

Gene Symbols:
AFG3L2

Immunogen:
E.coli-derived human AFG3L2 recombinant protein (Position: R168-D250).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG