PIPA596923

HSD11B2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA596923-Each-of-1 In Stock ₹ 44,705.10

PIPA596923 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

HSD11B2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

HSD11B2

Gene Alias

11(beta)-HSD2, 11-beta-HSD, 11-beta-HSD type II, 11-beta-HSD2, 11-beta-hydroxysteroid dehydrogenase type 2, 11-beta-hydroxysteroid dehydrogenase type II, 11-DH2, 11-HSD type II, 11HSD2, AME, AME1, corticosteroid 11-beta-dehydrogenase isozyme 2, -HSD11 type II, HSD11B2, HSD11K, HSD2, hydroxysteroid (11-beta) dehydrogenase 2, hydroxysteroid 11-beta dehydrogenase 2, Hydroxysteroid dehydrogenase, 11 beta type 2, NAD-dependent 11-beta-hydroxysteroid dehydrogenase, SDR9C3, Short chain dehydrogenase/reductase family 9C member 3

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

25117, 3291

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

0.48 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.

P50233, P80365

Gene Symbols

HSD11B2

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 266-405 of human HSD11B2 (NP_0001873)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: KTESVRNVGQ WEKRKQLLLA NLPQELLQAY GKDYIEHLHG QFLHSLRLAM SDLTPVVDAI TDALLAARPR RRYYPGQGLG LMYFIHYYLP EGLRRRFLQA FFISHCLPRA LQPGQPGTTP PQDAAQDPNL SPGPSPAVAR; Positive Samples: HepG2; Cellular Location: Endoplasmic reticulum, Microsome There are at least two isozymes of the corticosteroid 11-beta-dehydrogenase, a microsomal enzyme complex responsible for the interconversion of cortisol and cortisone
  • The type I isozyme has both 11-beta-dehydrogenase (cortisol to cortisone) and 11-oxoreductase (cortisone to cortisol) activities
  • The type II isozyme, encoded by this gene, has only 11-beta-dehydrogenase activity
  • In aldosterone-selective epithelial tissues such as the kidney, the type II isozyme catalyzes the glucocorticoid cortisol to the inactive metabolite cortisone, thus preventing illicit activation of the mineralocorticoid receptor
  • In tissues that do not express the mineralocorticoid receptor, such as the placenta and testis, it protects cells from the growth-inhibiting and/or pro-apoptotic effects of cortisol, particularly during embryonic development
  • Mutations in this gene cause the syndrome of apparent mineralocorticoid excess and hypertension.

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Show Difference

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PIPA596923

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Antigen:
HSD11B2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
HSD11B2

Gene Alias:
11(beta)-HSD2, 11-beta-HSD, 11-beta-HSD type II, 11-beta-HSD2, 11-beta-hydroxysteroid dehydrogenase type 2, 11-beta-hydroxysteroid dehydrogenase type II, 11-DH2, 11-HSD type II, 11HSD2, AME, AME1, corticosteroid 11-beta-dehydrogenase isozyme 2, -HSD11 type II, HSD11B2, HSD11K, HSD2, hydroxysteroid (11-beta) dehydrogenase 2, hydroxysteroid 11-beta dehydrogenase 2, Hydroxysteroid dehydrogenase, 11 beta type 2, NAD-dependent 11-beta-hydroxysteroid dehydrogenase, SDR9C3, Short chain dehydrogenase/reductase family 9C member 3

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
25117, 3291

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.48 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
P50233, P80365

Gene Symbols:
HSD11B2

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 266-405 of human HSD11B2 (NP_0001873)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA596924

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Antigen:
DDIT4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DDIT4

Gene Alias:
5830413E08Rik, AA415483, DDIT4, Dexamethasone-induced gene 2 protein, dig2, DNA damage inducible transcript 4, DNA damage-inducible transcript 4 protein, DNA-damage-inducible transcript 4, DNA-damage-inducible transcript 4 protein, HIF-1 responsive protein RTP801, HIF-1 responsive RTP801, protein regulated in development and DNA damage response 1, REDD1, REDD-1, RP11-442H21.1, RTP801

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
54541

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.72 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
Q9NX09

Gene Symbols:
DDIT4

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-232 of human DDIT4 (NP_0619311)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA596925

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Antigen:
CKMT2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Ckmt2

Gene Alias:
2300008A19Rik, basic-type mitochondrial creatine kinase, CKMT2, Creatine kinase S-type, mitochondrial, creatine kinase, mitochondrial 2, creatine kinase, mitochondrial 2 (sarcomeric), creatine kinase, mitochondrial 2, sarcomeric, EC 2.7.3.2, mib-CK, sarcomeric mitochondrial creatine kinase, ScCKmit, SMTCK, S-MtCK

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1160, 688698, 76722

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1.8 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
P09605, P17540, Q6P8J7

Gene Symbols:
Ckmt2

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 40-230 of human CKMT2 (NP_0018162)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA596926

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Antigen:
Nkx3.2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NKX3-2

Gene Alias:
bagpipe homeobox gene 1 homolog, bagpipe homeobox protein homolog 1, BAPX1, homeobox protein NK-3 homolog B, Homeobox protein Nkx-3.2, homeodomain protein Nkx-3.2, NK3 homeobox 2, NKX3.2, Nkx-3.2, NKX3-2, NKX3B, SMMD

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12020, 579, 682329

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.79 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
P78367, P97503

Gene Symbols:
NKX3-2

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human NKX3-2 (NP_0011801)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG