PIPA596166
AIF Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA596166-Each-of-1 | In Stock | ₹ 47,614.14 |
PIPA596166 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,614.14
GST (18%): ₹ 8,570.545
Total Price: ₹ 56,184.685
Antigen
AIF
Classification
Polyclonal
Conjugate
Unconjugated
Gene
AIFM1
Gene Alias
AG1, AGR1, Aif, AIFM1, AIFsh2, apoptosis inducing factor mitochondria associated 1, apoptosis inducing factor, mitochondria associated 1, apoptosis-inducing factor 1, mitochondrial, apoptosis-inducing factor, mitochondrion-associated 1, apoptosis-inducing factor, mitochondrion-associated, 1, CMT2D, CMTX4, COWCK, COXPD6, DFNX5, ER protein 18, ER protein 19, ERP18, ERP19, hAG-1, harlequin, Hq, hTLP19, MGC111425, mitochondrial apoptosis-inducing factor 1, NADMR, NAMSD, pcd8, PDCD8, PDIA16, programmed cell death 8 (apoptosis-inducing factor), programmed cell death protein 8, RP3-438D16.2, striatal apoptosis-inducing factor, testicular secretory protein Li 4, TLP19, UNQ713/PRO1376
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
26926, 83533, 9131
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunohistochemistry (Paraffin)
Concentration
0.58 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.
O95831, Q9JM53, Q9Z0X1
Gene Symbols
AIFM1
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 334-613 of human AIF (NP_0041991)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: FPEKGNMGKI LPEYLSNWTM EKVRREGVKV MPNAIVQSVG VSSGKLLIKL KDGRKVETDH IVAAVGLEPN VELAKTGGLE IDSDFGGFRV NAELQARSNI WVAGDAACFY DIKLGRRRVE HHDHAVVSGR LAGENMTGAA KPYWHQSMFW SDLGPDVGYE AIGLVDSSLP TVGVFAKATA QDNPKSATEQ SGTGIRSESE TESEASEITI PPSTPAVPQA PVQGEDYGKG VIFYLRDKVV VGIVLWNIFN RMPIARKIIK DGEQHEDLNE VAKLFNIHED; Positive Samples: SW620, 22Rv1, H460, PC-3, U-937, Mouse liver, Mouse kidney, Mouse heart; Cellular Location: Cytoplasm, Mitochondrion inner membrane, Mitochondrion intermembrane space, Nucleus, perinuclear region Apoptosis Inducing Factor (AIF) causes chromatin condensation and DNA fragmentation
- AIF was recently identified, and cloned
- Apoptosis is characterized by several morphological nuclear changes including chromatin condensation and nuclear fragmentation
- These changes are triggered by the activation of members of caspase family, caspase activated DNase, and several novel proteins
- Like the critical molecules, cytochrome c and caspase-9, in apoptosis, AIF localizes in mitochondria
- AIF translocates to the nucleus when apoptosis is induced and induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9
- AIF induces chromatin condensation and large scale DNA fragmentation, which are the hallmarks of apoptosis, of the isolated nucleus and the nucleus in live cells by microinjection and apoptosis stimuli
- AIF is highly conserved between human and mouse and widely expressed
- Mutations in the AIF gene cause combined oxidative phosphorylation deficiency 6, which results in a severe mitochondrial encephalomyopathy
- Alternative splicing results in multiple transcript variants of AIF and a related pseudogene has been identified on chromosome 10.
Compare Similar Items
Show Difference
Antigen: AIF
Classification: Polyclonal
Conjugate: Unconjugated
Gene: AIFM1
Gene Alias: AG1, AGR1, Aif, AIFM1, AIFsh2, apoptosis inducing factor mitochondria associated 1, apoptosis inducing factor, mitochondria associated 1, apoptosis-inducing factor 1, mitochondrial, apoptosis-inducing factor, mitochondrion-associated 1, apoptosis-inducing factor, mitochondrion-associated, 1, CMT2D, CMTX4, COWCK, COXPD6, DFNX5, ER protein 18, ER protein 19, ERP18, ERP19, hAG-1, harlequin, Hq, hTLP19, MGC111425, mitochondrial apoptosis-inducing factor 1, NADMR, NAMSD, pcd8, PDCD8, PDIA16, programmed cell death 8 (apoptosis-inducing factor), programmed cell death protein 8, RP3-438D16.2, striatal apoptosis-inducing factor, testicular secretory protein Li 4, TLP19, UNQ713/PRO1376
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 26926, 83533, 9131
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunohistochemistry (Paraffin)
Concentration: 0.58 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: O95831, Q9JM53, Q9Z0X1
Gene Symbols: AIFM1
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 334-613 of human AIF (NP_0041991)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
AIF
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
AIFM1
Gene Alias:
AG1, AGR1, Aif, AIFM1, AIFsh2, apoptosis inducing factor mitochondria associated 1, apoptosis inducing factor, mitochondria associated 1, apoptosis-inducing factor 1, mitochondrial, apoptosis-inducing factor, mitochondrion-associated 1, apoptosis-inducing factor, mitochondrion-associated, 1, CMT2D, CMTX4, COWCK, COXPD6, DFNX5, ER protein 18, ER protein 19, ERP18, ERP19, hAG-1, harlequin, Hq, hTLP19, MGC111425, mitochondrial apoptosis-inducing factor 1, NADMR, NAMSD, pcd8, PDCD8, PDIA16, programmed cell death 8 (apoptosis-inducing factor), programmed cell death protein 8, RP3-438D16.2, striatal apoptosis-inducing factor, testicular secretory protein Li 4, TLP19, UNQ713/PRO1376
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
26926, 83533, 9131
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunohistochemistry (Paraffin)
Concentration:
0.58 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
O95831, Q9JM53, Q9Z0X1
Gene Symbols:
AIFM1
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 334-613 of human AIF (NP_0041991)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: PDCD4
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PDCD4
Gene Alias: D19Ucla1, death up-regulated gene protein, death-upregulated, Dug, H731, Ma3, MGC33046, MGC33047, Neoplastic transformation inhibitor protein, nuclear antigen H731, Nuclear antigen H731-like, Pdcd4, programmed cell death 4, programmed cell death 4 (neoplastic transformation inhibitor), programmed cell death protein 4, Protein 197/15a, protein MA-3, RP11-348N5.4, Tis, topoisomerase-inhibitor suppressed protein
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 18569, 27250
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.3 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: Q53EL6, Q61823
Gene Symbols: PDCD4
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human PDCD4 (NP_0552712)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
PDCD4
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PDCD4
Gene Alias:
D19Ucla1, death up-regulated gene protein, death-upregulated, Dug, H731, Ma3, MGC33046, MGC33047, Neoplastic transformation inhibitor protein, nuclear antigen H731, Nuclear antigen H731-like, Pdcd4, programmed cell death 4, programmed cell death 4 (neoplastic transformation inhibitor), programmed cell death protein 4, Protein 197/15a, protein MA-3, RP11-348N5.4, Tis, topoisomerase-inhibitor suppressed protein
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
18569, 27250
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.3 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
Q53EL6, Q61823
Gene Symbols:
PDCD4
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human PDCD4 (NP_0552712)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: TBK1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TBK1
Gene Alias: 1200008B05Rik, AI462036, AW048562, FLJ11330, FTDALS4, NAK, NF-kappa-B-activating kinase, NF-kB-activating kinase, serine/threonine protein kinase TBK1, serine/threonine-protein kinase TBK1, T2K, TANK binding kinase 1, TANK-binding kinase 1, tbk, TBK1
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 29110, 299827, 56480
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 2.98 mg/mL
Formulation: PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.: Q9UHD2, Q9WUN2
Gene Symbols: TBK1
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 500-600 of human TBK1/NAK (NP_0373861)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
TBK1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TBK1
Gene Alias:
1200008B05Rik, AI462036, AW048562, FLJ11330, FTDALS4, NAK, NF-kappa-B-activating kinase, NF-kB-activating kinase, serine/threonine protein kinase TBK1, serine/threonine-protein kinase TBK1, T2K, TANK binding kinase 1, TANK-binding kinase 1, tbk, TBK1
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
29110, 299827, 56480
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
2.98 mg/mL
Formulation:
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.:
Q9UHD2, Q9WUN2
Gene Symbols:
TBK1
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 500-600 of human TBK1/NAK (NP_0373861)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: TPI1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Tpi1
Gene Alias: AI255506, epididymis secretory protein Li 49, HEL-S-49, Methylglyoxal synthase, MGC88108, TIM, Tpi, TPI1, Tpi-1, TPID, triosephosphate isomerase, triose-phosphate isomerase, triosephosphate isomerase 1, triose-phosphate isomerase TPI1, unnamed protein product, YD9609.05C, YDR050C
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 21991, 24849, 7167
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 1.39 mg/mL
Formulation: PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.: P17751, P48500, P60174
Gene Symbols: Tpi1
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-249 of human TPI1 (NP_0003561)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
TPI1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Tpi1
Gene Alias:
AI255506, epididymis secretory protein Li 49, HEL-S-49, Methylglyoxal synthase, MGC88108, TIM, Tpi, TPI1, Tpi-1, TPID, triosephosphate isomerase, triose-phosphate isomerase, triosephosphate isomerase 1, triose-phosphate isomerase TPI1, unnamed protein product, YD9609.05C, YDR050C
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
21991, 24849, 7167
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
1.39 mg/mL
Formulation:
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.:
P17751, P48500, P60174
Gene Symbols:
Tpi1
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-249 of human TPI1 (NP_0003561)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG