PIPA597235
HIC1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA597235-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA597235 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
HIC1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Hic1
Gene Alias
AA408311, HIC1, hic-1, hypermethylated in cancer 1, hypermethylated in cancer 1 protein, ZBTB29, Zinc finger and BTB domain-containing protein 29, ZNF901
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
303310, 3090
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
1.34 mg/mL
Formulation
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.
Q14526
Gene Symbols
Hic1
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 180-430 of human HIC1 (NP_0010916721)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: AATPVIQACY PSPVGPPPPP AAEPPSGPEA AVNTHCAELY ASGPGPAAAL CASERRCSPL CGLDLSKKSP PGSAAPERPL AERELPPRPD SPPSAGPAAY KEPPLALPSL PPLPFQKLEE AAPPSDPFRG GSGSPGPEPP GRPDGPSLLY RWMKHEPGLG SYGDELGRER GSPSERCEER GGDAAVSPGG PPLGLAPPPR YPGSLDGPGA GGDGDDYKSS SEETGSSEDP SPPGGHLEGY PCPHLAYGEP E; Positive Samples: H460, HT-29, DU145, Rat heart; Cellular Location: Nucleus Hypermethylated in cancer (HIC-1) was originally identified as a target of p53-induced gene expression
- HIC-1 is deleted in the genetic disorder Miller-Dieker syndrome (MDS), and the expression of HIC-1 is also frequently suppressed in leukemia and various cancers due to the hypermethylation of specific DNA regions and the resulting transcriptional silencing
- These and other studies indicate that HIC-1 acts as a putative tumor suppressor protein that mediates transcriptional repression
- HIC-1 is ubiquitously expressed in adult tissues and its structure is defined by five zinc fingers and an N-terminal broad complex POZ (or BTB) domain
- In several BTB/POZ containing proteins, including BCL-6 and the promyelocytic leukemia zinc-finger (PLZF) oncoprotein, this domain interacts with the SMRT/N-CoR-mSin3A HDAC complex and is directly involved in repressing and silencing gene transcription
- When this domain is deleted, as with the oncogenic PLZF-RAR chimera of promyelocytic leukemias, this transcriptional repression is attenuated
- Conversely, HIC-1 does not interact with components of the HDAC complex, suggesting that HIC-1-induced transcriptional repression is unassociated with the POZ/BTB domain.
Compare Similar Items
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Antigen: HIC1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Hic1
Gene Alias: AA408311, HIC1, hic-1, hypermethylated in cancer 1, hypermethylated in cancer 1 protein, ZBTB29, Zinc finger and BTB domain-containing protein 29, ZNF901
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 303310, 3090
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 1.34 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.: Q14526
Gene Symbols: Hic1
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 180-430 of human HIC1 (NP_0010916721)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
HIC1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Hic1
Gene Alias:
AA408311, HIC1, hic-1, hypermethylated in cancer 1, hypermethylated in cancer 1 protein, ZBTB29, Zinc finger and BTB domain-containing protein 29, ZNF901
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
303310, 3090
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
1.34 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.:
Q14526
Gene Symbols:
Hic1
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 180-430 of human HIC1 (NP_0010916721)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: TXNDC9
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TXNDC9
Gene Alias: AI098020, APACD, ATP binding protein, ATP binding protein associated with cell differentiation, ATP-binding protein associated with cell differentiation, ES cell-related protein, fb15e07, PHLP3, Protein 1-4, thioredoxin domain containing 9, thioredoxin domain-containing protein 9, TXNDC9, wu:fb15e07, zgc:55522
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 10190, 280671, 98258
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1.53 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.: O14530, Q8K581, Q9CQ79
Gene Symbols: TXNDC9
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human TXNDC9 (NP_0057742)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
TXNDC9
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TXNDC9
Gene Alias:
AI098020, APACD, ATP binding protein, ATP binding protein associated with cell differentiation, ATP-binding protein associated with cell differentiation, ES cell-related protein, fb15e07, PHLP3, Protein 1-4, thioredoxin domain containing 9, thioredoxin domain-containing protein 9, TXNDC9, wu:fb15e07, zgc:55522
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
10190, 280671, 98258
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1.53 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.:
O14530, Q8K581, Q9CQ79
Gene Symbols:
TXNDC9
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human TXNDC9 (NP_0057742)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: EXOSC7
Classification: Polyclonal
Conjugate: Unconjugated
Gene: EXOSC7
Gene Alias: 2610002K22Rik, AV212732, EAP1, EGK_11725, EXOSC7, Exosome complex component RRP42, exosome complex exonuclease RRP42, exosome complex exonuclease RRP42, exosome complex component RRP42, Exosome complex exonuclease RRP42-like protein, exosome component 7, hRrp42p, hypothetical protein LOC550247, KIAA0116, mKIAA0116, p8, Ribosomal RNA-processing protein 42, RRP42, Rrp42p, zgc:110717
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 23016, 316098, 66446
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 1.47 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.: Q15024, Q9D0M0
Gene Symbols: EXOSC7
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-291 of human EXOSC7 (NP_0558192)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
EXOSC7
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
EXOSC7
Gene Alias:
2610002K22Rik, AV212732, EAP1, EGK_11725, EXOSC7, Exosome complex component RRP42, exosome complex exonuclease RRP42, exosome complex exonuclease RRP42, exosome complex component RRP42, Exosome complex exonuclease RRP42-like protein, exosome component 7, hRrp42p, hypothetical protein LOC550247, KIAA0116, mKIAA0116, p8, Ribosomal RNA-processing protein 42, RRP42, Rrp42p, zgc:110717
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
23016, 316098, 66446
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
1.47 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.:
Q15024, Q9D0M0
Gene Symbols:
EXOSC7
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-291 of human EXOSC7 (NP_0558192)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: ADCY1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ADCY1
Gene Alias: 3',5'-cyclic AMP synthetase, Ac1, ADCY1, adenyl cyclase, adenylate cyclase 1, adenylate cyclase 1 (brain), adenylate cyclase type 1, Adenylate cyclase type I, adenylyl cyclase 1, ATP pyrophosphate-lyase 1, barrelless, brl, Ca(2+)/calmodulin-activated adenylyl cyclase, D11Bwg1392e, DFNB44, I-AC, mKIAA4070
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 107, 432530
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.78 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: O88444, Q08828
Gene Symbols: ADCY1
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 470-610 of human ADCY1 (NP_0669391)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
ADCY1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ADCY1
Gene Alias:
3',5'-cyclic AMP synthetase, Ac1, ADCY1, adenyl cyclase, adenylate cyclase 1, adenylate cyclase 1 (brain), adenylate cyclase type 1, Adenylate cyclase type I, adenylyl cyclase 1, ATP pyrophosphate-lyase 1, barrelless, brl, Ca(2+)/calmodulin-activated adenylyl cyclase, D11Bwg1392e, DFNB44, I-AC, mKIAA4070
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
107, 432530
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.78 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
O88444, Q08828
Gene Symbols:
ADCY1
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 470-610 of human ADCY1 (NP_0669391)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG