PIPA595666

Phospho-CtIP (Thr847) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA595666-Each-of-1 In Stock ₹ 47,528.58

PIPA595666 - Each of 1

₹ 47,528.58

In Stock

Quantity

1

Base Price: ₹ 47,528.58

GST (18%): ₹ 8,555.144

Total Price: ₹ 56,083.724

Antigen

Phospho-CtIP (Thr847)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Rbbp8

Gene Alias

9930104E21Rik, COM1, CtBP-interacting protein, CtIP, DNA endonuclease RBBP8, JWDS, RB binding protein 8, endonuclease, RBBP8, RBBP-8, retinoblastoma binding protein 8, retinoblastoma-binding protein 8, Retinoblastoma-interacting protein and myosin-like, RGD1308872, RIM, SAE2, SCKL2, Sporulation in the absence of SPO11 protein 2 homolog

Host Species

Rabbit

Purification Method

Antigen Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

5932

Content And Storage

-20°, C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

∽0.15 mg/mL

Formulation

10mM HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative, pH 7.5

Gene Accession No.

Q99708

Gene Symbols

Rbbp8

Immunogen

Synthetic phospho-peptide corresponding to amino acid residues surrounding Thr847 conjugated to KLH

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Antigen Affinity Purified from Pooled Serum CtIP, a 125 kD protein, was originally found interacting with a transcription repressor, CtBP, through the PLDLS motif (CtBP-Interacting Protein) thus suggested a role in transcription
  • Studies have shown that CtIP also interacts with BRCA1 protein through the c-terminus BRCT domains also suggested that CtIP is a potential tumor suppressor
  • This CtIP-BRCA1 interaction can be disrupted by DNA damaging agents including UV or gamma-irradiation
  • Li et al (Nature 406, 210 - 215 (2000)) have shown that ATM phosphorylates CtIP at serine residues 664 and 745, and mutation of these sites abrogates the dissociation of BRCA1 from CtIP, resulting in persistent repression of BRCA1-dependent induction of GADD45 upon ionizing radiation.

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Img

Thermo Scientific

PIPA595666

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Antigen:
Phospho-CtIP (Thr847)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Rbbp8

Gene Alias:
9930104E21Rik, COM1, CtBP-interacting protein, CtIP, DNA endonuclease RBBP8, JWDS, RB binding protein 8, endonuclease, RBBP8, RBBP-8, retinoblastoma binding protein 8, retinoblastoma-binding protein 8, Retinoblastoma-interacting protein and myosin-like, RGD1308872, RIM, SAE2, SCKL2, Sporulation in the absence of SPO11 protein 2 homolog

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5932

Content And Storage:
-20°, C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
∽0.15 mg/mL

Formulation:
10mM HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative, pH 7.5

Gene Accession No.:
Q99708

Gene Symbols:
Rbbp8

Immunogen:
Synthetic phospho-peptide corresponding to amino acid residues surrounding Thr847 conjugated to KLH

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA595667

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Antigen:
Phospho-DENND3 (Thr450)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DENND3

Gene Alias:
AI447457, DENN domain containing 3, DENN domain-containing protein 3, DENN/MADD domain containing 3, Dennd3, E030003N15Rik, KIAA0870

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
22898

Content And Storage:
-20°, C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.25 mg/mL

Formulation:
10mM HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative, pH 7.5

Gene Accession No.:
A2RUS2

Gene Symbols:
DENND3

Immunogen:
Synthetic phospho-peptide corresponding to amino acid residues surrounding Thr450 conjugated to KLH

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA595668

--


Antigen:
Phospho-DENND3 (Ser554)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DENND3

Gene Alias:
AI447457, DENN domain containing 3, DENN domain-containing protein 3, DENN/MADD domain containing 3, Dennd3, E030003N15Rik, KIAA0870

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
22898

Content And Storage:
-20°, C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.25 mg/mL

Formulation:
10mM HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative, pH 7.5

Gene Accession No.:
A2RUS2

Gene Symbols:
DENND3

Immunogen:
Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser554 conjugated to KLH

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA595669

--


Antigen:
Phospho-AKT1 (Thr342)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
AKT1

Gene Alias:
Akt, Akt kinase, AKT serine/threonine kinase 1, Akt/PKB, akt1, AKT1 kinase, AKT1m, Akt1m protein, Akt1-PA, Akt1-PB, Akt1-PC, Akt1-PD, Akt1-PE, CAKT, C-AKT, CG4006, CG4006-PA, CG4006-PB, CG4006-PC, CG4006-PD, CG4006-PE, CWS6, dAkt, D-Akt, dAkt kinase, dAKT/dPKB, dAkt/PKB, DAKT1, DAKT1/PKB, Dmel\CG4006, Dmel_CG4006, dPKB, DRAC-PK, DRAC-PK66, DRAC-PK85, l(3)04226, l(3)89Bq, murine thymoma viral (v-akt) oncogene homolog 1, pAkt, P-AKT, PKB, PKB alpha, PKB beta, PKB gamma, PKB/AKT, PKB/dAKT, PKBalpha, PKB-ALPHA, PKBG, PRKBA, protein kinase B, Protein kinase B alpha, protein kinase B-alpha, proto-oncogene c-Akt, RAC, rac protein kinase alpha, RAC protein kinase alpha RAC-PK alpha, RAC serine/threonine protein kinase, RAC serine/threonine-protein kinase, RAC-ALPHA, RAC-alpha serine/threonine-protein kinase, RacPK, RAC-PK-alpha, RAC-PK-beta, RAC-PK-gamma, related to A and C kinases, related to PKA to PKC protein kinases, related to the A and C kinases, SD10374p, serine/threonine protein kinase, serine-threonine protein kinase, Thymoma viral proto-oncogene, thymoma viral proto-oncogene 1, v-akt murine thymoma viral oncogene homolog 1, v-akt murine thymoma viral oncogene-like protein 1

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
41957

Content And Storage:
-20°, C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.25 mg/mL

Formulation:
10mM HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative, pH 7.5

Gene Accession No.:
Q8INB9

Gene Symbols:
AKT1

Immunogen:
Synthetic phospho-peptide corresponding to amino acid residues surrounding Thr342 conjugated to KLH

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Drosophila

Product Type:
Antibody

Isotype:
IgG