PIPA595455
IL-1 beta Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA595455-Each-of-1 | In Stock | ₹ 44,277.30 |
PIPA595455 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,277.30
GST (18%): ₹ 7,969.914
Total Price: ₹ 52,247.214
Antigen
IL-1 beta
Classification
Polyclonal
Conjugate
Unconjugated
Gene
IL1B
Gene Alias
catabolin, cytokine, Hematopoietin 1 (H1), IFN beta inducing factor, il 1b, IL 1β, IL-1, IL1 B, IL-1 beta, IL-1 precursor, IL1B, IL-1B, IL1B1, IL1beta, IL-1beta, IL1-BETA, IL1F2, IL1β, ILN, Interleukin, interleukin 1 beta, Interleukin 1 beta precursor, interleukin 1, beta, interleukin 1, beta 1, interleukin 1-beta, interleukin*1*beta, Interleukin1 beta, interleukin-1 beta, interleukin-1 beta precursor, interleukin-1 beta precursor (AA -113 to 153), interleukin-1 beta proprotein, interleukin-1b, interleukin-1beta, interleukin-beta, LAF, lymphocyte proliferation-potentiating factor, Osteoclast activating factor (OAF), preinterleukin 1 beta, Pro interleukin 1 beta, prointerleukin-1 beta, pro-interleukin-1-beta
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
16176, 24494, 3553
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Lyophilized
Applications
Western Blot
Concentration
500 μg/mL
Formulation
PBS with 4MG trehalose and 0.05MG sodium azide
Gene Accession No.
P01584, P10749, Q63264
Gene Symbols
IL1B
Immunogen
E.coli-derived human IL-1 beta recombinant protein (Position: A117-S269).
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Human IL-1 beta shares 78.3% and 77.6% amino acid (aa) sequence identity with mouse and rat IL-1 beta, respectively
- Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL
- Interleukin-1 beta (IL-1 beta) is a proinflammatory cytokine expressed by monocytes, macrophages, and dendritic cells
- IL-1 beta is synthesized in response to inflammatory stimuli as a 31 kDa inactive pro-form that accumulates in the cytosol
- Cleavage of pro-IL-1 beta into the active 17 kDa protein requires the activation of inflammasomes, which are multi-protein complexes that respond to pathogens, stress conditions, and other danger signals
- Inflammasome activation triggers the processing of the caspase-1 precursor into its active form, which in turn cleaves pro-IL-1 beta
- IL-1 beta lacks a signal sequence peptide for classical ER/Golgi pathway and is secreted alongside caspase-1 via an alternate and incompletely understood mechanism
- Although IL-1 beta is most often secreted in its active form, secretion of the uncleaved protein may be detectable under some biological conditions
- IL-1 beta signals through two receptors, IL-1RI and IL-1RII, both of which are shared with IL-1 alpha
- IL-1 beta activity can be moderated by IL-1 Receptor Antagonist (IL-1RA), a protein produced by many cell types that blocks receptor binding through competitive inhibition
- IL-1 beta play an important role in innate host defense by triggering the production of other proinflammatory cytokines in target cells and initiating acute-phase responses to infection and injury
- Elevated levels of IL-1 beta have been associated with many chronic inflammatory conditions IL-1 beta neutralizing antibodies potential therapeutic value.
Compare Similar Items
Show Difference
Antigen: IL-1 beta
Classification: Polyclonal
Conjugate: Unconjugated
Gene: IL1B
Gene Alias: catabolin, cytokine, Hematopoietin 1 (H1), IFN beta inducing factor, il 1b, IL 1β, IL-1, IL1 B, IL-1 beta, IL-1 precursor, IL1B, IL-1B, IL1B1, IL1beta, IL-1beta, IL1-BETA, IL1F2, IL1β, ILN, Interleukin, interleukin 1 beta, Interleukin 1 beta precursor, interleukin 1, beta, interleukin 1, beta 1, interleukin 1-beta, interleukin*1*beta, Interleukin1 beta, interleukin-1 beta, interleukin-1 beta precursor, interleukin-1 beta precursor (AA -113 to 153), interleukin-1 beta proprotein, interleukin-1b, interleukin-1beta, interleukin-beta, LAF, lymphocyte proliferation-potentiating factor, Osteoclast activating factor (OAF), preinterleukin 1 beta, Pro interleukin 1 beta, prointerleukin-1 beta, pro-interleukin-1-beta
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 16176, 24494, 3553
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Lyophilized
Applications: Western Blot
Concentration: 500 μg/mL
Formulation: PBS with 4MG trehalose and 0.05MG sodium azide
Gene Accession No.: P01584, P10749, Q63264
Gene Symbols: IL1B
Immunogen: E.coli-derived human IL-1 beta recombinant protein (Position: A117-S269).
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
IL-1 beta
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
IL1B
Gene Alias:
catabolin, cytokine, Hematopoietin 1 (H1), IFN beta inducing factor, il 1b, IL 1β, IL-1, IL1 B, IL-1 beta, IL-1 precursor, IL1B, IL-1B, IL1B1, IL1beta, IL-1beta, IL1-BETA, IL1F2, IL1β, ILN, Interleukin, interleukin 1 beta, Interleukin 1 beta precursor, interleukin 1, beta, interleukin 1, beta 1, interleukin 1-beta, interleukin*1*beta, Interleukin1 beta, interleukin-1 beta, interleukin-1 beta precursor, interleukin-1 beta precursor (AA -113 to 153), interleukin-1 beta proprotein, interleukin-1b, interleukin-1beta, interleukin-beta, LAF, lymphocyte proliferation-potentiating factor, Osteoclast activating factor (OAF), preinterleukin 1 beta, Pro interleukin 1 beta, prointerleukin-1 beta, pro-interleukin-1-beta
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
16176, 24494, 3553
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Lyophilized
Applications:
Western Blot
Concentration:
500 μg/mL
Formulation:
PBS with 4MG trehalose and 0.05MG sodium azide
Gene Accession No.:
P01584, P10749, Q63264
Gene Symbols:
IL1B
Immunogen:
E.coli-derived human IL-1 beta recombinant protein (Position: A117-S269).
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: IL1RA
Classification: Polyclonal
Conjugate: Unconjugated
Gene: IL1RN
Gene Alias: Anakinra, CD121A, cytokine, D2S1473, DIRA, F630041P17Rik, ICIL-1RA, IL 1 receptor antagonist, IL1 inhibitor, il1 receptor, il-1 receptor, IL1 receptor antagonist, IL1F3, IL1R, il-1r, IL1RA, IL-1RA, IL1-RA, IL-1ra3, IL-1R-alpha, IL1RN, IL-1RN, IL1RN (IL1F3), interleukin 1 receptor antagonist, interleukin-1 receptor, interleukin-1 receptor antagonist, interleukin-1 receptor antagonist protein, interleukin-1 receptor antagonist secretory form, intracellular IL-1 receptor antagonist type II, intracellular interleukin-1 receptor antagonist (icIL-1ra), IRAP, IRAP1, MGC10430, MVCD4, P80, type II interleukin-1 receptor antagonist
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 60582
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Lyophilized
Applications: Western Blot
Concentration: 500 μg/mL
Formulation: PBS with 4MG trehalose and 0.05MG sodium azide
Gene Accession No.: P25086
Gene Symbols: IL1RN
Immunogen: E.coli-derived rat IL1RA recombinant protein (Position: H27-Q178).
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Rat
Product Type: Antibody
Isotype: IgG
Antigen:
IL1RA
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
IL1RN
Gene Alias:
Anakinra, CD121A, cytokine, D2S1473, DIRA, F630041P17Rik, ICIL-1RA, IL 1 receptor antagonist, IL1 inhibitor, il1 receptor, il-1 receptor, IL1 receptor antagonist, IL1F3, IL1R, il-1r, IL1RA, IL-1RA, IL1-RA, IL-1ra3, IL-1R-alpha, IL1RN, IL-1RN, IL1RN (IL1F3), interleukin 1 receptor antagonist, interleukin-1 receptor, interleukin-1 receptor antagonist, interleukin-1 receptor antagonist protein, interleukin-1 receptor antagonist secretory form, intracellular IL-1 receptor antagonist type II, intracellular interleukin-1 receptor antagonist (icIL-1ra), IRAP, IRAP1, MGC10430, MVCD4, P80, type II interleukin-1 receptor antagonist
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
60582
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Lyophilized
Applications:
Western Blot
Concentration:
500 μg/mL
Formulation:
PBS with 4MG trehalose and 0.05MG sodium azide
Gene Accession No.:
P25086
Gene Symbols:
IL1RN
Immunogen:
E.coli-derived rat IL1RA recombinant protein (Position: H27-Q178).
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: IL-22
Classification: Polyclonal
Conjugate: Unconjugated
Gene: IL22
Gene Alias: Cytokine Zcyto18, EGK_03903, il 22, IL-10-related T-cell-derived inducible factor, IL-10-related T-cell-derived-inducible factor, IL-21, IL22, IL-22, Il22a, IL-22a, IL-D110, ILN, ILTIF, IL-TIF, ILTIF alpha, IL-TIF alpha, ILTIFa, Interleukin, interleukin 10-related T cell-derived inducible factor, interleukin 22, Interleukin22, interleukin-22, Interleukin-22a, RGD1561292, TIFa, TIFIL-23, UNQ3099/PRO10096, ZCYTO18
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 500836, 50616, 50929
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Lyophilized
Applications: ELISA, Western Blot
Concentration: 500 μg/mL
Formulation: PBS with 4MG trehalose and 0.05MG sodium azide
Gene Accession No.: Q9GZX6, Q9JJY9
Gene Symbols: IL22
Immunogen: E.coli-derived human IL-22 recombinant protein (Position: A34-I179).
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
IL-22
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
IL22
Gene Alias:
Cytokine Zcyto18, EGK_03903, il 22, IL-10-related T-cell-derived inducible factor, IL-10-related T-cell-derived-inducible factor, IL-21, IL22, IL-22, Il22a, IL-22a, IL-D110, ILN, ILTIF, IL-TIF, ILTIF alpha, IL-TIF alpha, ILTIFa, Interleukin, interleukin 10-related T cell-derived inducible factor, interleukin 22, Interleukin22, interleukin-22, Interleukin-22a, RGD1561292, TIFa, TIFIL-23, UNQ3099/PRO10096, ZCYTO18
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
500836, 50616, 50929
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Lyophilized
Applications:
ELISA, Western Blot
Concentration:
500 μg/mL
Formulation:
PBS with 4MG trehalose and 0.05MG sodium azide
Gene Accession No.:
Q9GZX6, Q9JJY9
Gene Symbols:
IL22
Immunogen:
E.coli-derived human IL-22 recombinant protein (Position: A34-I179).
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: NOTCH1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Notch1
Gene Alias: 9930111A19Rik, AOS5, AOVD1, Drosophila Notch homolog 1 (controlling the the ectodermal and neural cell fate in Drosophila), hN1, lin-12, major type A protein, Mis6, Motch, Motch A, mT14, N1, neurogenic locus notch homolog protein 1, NEXT, NICD, NOTCH, notch 1, Notch 1 extracellular truncation, Notch 1 intracellular domain, Notch gene homolog 1, Notch homolog 1, translocation-associated, notch receptor 1, Notch1, p300, RP23-306D20.12, RP23-306D20.12-001, Tan1, Translocation-associated notch protein TAN-1, transmembrane receptor Notch1
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 18128, 4851
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Lyophilized
Applications: Western Blot
Concentration: 500 μg/mL
Formulation: PBS with 4MG trehalose and 0.05MG sodium azide
Gene Accession No.: P46531, Q01705
Gene Symbols: Notch1
Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human Notch1 (1797-1827aa LKNASDGALMDDNQNEWGDEDLETKKFRFEE).
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
NOTCH1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Notch1
Gene Alias:
9930111A19Rik, AOS5, AOVD1, Drosophila Notch homolog 1 (controlling the the ectodermal and neural cell fate in Drosophila), hN1, lin-12, major type A protein, Mis6, Motch, Motch A, mT14, N1, neurogenic locus notch homolog protein 1, NEXT, NICD, NOTCH, notch 1, Notch 1 extracellular truncation, Notch 1 intracellular domain, Notch gene homolog 1, Notch homolog 1, translocation-associated, notch receptor 1, Notch1, p300, RP23-306D20.12, RP23-306D20.12-001, Tan1, Translocation-associated notch protein TAN-1, transmembrane receptor Notch1
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
18128, 4851
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Lyophilized
Applications:
Western Blot
Concentration:
500 μg/mL
Formulation:
PBS with 4MG trehalose and 0.05MG sodium azide
Gene Accession No.:
P46531, Q01705
Gene Symbols:
Notch1
Immunogen:
A synthetic peptide corresponding to a sequence in the middle region of human Notch1 (1797-1827aa LKNASDGALMDDNQNEWGDEDLETKKFRFEE).
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG