PIPA595818

LNX2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA595818-Each-of-1 In Stock ₹ 44,277.30

PIPA595818 - Each of 1

₹ 44,277.30

In Stock

Quantity

1

Base Price: ₹ 44,277.30

GST (18%): ₹ 7,969.914

Total Price: ₹ 52,247.214

Antigen

LNX2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

LNX2

Gene Alias

9630046H24, AW209022, ligand of Numb protein X 2, ligand of numb-protein X 2, Lnx2, Numb-binding protein 2, PDZ domain containing ring finger 1, PDZ domain-containing RING finger protein 1, PDZRN1

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

140887, 222484, 360761

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

1.72 mg/mL

Formulation

PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.

Q8N448, Q91XL2

Gene Symbols

LNX2

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human LNX2 (NP_6992021)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Description

  • Immunogen sequence: MGTTSDEMVS VEQTSSSSLN PLCFECGQQH WTRENHLYNY QNEVDDDLVC HICLQPLLQP LDTPCGHTFC YKCLRNFLQE KDFCPLDRKR LHFKLCKKSS ILVHKLLDKL LVLCPFSSVC KDVMQRCDLE AHLKNRCPGA SHRRVALERR KTSRTQAEIE NENGPTLLDP AGTLSPEADC LGTGAVPVER HLTSASLSTW SEEPGLDNPA FEESAGADTT QQPLSLPEGE ITTIEIHRSN; Positive Samples: A-375, A-549, Rat thymus LNX2 (Ligand of Numb Protein X 2) protein is encoded by the LNX2 gene located on chromosome 13 in humans and is known as PDZRN1 (PDZ domain-containing RING finger 1)
  • It is through its PDZ domains that LNX2 forms oligomers and interacts with some of its target proteins
  • LNX2 is best studied as a E3 ubiquitin ligase that also contains the NPXY motifs which allows binding to the Numb protein
  • This interaction has been shown to be responsible for ubiquitination of Numb, which prevents the proteasomal degradation of Notch intracellular domain (NICD) and thus modulates the Notch signaling pathway.

Compare Similar Items

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Img

Thermo Scientific

PIPA595818

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Antigen:
LNX2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
LNX2

Gene Alias:
9630046H24, AW209022, ligand of Numb protein X 2, ligand of numb-protein X 2, Lnx2, Numb-binding protein 2, PDZ domain containing ring finger 1, PDZ domain-containing RING finger protein 1, PDZRN1

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
140887, 222484, 360761

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1.72 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
Q8N448, Q91XL2

Gene Symbols:
LNX2

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human LNX2 (NP_6992021)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA595820

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Antigen:
GRK2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GRK2

Gene Alias:
ADRBK1, Adrbk-1, adrenergic beta receptor kinase 1, adrenergic receptor kinase, beta 1, adrenergic, beta, receptor kinase 1, BARK, BARK1, Bark-1, beta ARK, Beta-adrenergic receptor kinase 1, beta-adrenergic receptor kinase 1 beta ARK1, beta-AR kinase-1, betaARK1, BETA-ARK1, beta-ARK-1, EC 2.7.1.126, G protein-coupled receptor kinase 2, G-protein coupled receptor kinase 2, G-protein-coupled receptor kinase 2, grk 2, Grk2, GRK-2

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
110355, 156, 25238

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.12 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
P25098, P26817, Q99MK8

Gene Symbols:
GRK2

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 440-689 of human GRK2 (NP_0016102)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA595821

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Antigen:
CPSF4L

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Cpsf4l

Gene Alias:
0610010C04Rik, 1500000C01Rik, cleavage and polyadenylation specific factor 4 like, cleavage and polyadenylation specific factor 4-like, Cpsf4l, D11Ertd636e, putative cleavage and polyadenylation specificity factor subunit 4-like protein, RGD1306397

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
52670

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1.63 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
__

Gene Symbols:
Cpsf4l

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-228 of mouse Cpsf4l (NP_0809582)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA595822

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Antigen:
PCM1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PCM1

Gene Alias:
2600002H09Rik, 9430077F19Rik, C030044G17Rik, hPCM-1, mPCM-1, Pcm1, PCM-1, pericentriolar material 1, pericentriolar material 1 protein, pericentriolar material 1, PCM1, pericentriolar material gene 1, PTC4, RET/PCM-1

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5108

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
0.57 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
Q15154

Gene Symbols:
PCM1

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human PCM1 (NP_0061884)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG