PIPA595919

Vinculin Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA595919-Each-of-1 In Stock ₹ 44,705.10

PIPA595919 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

Vinculin

Classification

Polyclonal

Conjugate

Unconjugated

Gene

VCL

Gene Alias

9430097D22, AA571387, AI462105, AW545629, CMD1W, CMH15, epididymis luminal protein 114, HEL114, metavinculin, meta-vinculin, metavinculin {ECO:0000250, MV, MVCL, RP11-178G16.3, UniProtKB:P18206}, unnamed protein product, Vcl, vcl {ECO:0000250, VIN, vinc, vinc 1, VINC1, Vinculin, vinculin {ECO:0000250

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

22330, 305679, 7414

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

1.76 mg/mL

Formulation

PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3

Gene Accession No.

P18206, P85972, Q64727

Gene Symbols

VCL

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 767-1066 of human Vinculin (NP_0033641)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Positive Samples: 293T, NCI-H460, HepG2, BxPC-3, U-87MG, Mouse heart, Mouse brain; Cellular Location: Cell junction, Cell membrane, Cytoplasm, Cytoplasmic side, Peripheral membrane protein, adherens junction, cytoskeleton, focal adhesion Immunogen sequence: AKREVENSED PKFREAVKAA SDELSKTISP MVMDAKAVAG NISDPGLQKS FLDSGYRILG AVAKVREAFQ PQEPDFPPPP PDLEQLRLTD ELAPPKPPLP EGEVPPPRPP PPEEKDEEFP EQKAGEVINQ PMMMAARQLH DEARKWSSKG NDIIAAAKRM ALLMAEMSRL VRGGSGTKRA LIQCAKDIAK ASDEVTRLAK EVAKQCTDKR IRTNLLQVCE RIPTISTQLK ILSTVKATML GRTNISDEES EQATEMLVHN AQNLMQSVKE TVREAEAASI KIRTDAGFTL RWVRKTPWYQ Vinculin (VCL) is a cytoskeletal protein associated with cell-cell and cell-extracellular matrix adherens-type junctions
  • It functions as one of several interacting proteins involved in anchoring F-actin to the membrane
  • It has been shown that a sequence of molecular interactions might be involved in the transmembrane assembly of adhesion plaques
  • In the assembly of adhesion plaques, the beta subunit of integrin binds to talin
  • Talin binds to vinculin that interacts with alpha-actinin and possibly with itself
  • Since alpha-actinin binds to and cross-links actin filaments, vinculin represents a key element in the transmembrane linkage of the extracellular matrix to the cytoplasmic microfilament system
  • Mutations in the gene can result in cardiomyopathy dilated 1W or familial hypertrophic 15.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA595919

--


Antigen:
Vinculin

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
VCL

Gene Alias:
9430097D22, AA571387, AI462105, AW545629, CMD1W, CMH15, epididymis luminal protein 114, HEL114, metavinculin, meta-vinculin, metavinculin {ECO:0000250, MV, MVCL, RP11-178G16.3, UniProtKB:P18206}, unnamed protein product, Vcl, vcl {ECO:0000250, VIN, vinc, vinc 1, VINC1, Vinculin, vinculin {ECO:0000250

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
22330, 305679, 7414

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1.76 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3

Gene Accession No.:
P18206, P85972, Q64727

Gene Symbols:
VCL

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 767-1066 of human Vinculin (NP_0033641)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA595920

--


Antigen:
CD1d

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CD1D

Gene Alias:
AI747460, Antigen-presenting glycoprotein CD1d, antigen-presenting glycoprotein CD1d1, Cd1, CD1.1, CD1A, Cd1d, CD1D antigen, CD1D antigen, d polypeptide, CD1d molecule, CD1d.1, Cd1d1, CD1d1 antigen, CD1d1 molecule, differentiation antigen CD1-alpha-3, HMC class I antigen-like glycoprotein CD1D, Ly-38, R3, R3G1, T-cell surface glycoprotein CD1d, T-cell surface glycoprotein CD1d1, thymocyte antigen CD1D

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12479, 912

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1.16 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
P11609, P15813

Gene Symbols:
CD1D, Cd1d1

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 20-190 of human CD1D (NP_0017571)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA595921

--


Antigen:
AIRE

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Aire

Gene Alias:
Aire, AIRE protein, AIRE1, APECED, APECED protein, APECED protein homolog, APS1, APSI, Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein, autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog, Autoimmune regulator, autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy), autoimmune regulator AIRE1a, LOW QUALITY PROTEIN: autoimmune regulator, OTTHUMP00000109529, PGA1

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11634, 294328, 326

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1.57 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
O43918, Q9Z0E3

Gene Symbols:
Aire

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 30-130 of human AIRE (NP_0003741)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA595922

--


Antigen:
Cyclin D2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CCND2

Gene Alias:
2600016F06Rik, AI256817, BF642806, C86853, CCND2, cD2, cyclin D2, Cyl-2, G1/S-specific cyclin-D2, KIAK0002, MGC102758, MPPH3, Vin1, Vin-1, Vin-1 proto-oncogene

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12444, 64033, 894

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
3.11 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
P30279, P30280, Q04827

Gene Symbols:
CCND2

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-289 of human Cyclin D2 (NP_0017501)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG