PIPA596353

alpha-ENaC Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA596353-Each-of-1 In Stock ₹ 44,191.74

PIPA596353 - Each of 1

₹ 44,191.74

In Stock

Quantity

1

Base Price: ₹ 44,191.74

GST (18%): ₹ 7,954.513

Total Price: ₹ 52,146.253

Antigen

alpha-ENaC

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SCNN1A

Gene Alias

alpha ENaC-2, alpha-ENaC, Alpha-NaCH, amiloride-sensitive epithelial sodium channel, amiloride-sensitive epithelial sodium channel alpha subunit, amiloride-sensitive sodium channel subunit alpha, amiloride-sensitive sodium channel subunit alpha 2, BESC2, ENaC, ENaC alpha, ENaCa, ENaCalpha, Epithelial Na(+) channel subunit alpha, epithelial sodium channel alpha subunit, FLJ21883, mENaC, nasal epithelial sodium channel alpha subunit, nonvoltage-gated sodium channel 1 subunit alpha, Renac, SCNEA, SCNN1, Scnn1a, sodium channel epithelial 1 alpha subunit, sodium channel, non voltage gated 1 alpha subunit, sodium channel, nonvoltage-gated 1 alpha, sodium channel, non-voltage-gated 1 alpha subunit, sodium channel, nonvoltage-gated, type I, alpha, sodium channel, nonvoltage-gated, type I, alpha polypeptide

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

20276, 25122, 6337

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

3.12 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.

P37088, P37089, Q61180

Gene Symbols

SCNN1A

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 105-225 of human SCNN1A (NP_0010291)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Description

  • Immunogen sequence: LFGEYFSYPV SLNINLNSDK LVFPAVTICT LNPYRYPEIK EELEELDRIT EQTLFDLYKY SSFTTLVAGS RSRRDLRGTL PHPLQRLRVP PPPHGARRAR SVASSLRDNN PQVDWKDWKI G; Positive Samples: Mouse lung, Mouse intestine; Cellular Location: Apical cell membrane, Cell projection, Multi-pass membrane protein, cilium Epithelial sodium channels are amiloride-sensitive members of the degenerin/epithelial sodium channel (Deg/ENaC) superfamily of ion channels
  • Members of this superfamily of ion channels share organizational similarity in that they all possess two short intracellular amino and carboxyl termini, two short membrane spanning segments, and a large extracellular loop with a conserved cysteine-rich region
  • There are three homologous isoforms of the ENaC (alpha, beta, and gamma) protein
  • ENaC in the kidney, lung, and colon plays an essential role in trans-epithelial sodium and fluid balance
  • ENaC also mediates aldosterone-dependent sodium reabsorption in the distal nephron of the kidney, thus regulating blood pressure
  • ENaC is thought to be regulated, in part, through association with the cystic fibrosis transmembrane conductance regulator (CFTR) chloride ion channel
  • Gain-of-function mutations in beta- or gamma-ENaC can cause severe arterial hypertension (Liddel’s syndrome) and loss-of-function mutations in alpha- or beta-ENaC causes pseudohypoaldosteronism (PHA-1).

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Img

Thermo Scientific

PIPA596353

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Antigen:
alpha-ENaC

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SCNN1A

Gene Alias:
alpha ENaC-2, alpha-ENaC, Alpha-NaCH, amiloride-sensitive epithelial sodium channel, amiloride-sensitive epithelial sodium channel alpha subunit, amiloride-sensitive sodium channel subunit alpha, amiloride-sensitive sodium channel subunit alpha 2, BESC2, ENaC, ENaC alpha, ENaCa, ENaCalpha, Epithelial Na(+) channel subunit alpha, epithelial sodium channel alpha subunit, FLJ21883, mENaC, nasal epithelial sodium channel alpha subunit, nonvoltage-gated sodium channel 1 subunit alpha, Renac, SCNEA, SCNN1, Scnn1a, sodium channel epithelial 1 alpha subunit, sodium channel, non voltage gated 1 alpha subunit, sodium channel, nonvoltage-gated 1 alpha, sodium channel, non-voltage-gated 1 alpha subunit, sodium channel, nonvoltage-gated, type I, alpha, sodium channel, nonvoltage-gated, type I, alpha polypeptide

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20276, 25122, 6337

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
3.12 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
P37088, P37089, Q61180

Gene Symbols:
SCNN1A

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 105-225 of human SCNN1A (NP_0010291)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA596354

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Antigen:
GNAS

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GNAS

Gene Alias:
5530400H20Rik, A930027G11Rik, Adenylate cyclase-stimulating G alpha protein, AHO, ALEX, GNAS, NESP55, alpha-stimulatory subunit of GTP-binding protein, alternative gene product encoded by XL-exon, C130027O20Rik, C20orf45, dJ309F20.1.1, dJ806M20.3.3, Extra large alphas protein, G protein alpha subunit, G protein subunit alpha S, GAIPIRRH peptide, G-alpha-8, Galphas, Gnas, GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus, gnas {ECO:0000312, GNAS complex locus, GNAS complex locus, SCG6 (secretogranin VI), GNAS1, Gnasxl, Gnpas, GPIPIRRH peptide, GPSA, Gs alpha subunit, GSA, G-SALPHA60A, GSP, GTP-binding regulatory protein (G-s-alpha)., GTP-binding regulatory protein alpha subunit exon 1, guanine nucleotide binding protein (G protein), alpha stimulating activity polypeptide 1, guanine nucleotide binding protein alpha s, guanine nucleotide binding protein alpha subunit, guanine nucleotide binding protein, alpha stimulating activity polypeptide 1, guanine nucleotide

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14683, 24896, 2778

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot

Concentration:
2.14 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
O95467, P63092, P63094, P84996, Q5JWF2, Q63803, Q6R0H6, Q6R0H7, Q9Z0F1

Gene Symbols:
GNAS

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human GNAS (NP_0005071)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA596355

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Antigen:
HAX1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Hax1

Gene Alias:
FLJ17042, FLJ18492, FLJ93803, Hax1, HAX-1, HCLS1 (and PKD2) associated protein, HCLS1 associated protein X-1, HCLS1 associated X-1, HCLS1-associated protein X-1, HCLSBP1, HS1 binding protein, HS1-associated protein X-1, HS1-associating protein X-1, HS1-binding protein 1, HS1BP1, HSP1BP-1, mHAX-1s, OTTHUMP00000034190, RP11-137P24.1, SCN3, SIG-111, Silg111

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10456, 23897, 291202

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1.34 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
O00165, O35387, Q7TSE9

Gene Symbols:
Hax1

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-279 of human HAX1 (NP_0061092)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA596357

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Antigen:
PNMT

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Pnmt

Gene Alias:
Noradrenaline N-methyltransferase, PENT, phenylethanolamine N-methylase, phenylethanolamine N-methyltransferase, phenylethanolamine-N-methyltransferase, PNMT, PNMTase

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18948, 5409

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.77 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
P11086, P40935

Gene Symbols:
Pnmt

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-282 of human PNMT (NP_0026771)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG