PIPA597377

Phospho-CDK4 (Thr172) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA597377-Each-of-1 In Stock ₹ 45,218.46

PIPA597377 - Each of 1

₹ 45,218.46

In Stock

Quantity

1

Base Price: ₹ 45,218.46

GST (18%): ₹ 8,139.323

Total Price: ₹ 53,357.783

Antigen

Phospho-CDK4 (Thr172)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Cdk4

Gene Alias

Cdk4, Cell division protein kinase 4, CMM3, Crk3, cyclin dependent kinase 4, cyclin-dependent kinase 4, MGC14458, p34<PSK-J3>/cdk4, PSK-J3, serine/threonine kinase, Unknown (protein for MGC:133903)

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

1019, 12567, 94201

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

1.21 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.

P11802, P30285, P35426

Gene Symbols

Cdk4

Immunogen

A synthetic phosphorylated peptide around T172 of human CDK4 (NP_0000661)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Positive Samples: HCT116; Cellular Location: Cytoplasm, Membrane, Nucleus Immunogen sequence: ALTPVV CDK4/cyclin D3 serine/threonine kinase is dimeric protein complex
  • CDK4 is a member of the cyclin-dependent protein kinase family and is involved in the control of cell proliferation during the G1 phase of cell cycle
  • CDK4 forms a complex with the D-type cyclins and is inhibited by p16 (cyclin-dependent kinase inhibitor-2)
  • CDK4 can mediate phosphorylation of the C-terminal region of Rb protein leading to an active transcriptional repression of E2F complex
  • CDC37 and HSP90 can preferentially associate with the fraction of CDK4 not bound to D-type cyclins
  • SMAD3 is a major physiologic substrate of the G1 cyclin-dependent kinases CDK4 and CDK2
  • Although CDK6 and CDK4 can both phosphorylate multiple residues in the Rb protein, they do so with different residue selectivity in vitro; CDK6 phosphorylates Thr821 while CDK4 phosphorylates Thr826 on Rb protein.

Compare Similar Items

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Img

Thermo Scientific

PIPA597377

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Antigen:
Phospho-CDK4 (Thr172)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Cdk4

Gene Alias:
Cdk4, Cell division protein kinase 4, CMM3, Crk3, cyclin dependent kinase 4, cyclin-dependent kinase 4, MGC14458, p34<PSK-J3>/cdk4, PSK-J3, serine/threonine kinase, Unknown (protein for MGC:133903)

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1019, 12567, 94201

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1.21 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
P11802, P30285, P35426

Gene Symbols:
Cdk4

Immunogen:
A synthetic phosphorylated peptide around T172 of human CDK4 (NP_0000661)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA597378

--


Antigen:
Phospho-AMPK beta-1 (Ser108)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PRKAB1

Gene Alias:
1300015D22Rik, 5'-AMP-activated protein kinase 40 kDa subunit, 5-AMP-activated protein kinase beta subunit, 5'-AMP-activated protein kinase beta-1 subunit, 5'-AMP-activated protein kinase subunit beta-1, 5'-AMP-activated protein kinase subunit beta-1-like protein, 5'-AMP-activated protein kinase, beta subunit, AAKB1, AMP-activated protein kinase beta subunit, AMPK, AMPK beta 1, AMPK beta -1 chain, AMPK beta-1 chain, AMPK subunit beta-1, AMPKb, AMPK-beta1, AU021155, E430008F22, HAMPKb, kinase AMPK-beta1, kinase pAMPK, pAMPK, Prkab1, protein kinase AMP-activated non-catalytic subunit beta 1, protein kinase, AMP-activated, beta 1 non-catalytic subunit, protein kinase, AMP-activated, noncatalytic, beta-1

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5564

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
Q9Y478

Gene Symbols:
PRKAB1

Immunogen:
A synthetic phosphorylated peptide around S108 of human AMPKbeta1 (NP_0062442)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA597379

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Antigen:
Phospho-FAK (Tyr925)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PTK2

Gene Alias:
CG10023, CG10023-PA, CG10023-PB, CG10023-PC, CG10023-PD, CG10023-PF, CG10023-PG, CT28129, DFAK, DFak56, Dmel\CG10023, Dmel_CG10023, DmFAK, EC 2.7.10.2, Fadk, FADK 1, Fak, Fak1, Fak56, fak56D, FAK65D, Fak-PA, Fak-PB, Fak-PC, Fak-PD, Fak-PF, Fak-PG, FAK-related non-kinase polypeptide, focal adhesion kinase, Focal adhesion kinase 1, focal adhesion kinase homolog, focal adhesion kinase isoform FAK-Del33, focal adhesion kinase pp125FAK, focal adhesion kinase-related nonkinase, focal ashension kinase 1, FRNK, I79_019430, Kiaa4203, mKIAA4203, p125FAK, p41/p43FRNK, pFAK, pp125 PTK2, pp125FAK, PPP1R71, Protein phosphatase 1 regulatory subunit 71, protein phosphatase 1, regulatory subunit 71, protein tyrosine kinase 2, protein tyrosine kinase 2 L homeolog, protein-tyrosine kinase, protein-tyrosine kinase 2, PTK2, PTK2 protein tyrosine kinase 2, ptk2.L, tyrosine kinase, XELAEV_18032408mg, XPFAK

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5747

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.41 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
Q05397

Gene Symbols:
PTK2

Immunogen:
A synthetic phosphorylated peptide around Y925 of human FAK (NP_7225601)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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Thermo Scientific

PIPA597380

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Antigen:
Phospho-LKB1 (Ser428)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
STK11

Gene Alias:
AA408040, CAMK group, CAMKL family, hLKB1, liver kinase B1, Liver kinase B1 homolog, LKB 1, LKB1, LKB-1, LKB1(S), Par-4, PJS, polarization-related protein LKB1, R75140, renal carcinoma antigen NY-REN-19, serine/threonine kinase 11, serine/threonine-protein kinase 11, serine/threonine-protein kinase LKB1, serine/threonine-protein kinase STK11, STK11

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20869, 314621, 6794

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.34 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
D4AE59, Q15831, Q9WTK7

Gene Symbols:
STK11

Immunogen:
A synthetic phosphorylated peptide around S428 of human STK11 (NP_0004461)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG