PIPA596905

HSD3B1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA596905-Each-of-1 In Stock ₹ 44,705.10

PIPA596905 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

HSD3B1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

HSD3B1

Gene Alias

3 beta-hydroxysteroid dehydrogenase 1, 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase, 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1, 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type I, 3BETAHSD, 3-beta-HSD, 3-beta-HSD I, 3-beta-hydroxy-5-ene steroid dehydrogenase, 3-beta-hydroxy-Delta(5)-steroid dehydrogenase, 3-beta-hydroxysteroid 3-dehydrogenase, 3BH, Delta-5-3-ketosteroid isomerase, Dihydrotestosterone oxidoreductase, HGNC:5217, HSD3B, Hsd3b1, HSDB3, HSDB3A, hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1, hydroxy-delta-MAY-steroid dehydrogenase, 3 beta- and steroid delta-isomerase, hydroxysteroid dehydrogenase-1, delta<5>-3-beta, I, Progesterone reductase, SDR11E1, short chain dehydrogenase/reductase family 11E, member 1, steroid Delta-isomerase, Trophoblast antigen FDO161G, unnamed protein product

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

15492, 3283, 360348

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

0.85 mg/mL

Formulation

PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.

P14060, P22071, P24815

Gene Symbols

HSD3B1

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-290 of human HSD3B1 (NP_0008531)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: MTGWSCLVTG AGGFLGQRII RLLVKEKELK EIRVLDKAFG PELREEFSKL QNKTKLTVLE GDILDEPFLK RACQDVSVII HTACIIDVFG VTHRESIMNV NVKGTQLLLE ACVQASVPVF IYTSSIEVAG PNSYKEIIQN GHEEEPLENT WPAPYPHSKK LAEKAVLAAN GWNLKNGGTL YTCALRPMYI YGEGSRFLSA SINEALNNNG ILSSVGKFST VNPVYVGNVA WAHILALRAL QDPKKAPSIR GQFYYISDDT PHQSYDNLNY TLSKEFGLRL DSRWSFPLSL; Positive Samples: A375; Cellular Location: Endoplasmic reticulum membrane, Mitochondrion membrane, Single-pass membrane protein Amyloid beta peptide (Abeta/Beta-amyloid) is the major constituent of amyloid plaques in the brains of individuals afflicted with Alzheimer's disease
  • Abeta peptide is 40-43 amino acids long and generated from the beta-amyloid precursor protein (beta APP) in a two-step process
  • The first step involves cleavage of the extracellular, amino-terminal domain of beta APP
  • Protein cleavage is performed by an aspartyl protease, beta-secretase (BACE) which is synthesized as a propeptide and must be modified to the mature and active form by the prohormone convertase, furin
  • Beta APP cleavage by the mature form of BACE results in the cellular secretion of a segment of beta APP, and a membrane-bound remnant
  • The remnant protein is processed by another protease, gamma-secretase
  • Gamma-secretase cleaves an intra-membrane site in the carboxyl-terminal domain of beta APP, thus generating the amyloid beta peptide
  • Gamma-secretase is believed to be a multi-subunit complex containing presenilin-1 and 2 as central components
  • The transmembrane glycoprotein, nicastrin, is associated with presinilins and has been found to bind to the carboxyl-terminus of beta APP and helps to modulate the production of the amyloid beta peptide
  • Abeta is an extracellular filamentous protein component of amyloid cores, neuritic plaques and is also found as a deposit in neurofibrillary tangles
  • Alzheimer's disease, the most common cause of senile dementia, is characterized by abnormal filamentous protein deposits in the brain
  • Beta amyloid deposits are also detected in Lewy body dementia, Down's syndrome, amyloidosis (Dutch type), cerebroarterial amyloidosis (cerebral amyloid angiopathy) and in the Guam Parkinson-Dementia complex.

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Show Difference

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Thermo Scientific

PIPA596905

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Antigen:
HSD3B1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
HSD3B1

Gene Alias:
3 beta-hydroxysteroid dehydrogenase 1, 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase, 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1, 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type I, 3BETAHSD, 3-beta-HSD, 3-beta-HSD I, 3-beta-hydroxy-5-ene steroid dehydrogenase, 3-beta-hydroxy-Delta(5)-steroid dehydrogenase, 3-beta-hydroxysteroid 3-dehydrogenase, 3BH, Delta-5-3-ketosteroid isomerase, Dihydrotestosterone oxidoreductase, HGNC:5217, HSD3B, Hsd3b1, HSDB3, HSDB3A, hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1, hydroxy-delta-MAY-steroid dehydrogenase, 3 beta- and steroid delta-isomerase, hydroxysteroid dehydrogenase-1, delta<5>-3-beta, I, Progesterone reductase, SDR11E1, short chain dehydrogenase/reductase family 11E, member 1, steroid Delta-isomerase, Trophoblast antigen FDO161G, unnamed protein product

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
15492, 3283, 360348

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.85 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
P14060, P22071, P24815

Gene Symbols:
HSD3B1

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-290 of human HSD3B1 (NP_0008531)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA596906

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Antigen:
MYLK

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MYLK

Gene Alias:
155 kda myosin light chain kinase homolog, 9530072E15Rik, A clone isolated from a chicken gizzard cDNA library which has high homology with the 3'-end sequence of the chicken gizzard myosin light chain kinase (MLCK) cDNA, The 5'-leader seqeuence derives from the intronic sequence of the MLCK gene., A930019C19Rik, AAT7, AW489456, kinase related protein, kinase-related protein, KRP, KRP/Telokin, MLCK, MLCK1, MLCK108, MLCK210, MSTP083, mylk, MYLK1, myosin light chain kinase, myosin light chain kinase, smooth muscle, Myosin light chain kinase, smooth muscle, deglutamylated form, myosin, light polypeptide kinase, nmMlck, smMLCK, smooth muscle myosin light chain kinase, smooth muscle myosin light chain kinase (61-kDa active fragment), smooth muscle myosin light chain kinase precursor (EC 2.7.2.37), telokin, unnamed protein product

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
107589, 288057, 4638

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.31 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
Q15746, Q6PDN3

Gene Symbols:
MYLK

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1765-1914 of human MYLK (NP_4442533)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA596908

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Antigen:
CCR8

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CCR8

Gene Alias:
C-C, CC chemokine receptor 8, CC chemokine receptor CHEMR1, C-C chemokine receptor type 8, C-C CKR-8, C-C motif chemokine receptor 8, CC-chemokine receptor chemr1, CC-CKR-8, CCR8, CCR-8, cd198, CDw198, chemokine (C-C motif) receptor 8, chemokine (C-C) receptor 8, chemokine (C-C) receptor-like 2, chemokine receptor-like 1, CKR-8, CKRL1, CKR-L1, Cmkbr8, CMKBRL2, CY6, GPRCY6, GPR-CY6, mCCR8, MGC129966, MGC129973, TER1

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12776, 301066

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.8 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
P56484

Gene Symbols:
CCR8

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 296-355 of human CCR8 (NP_0051921)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA596909

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Antigen:
MR1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MR1

Gene Alias:
Class I histocompatibility antigen-like protein, H2ls, histocompatibility-2 complex class 1-like sequence, Hlals, Major histocompatibility complex class I-related gene protein, major histocompatibility complex, class I-like sequence, major histocompatibility complex, class I-related, MCH class I, MHC class I-like antigen MR-1, MHC class I-like sequence, MHC class I-related gene protein, MHC class-I related-gene protein, MR1, Mr1a

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
15064, 25119, 3140

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1.42 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3

Gene Accession No.:
O19477, Q8HWB0, Q95460

Gene Symbols:
MR1

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 23-291 of human MR1 (NP_0015221)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG