PIPA597237

EXOSC7 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA597237-Each-of-1 In Stock ₹ 44,705.10

PIPA597237 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

EXOSC7

Classification

Polyclonal

Conjugate

Unconjugated

Gene

EXOSC7

Gene Alias

2610002K22Rik, AV212732, EAP1, EGK_11725, EXOSC7, Exosome complex component RRP42, exosome complex exonuclease RRP42, exosome complex exonuclease RRP42, exosome complex component RRP42, Exosome complex exonuclease RRP42-like protein, exosome component 7, hRrp42p, hypothetical protein LOC550247, KIAA0116, mKIAA0116, p8, Ribosomal RNA-processing protein 42, RRP42, Rrp42p, zgc:110717

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

23016, 316098, 66446

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

1.47 mg/mL

Formulation

PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.

Q15024, Q9D0M0

Gene Symbols

EXOSC7

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-291 of human EXOSC7 (NP_0558192)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: MASVTLSEAE KVYIVHGVQE DLRVDGRGCE DYRCVEVETD VVSNTSGSAR VKLGHTDILV GVKAEMGTPK LEKPNEGYLE FFVDCSASAT PEFEGRGGDD LGTEIANTLY RIFNNKSSVD LKTLCISPRE HCWVLYVDVL LLECGGNLFD AISIAVKAAL FNTRIPRVRV LEDEEGSKDI ELSDDPYDCI RLSVENVPCI VTLCKIGYRH VVDATLQEEA CSLASLLVSV TSKGVVTCMR KVGKGSLDPE SIFEMMETGK RVGKVLHASL QSVVHKEESL GPKRQKVGFL G; Positive Samples: U-87MG, SKOV3, K-562, Jurkat, MCF7, Mouse brain, Rat brain; Cellular Location: Cytoplasm, Nucleus, nucleolus Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events
  • In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm
  • The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates
  • In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs
  • It seems to be involved in degradation of histone mRNA
  • The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9) is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA597237

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Antigen:
EXOSC7

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
EXOSC7

Gene Alias:
2610002K22Rik, AV212732, EAP1, EGK_11725, EXOSC7, Exosome complex component RRP42, exosome complex exonuclease RRP42, exosome complex exonuclease RRP42, exosome complex component RRP42, Exosome complex exonuclease RRP42-like protein, exosome component 7, hRrp42p, hypothetical protein LOC550247, KIAA0116, mKIAA0116, p8, Ribosomal RNA-processing protein 42, RRP42, Rrp42p, zgc:110717

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
23016, 316098, 66446

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1.47 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
Q15024, Q9D0M0

Gene Symbols:
EXOSC7

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-291 of human EXOSC7 (NP_0558192)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA597241

--


Antigen:
ADCY1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ADCY1

Gene Alias:
3',5'-cyclic AMP synthetase, Ac1, ADCY1, adenyl cyclase, adenylate cyclase 1, adenylate cyclase 1 (brain), adenylate cyclase type 1, Adenylate cyclase type I, adenylyl cyclase 1, ATP pyrophosphate-lyase 1, barrelless, brl, Ca(2+)/calmodulin-activated adenylyl cyclase, D11Bwg1392e, DFNB44, I-AC, mKIAA4070

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
107, 432530

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.78 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
O88444, Q08828

Gene Symbols:
ADCY1

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 470-610 of human ADCY1 (NP_0669391)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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PIPA597242

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Antigen:
HLA-DQA2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
__

Gene Alias:
DQ alpha 2, DX ALPHA, DX alpha chain, DX-ALPHA, HLA class II histocompatibility antigen, DQ alpha 2 chain, HLA class II histocompatibility antigen, DQ(6) alpha chain, HLA DXA, HLA-DQA1, HLA-DQA2, HLA-DXA, major histocompatibility complex, class II, DQ alpha 2, MHC class II DQA2

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.95 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 24-125 of human HLA-DQA2 (NP_0644401)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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Thermo Scientific

PIPA597244

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Antigen:
NOXA

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PMAIP1

Gene Alias:
adult T cell leukemia-derived PMA-responsive, APR, Immediate-early-response protein APR, Noxa, Phorbol-12-myristate-13-acetate-induced protein 1, PMA-ind, PMA-induced protein 1, Pmaip1, Protein Noxa

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
492821, 5366, 58801

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
0.88 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
Q13794, Q5U777, Q9JM54

Gene Symbols:
PMAIP1

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-54 of human PMAIP1 (NP_0669501)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG