PIPA596921
SERPINA12 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA596921-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA596921 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
SERPINA12
Classification
Polyclonal
Conjugate
Unconjugated
Gene
SERPINA12
Gene Alias
4632419J12Rik, a12, Ol64, Ol-64, serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12, serine (or cysteine) peptidase inhibitor, clade A, member 12, serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12, serpin A12, serpin family A member 12, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12, serpin peptidase inhibitor, clade A, member 12, Serpina12, Vaspin, visceral adipose tissue-derived serine protease inhibitor, visceral adipose tissue-derived serpin, visceral adipose-specific serpin
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
145264, 68054
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
1.78 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.
Q7TMF5, Q8IW75
Gene Symbols
SERPINA12
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 20-320 of human SERPINA12 (NP_7762491)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: LLKPSFSPRN YKALSEVQGW KQRMAAKELA RQNMDLGFKL LKKLAFYNPG RNIFLSPLSI STAFSMLCLG AQDSTLDEIK QGFNFRKMPE KDLHEGFHYI IHELTQKTQD LKLSIGNTLF IDQRLQPQRK FLEDAKNFYS AETILTNFQN LEMAQKQIND FISQKTHGKI NNLIENIDPG TVMLLANYIF FRARWKHEFD PNVTKEEDFF LEKNSSVKVP MMFRSGIYQV GYDDKLSCTI LEIPYQKNIT AIFILPDEGK LKHLEKGLQV DTFSRWKTLL SRRVVDVSVP RLHMTGTFDL K; Positive Samples: Mouse brain Vaspin is a newly described adipocytokine expressed predominantly in visceral white adipose tissues
- Structure analysis of vaspin predicts the presence of three beta-sheets, nine alpha-helices, and one central loop, which are distinctive structural features of Serpin family members
- The serpins are irreversible ("esuicidal"e) serine-protease inhibitors, characterized by having more than 30% sequence homology with alpha1-antitrypsin and a conserved tertiary structure, which contains an exposed reactive center loop that acts as a pseudo-substrate for the target proteinase
- Members of this family play an important role in a number of fundamental biological processes, including blood coagulation, fibrinolysis, complement activation, angiogenesis, inflammation, and tumor suppression
- In humans, the serpins represent approximately 2% of total serum proteins, of which 70% is alpha1-antitrypsin
- Vaspin exhibits 40.2% sequence identity with alpha1-antitrypsin
- Yet, its protease inhibitory activity is still unknown
- Vaspin mRNA expression in visceral fat is positively correlated with BMI and percent of body fat
- Administration of vaspin to obese mice improved glucose tolerance and insulin sensitivity, reflected by normalized blood glucose levels
- It also led to the reversal of altered expression of diabetes-relevant adipocytokines, including leptin, adiponectin, resistin, and TNF-alpha
- These findings suggest a potential clinical use for Vaspin in ameliorating certain aberrations seen in the diabetic/obesity metabolic syndrome.
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Antigen: SERPINA12
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SERPINA12
Gene Alias: 4632419J12Rik, a12, Ol64, Ol-64, serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12, serine (or cysteine) peptidase inhibitor, clade A, member 12, serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12, serpin A12, serpin family A member 12, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12, serpin peptidase inhibitor, clade A, member 12, Serpina12, Vaspin, visceral adipose tissue-derived serine protease inhibitor, visceral adipose tissue-derived serpin, visceral adipose-specific serpin
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 145264, 68054
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 1.78 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: Q7TMF5, Q8IW75
Gene Symbols: SERPINA12
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 20-320 of human SERPINA12 (NP_7762491)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
SERPINA12
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SERPINA12
Gene Alias:
4632419J12Rik, a12, Ol64, Ol-64, serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12, serine (or cysteine) peptidase inhibitor, clade A, member 12, serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12, serpin A12, serpin family A member 12, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12, serpin peptidase inhibitor, clade A, member 12, Serpina12, Vaspin, visceral adipose tissue-derived serine protease inhibitor, visceral adipose tissue-derived serpin, visceral adipose-specific serpin
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
145264, 68054
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
1.78 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
Q7TMF5, Q8IW75
Gene Symbols:
SERPINA12
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 20-320 of human SERPINA12 (NP_7762491)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: AMOT
Classification: Polyclonal
Conjugate: Unconjugated
Gene: AMOT
Gene Alias: AMOT, Angiomotin, angiomotin p130 isoform, angiomotin p80 isoform, CAG-2, D0Kist1, KIAA1071, RGD1564027, si:dkey-13f9.6, Sii6, wu:fj21a07
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 300289
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.67 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: Q4VCS5
Gene Symbols: AMOT
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human AMOT (NP_5735721)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Rat
Product Type: Antibody
Isotype: IgG
Antigen:
AMOT
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
AMOT
Gene Alias:
AMOT, Angiomotin, angiomotin p130 isoform, angiomotin p80 isoform, CAG-2, D0Kist1, KIAA1071, RGD1564027, si:dkey-13f9.6, Sii6, wu:fj21a07
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
300289
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.67 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
Q4VCS5
Gene Symbols:
AMOT
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human AMOT (NP_5735721)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: HSD11B2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: HSD11B2
Gene Alias: 11(beta)-HSD2, 11-beta-HSD, 11-beta-HSD type II, 11-beta-HSD2, 11-beta-hydroxysteroid dehydrogenase type 2, 11-beta-hydroxysteroid dehydrogenase type II, 11-DH2, 11-HSD type II, 11HSD2, AME, AME1, corticosteroid 11-beta-dehydrogenase isozyme 2, -HSD11 type II, HSD11B2, HSD11K, HSD2, hydroxysteroid (11-beta) dehydrogenase 2, hydroxysteroid 11-beta dehydrogenase 2, Hydroxysteroid dehydrogenase, 11 beta type 2, NAD-dependent 11-beta-hydroxysteroid dehydrogenase, SDR9C3, Short chain dehydrogenase/reductase family 9C member 3
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 25117, 3291
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.48 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: P50233, P80365
Gene Symbols: HSD11B2
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 266-405 of human HSD11B2 (NP_0001873)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
HSD11B2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
HSD11B2
Gene Alias:
11(beta)-HSD2, 11-beta-HSD, 11-beta-HSD type II, 11-beta-HSD2, 11-beta-hydroxysteroid dehydrogenase type 2, 11-beta-hydroxysteroid dehydrogenase type II, 11-DH2, 11-HSD type II, 11HSD2, AME, AME1, corticosteroid 11-beta-dehydrogenase isozyme 2, -HSD11 type II, HSD11B2, HSD11K, HSD2, hydroxysteroid (11-beta) dehydrogenase 2, hydroxysteroid 11-beta dehydrogenase 2, Hydroxysteroid dehydrogenase, 11 beta type 2, NAD-dependent 11-beta-hydroxysteroid dehydrogenase, SDR9C3, Short chain dehydrogenase/reductase family 9C member 3
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
25117, 3291
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.48 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
P50233, P80365
Gene Symbols:
HSD11B2
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 266-405 of human HSD11B2 (NP_0001873)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: DDIT4
Classification: Polyclonal
Conjugate: Unconjugated
Gene: DDIT4
Gene Alias: 5830413E08Rik, AA415483, DDIT4, Dexamethasone-induced gene 2 protein, dig2, DNA damage inducible transcript 4, DNA damage-inducible transcript 4 protein, DNA-damage-inducible transcript 4, DNA-damage-inducible transcript 4 protein, HIF-1 responsive protein RTP801, HIF-1 responsive RTP801, protein regulated in development and DNA damage response 1, REDD1, REDD-1, RP11-442H21.1, RTP801
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 54541
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.72 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: Q9NX09
Gene Symbols: DDIT4
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-232 of human DDIT4 (NP_0619311)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
DDIT4
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
DDIT4
Gene Alias:
5830413E08Rik, AA415483, DDIT4, Dexamethasone-induced gene 2 protein, dig2, DNA damage inducible transcript 4, DNA damage-inducible transcript 4 protein, DNA-damage-inducible transcript 4, DNA-damage-inducible transcript 4 protein, HIF-1 responsive protein RTP801, HIF-1 responsive RTP801, protein regulated in development and DNA damage response 1, REDD1, REDD-1, RP11-442H21.1, RTP801
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
54541
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.72 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
Q9NX09
Gene Symbols:
DDIT4
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-232 of human DDIT4 (NP_0619311)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG