PIPA597392

Phospho-JAK2 (Tyr1008) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA597392-Each-of-1 In Stock ₹ 44,705.10

PIPA597392 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

Phospho-JAK2 (Tyr1008)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

JAK2

Gene Alias

EC 2.7.10.2, Fd17, JAK 2, JAK2, JAK-2, Janus kinase 2, Janus kinase 2 (a protein tyrosine kinase), JTK 10, JTK10, kinase Jak2, THCYT3, Tyrosine-protein kinase JAK2

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3717

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

0.66 mg/mL

Formulation

PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.

O60674

Gene Symbols

JAK2

Immunogen

A synthetic phosphorylated peptide around Y1008 of human Phospho-JAK2-Y1008 (NP_0049631)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: EYYKV; Positive Samples: Jurkat; Cellular Location: Cytoplasm, Endomembrane system, Nucleus, Peripheral membrane protein Janus kinase 2 (JAK2) is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways and is mutated in polycythemia vera
  • This kinase contains the catalytic domain (JH1) of JAK2
  • The activation of JAKs can lead to the phosphorylation of STAT (signal transducers and activatiors of transcription) proteins, which dimerize and translocate to the nucleus
  • Once translocated to the nucleus, the STAT proteins can modify transcription of numerous genes, including interferon-stimulated genes
  • JAK2 is required for the IFN gamma-receptor complex initiation and JAK1 functions as an amplifier
  • Some studies have suggested that the role of JAK2 might be performed by Tyk2 and JAK3, if they were positioned correctly within the IFN gamma-receptor complex
  • Mutations affecting JAK2 can cause Budd-Chiari syndrome, Polycythemia vera, Thrombocythemia 3, myelofibrosis, or Acute myelogenous leukemia.

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Img

Thermo Scientific

PIPA597392

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Antigen:
Phospho-JAK2 (Tyr1008)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
JAK2

Gene Alias:
EC 2.7.10.2, Fd17, JAK 2, JAK2, JAK-2, Janus kinase 2, Janus kinase 2 (a protein tyrosine kinase), JTK 10, JTK10, kinase Jak2, THCYT3, Tyrosine-protein kinase JAK2

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3717

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.66 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
O60674

Gene Symbols:
JAK2

Immunogen:
A synthetic phosphorylated peptide around Y1008 of human Phospho-JAK2-Y1008 (NP_0049631)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA597393

--


Antigen:
Phospho-eIF4B (Ser422)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Eif4b

Gene Alias:
2310046H11Rik, AL024095, C85189, Eif4a2, EIF4B, eIF-4B, Eukaryotic translation initiation factor 4B, hCG_2014609, hypothetical protein, PRO1843

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1975

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.2 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
P23588

Gene Symbols:
Eif4b

Immunogen:
A synthetic phosphorylated peptide around S422 of human EIF4B (NP_0014082)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA597394

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Antigen:
Phospho-Lamin A/C (Ser22)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
LMNA

Gene Alias:
70 kDa lamin, cb948, CDCD1, CDDC, CMD1A, CMT2B1, Dhe, EMD2, FPL, FPLD, FPLD2, HGPS, I79_009616, IDC, lamin, lamin A, lamin A/C, lamin A/C L homeolog, lamin A/C-like 1, Lamin A+C mutant, Lamin AC, lamin a-c, lamin C, lamin C2, lamin-A, Lamin-A/C, LDP1, LFP, LGMD1B, LMN1, lmna, LMNA protein, lmna.L, lmna-A, LMNC, LMNL1, mutant 453W, Mutant lamin A/C, nuclear intermediate filament protein, nuclear lamin A, prelamin-A/C, PRO1, progerin mutant, Renal carcinoma antigen NY-REN-32, RP11-54H19.1, unnamed protein product, wu:fk66d12, XELAEV_18040808mg

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4000, 60374

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunoprecipitation, Western Blot

Concentration:
0.43 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
P02545, P48679

Gene Symbols:
LMNA

Immunogen:
A synthetic phosphorylated peptide around S22 of human Lamin A (NP_0055631)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA597395

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Antigen:
Phospho-ATP Citrate Lyase (Ser455)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Acly

Gene Alias:
17-beta-HSD 10, 17-beta-hydroxysteroid dehydrogenase 10, 17bHSD10, 17b-HSD10, 2-methyl-3-hydroxybutyryl-CoA dehydrogenase, 3-hydroxy-2-methylbutyryl-CoA dehydrogenase, 3-hydroxyacyl-CoA dehydrogenase type II, 3-hydroxyacyl-CoA dehydrogenase type-2, A730098H14Rik, ABAD, AB-binding alcohol dehydrogenase, ACL, ACLY, Ads9, amyloid beta-peptide binding protein, amyloid-beta peptide binding alcohol dehydrogenase, ATP citrate lyase, ATP-citrate (pro-S-)-lyase, ATP-citrate synthase, ATPCL, AW538652, CAMR, citrate cleavage enzyme, CLATP, DUPXp11.22, endoplasmic reticulum-associated amyloid beta-peptide-binding protein, ERAB, HADH2, HCD2, Hsd17b10, hydroxyacyl-Coenzyme A dehydrogenase type II, hydroxyacyl-Coenzyme A dehydrogenase, type II, hydroxysteroid (17-beta) dehydrogenase 10, hydroxysteroid 17-beta dehydrogenase 10, hydroxysteroid dehydrogenase 10, MHBD, Mitochondrial ribonuclease P protein 2, mitochondrial RNase P protein 2, mitochondrial RNase P subunit 2, MRPP2, MRX17, MRX31, MRXS10, SCHAD, SDR5C1, short chain dehydrogenase/reductase family 5C member 1, short chain dehydrogenase/reductase family 5C, member 1, short chain L-3-hydroxyacyl-CoA dehydrogenase, short chain L-3-hydroxyacyl-CoA dehydrogenase type 2, short chain type dehydrogenase/reductase XH98G2, Short-chain type dehydrogenase/reductase XH98G2, Type II HADH, XH98G2

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
104112, 24159

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
1.12 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
P16638, Q91V92

Gene Symbols:
Acly

Immunogen:
A synthetic phosphorylated peptide around S455 of human ACLY (NP_0010872)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Product Type:
Antibody

Isotype:
IgG