PIPA595448

TLR2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA595448-Each-of-1 In Stock ₹ 44,705.10

PIPA595448 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

TLR2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Tlr2

Gene Alias

CD282, Ly105, TIL4, Tlr2, TLR-2, toll like receptor 2, toll/interleukin-1 receptor-like protein 4, Toll-like receptor, toll-like receptor 2, toll-like receptor 2 variant 1, toll-like receptor 2 variant 2, toll-like-receptor 2, exon 1a_, Toll-like-receptor, exon 1b, Toll-like-receptor, exon 1b_, Toll-like-receptor2, exon 1a

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

24088, 310553, 7097

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Lyophilized

Applications

Western Blot

Concentration

500 μg/mL

Formulation

PBS with 4MG trehalose and 0.05MG sodium azide

Gene Accession No.

O60603, Q9QUN7

Gene Symbols

Tlr2

Immunogen

E.coli-derived human TLR2 recombinant protein (Position: H610-S784).

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Human TLR2 shares 87.4% amino acid (aa) sequence identity with mouse TLR2
  • Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL
  • TLR2 is a member of the Toll-like receptor (TLR) family which play a fundamental role in pathogen recognition and activation of innate immunity
  • TLR proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors such as Protein Kinase C (PKC) alpha/beta and NF-kappa-B
  • TLR2 can form heterodimers with either TLR1 or TLR6, and as a heterodimer, can recognize a variety of bacterial and mycoplasma lipoproteins respectively
  • TLRs are highly conserved from Drosophila to humans and share structural and functional similarities
  • The various TLRs exhibit different patterns of expression
  • TLR2 is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB
  • TLR2 aids in the recognition of pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity
  • Ten human homologs of TLRs (TLR1-10) have been described
  • TLR2 is expressed in human cells such as tonsils, microglia, lymph nodes, and appendices, activated B-cells in germinal centers
  • CD14+ monocytes express the highest level of TLR2 followed by CD15+ granulocytes, CD19+ B-cells, and CD3+ T-cells
  • The expression of TLR2 on different cell types are regulated by different immune response modifiers
  • For example, LPS, GM-CSF, IL-1, and IL-10 up regulates TLR2 whereas IL-4, IFN-gamma, and TNF down regulate TLR2 expression in monocytes.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA595448

--


Antigen:
TLR2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Tlr2

Gene Alias:
CD282, Ly105, TIL4, Tlr2, TLR-2, toll like receptor 2, toll/interleukin-1 receptor-like protein 4, Toll-like receptor, toll-like receptor 2, toll-like receptor 2 variant 1, toll-like receptor 2 variant 2, toll-like-receptor 2, exon 1a_, Toll-like-receptor, exon 1b, Toll-like-receptor, exon 1b_, Toll-like-receptor2, exon 1a

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
24088, 310553, 7097

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Lyophilized

Applications:
Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 4MG trehalose and 0.05MG sodium azide

Gene Accession No.:
O60603, Q9QUN7

Gene Symbols:
Tlr2

Immunogen:
E.coli-derived human TLR2 recombinant protein (Position: H610-S784).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA595450

--


Antigen:
ATOH1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Atoh1

Gene Alias:
ATH1, Atoh1, atonal bHLH transcription factor 1, atonal homolog 1, atonal homolog 1 (Drosophila), atonal homolog bHLH transcription factor 1, BHLHA14, Class A basic helix-loop-helix protein 14, H MATH-1, Hath1, Helix-loop-helix protein hATH-1, helix-loop-helix protein mATH-1, Math1, MATH-1, Protein atonal homolog 1, RGD1565171

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
474, 500156

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Lyophilized

Applications:
Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 4MG trehalose and no preservative

Gene Accession No.:
Q92858

Gene Symbols:
Atoh1

Immunogen:
A synthetic peptide corresponding to a sequence at the N-terminus of human MATH1/HATH1 (1-30aa MSRLLHAEEWAEVKELGDHHRQPQPHHLPQ).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA595452

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Antigen:
DDX3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DDX3X

Gene Alias:
ATP-dependent RNA helicase DDX3X, CAP-Rf, D1Pas1-related sequence 2, D1Pas1-rs2, DBX, DDX14, DDX3, Ddx3x, D-E-A-D (aspartate-glutamate-alanine-aspartate) box polypeptide 3, DEAD (aspartate-glutamate-alanine-aspartate) box polypeptide 3, DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked, DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked, DEAD box protein 3, X-chromosomal, DEAD box RNA helicase DEAD3, DEAD box, X isoform, DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, X-linked, DEAD/H box-3, Dead3, DEAD-box helicase 3, X-linked, DEAD-box protein 3 (DEAD-box RNA helicase DEAD3) (mDEAD3) (Embryonic RNA helicase) (D1PAS1 related sequence 2), Embryonic RNA helicase, Erh, fibroblast growth factor inducible 14, Fin14, Helicase-like protein 2, HLP2, mDEAD3, MRX102

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
13205, 1654, 317335

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Lyophilized

Applications:
Flow Cytometry, Immunocytochemistry, Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 4MG trehalose and 0.05MG sodium azide

Gene Accession No.:
O00571, Q62167

Gene Symbols:
DDX3X

Immunogen:
A synthetic peptide corresponding to a sequence at the N-terminus of human DDX3 (2-28aa SHVAVENALGLDQQFAGLDLNSSDNQS).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA595453

--


Antigen:
HOXB1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Hoxb1

Gene Alias:
HCFP3, homeo box B1, homeobox B1, homeobox protein Hox-2.9, Homeobox protein Hox-2I, homeobox protein Hox-B1, HOX2, Hox-2.9, Hox-29, HOX2I, Hoxb1, Hoxb-1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
15407, 303491, 3211

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Lyophilized

Applications:
Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 4MG trehalose and 0.05MG sodium azide

Gene Accession No.:
P14653, P17919

Gene Symbols:
Hoxb1

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human HOXB1 (176-220aa TARTFDWMKVKRNPPKTAKVSEPGLGSPSGLRTNFTTRQLTELEK).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG