PIPA598950

FICD Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA598950-Each-of-1 In Stock ₹ 44,277.30

PIPA598950 - Each of 1

₹ 44,277.30

In Stock

Quantity

1

Base Price: ₹ 44,277.30

GST (18%): ₹ 7,969.914

Total Price: ₹ 52,247.214

Antigen

FICD

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Ficd

Gene Alias

adenosine monophosphate-protein transferase FICD; AMPylator FICD; D5Ertd40e; De-AMPylase FICD; FIC domain containing; FIC domain protein adenylyltransferase; FIC domain-containing protein; fic S-phase protein cell division homolog; FICD; HIP13; HIP-13; huntingtin interacting protein 13; huntingtin interacting protein E; huntingtin interactor protein E; huntingtin yeast partner E; Huntingtin-interacting protein 13; huntingtin-interacting protein E; Hype; MGC5623; Protein adenylyltransferase FICD; protein adenylyltransferase FICD; adenosine monophosphate-protein transferase FICD; UNQ3041; UNQ3041/PRO9857

Host Species

Rabbit

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

11153, 288741

Content And Storage

-20°C or -80°C if preferred

Form

Liquid

Applications

ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

3.06 mg/mL

Formulation

PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4

Gene Accession No.

Q6AY47, Q9BVA6

Gene Symbols

Ficd

Immunogen

Recombinant Human Adenosine monophosphate-protein transferase FICD protein (63-185AA)

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Protein that can both mediate the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins (AMPylation), and the removal of the same modification from target proteins (de-AMPylation), depending on the context
  • The side chain of Glu-231 determines which of the two opposing activities (AMPylase or de-AMPylase) will take place
  • Acts as a key regulator of the ERN1/IRE1-mediated unfolded protein response (UPR) by mediating AMPylation or de-AMPylation of HSPA5/BiP (PubMed:25601083)
  • In unstressed cells, acts as an adenylyltransferase by mediating AMPylation of HSPA5/BiP at 'Thr-518', thereby inactivating it
  • In response to endoplasmic reticulum stress, acts as a phosphodiesterase by mediating removal of ATP (de-AMPylation) from HSPA5/BiP at 'Thr-518', leading to restore HSPA5/BiP activity
  • Although it is able to AMPylate RhoA, Rac and Cdc42 Rho GTPases in vitro, Rho GTPases do not constitute physiological substrates (PubMed:19362538, PubMed:25601083)
  • [UniProt]

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA598950

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Antigen:
FICD

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Ficd

Gene Alias:
adenosine monophosphate-protein transferase FICD; AMPylator FICD; D5Ertd40e; De-AMPylase FICD; FIC domain containing; FIC domain protein adenylyltransferase; FIC domain-containing protein; fic S-phase protein cell division homolog; FICD; HIP13; HIP-13; huntingtin interacting protein 13; huntingtin interacting protein E; huntingtin interactor protein E; huntingtin yeast partner E; Huntingtin-interacting protein 13; huntingtin-interacting protein E; Hype; MGC5623; Protein adenylyltransferase FICD; protein adenylyltransferase FICD; adenosine monophosphate-protein transferase FICD; UNQ3041; UNQ3041/PRO9857

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
11153, 288741

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
3.06 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4

Gene Accession No.:
Q6AY47, Q9BVA6

Gene Symbols:
Ficd

Immunogen:
Recombinant Human Adenosine monophosphate-protein transferase FICD protein (63-185AA)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG

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Thermo Scientific

PIPA598952

--


Antigen:
BARHL1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
BARHL1

Gene Alias:
Bar-class homeodomain protein MBH2; BarH like homeobox 1; BARHL1; Barhl2; BarH-like 1 (Drosophila); barH-like 1 homeobox protein; BarH-like 2; BarH-like homeobox 1; barH-related homeobox protein 1; Bhx1; Dres115; FKSG31; Mbh2; PKCdeltaVIII

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
56751

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot

Concentration:
4.27 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4

Gene Accession No.:
Q9BZE3

Gene Symbols:
BARHL1

Immunogen:
Recombinant Human BarH-like 1 homeobox protein (38-176AA)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA598953

--


Antigen:
CEP44

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CEP44

Gene Alias:
4933440G23Rik; centrosomal protein 44; centrosomal protein 44kDa; centrosomal protein of 44 kDa; Cep44; HBV PreS1-transactivated protein 3; KIAA1712; mKIAA1712; PS1TP3

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
80817

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.76 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q9C0F1

Gene Symbols:
CEP44

Immunogen:
Recombinant Human Centrosomal protein of 44 kDa protein (1-280AA)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA598954

--


Antigen:
ALS2CR1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NIF3L1

Gene Alias:
1110030G24Rik; ALS2CR1; amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 1; amyotrophic lateral sclerosis 2 chromosomal region candidate gene 1 protein; CALS-7; GTP cyclohydrolase I; MDS015; My018; Ngg1 interacting factor 3 homolog-like 1; NGG1 interacting factor 3 like 1; Ngg1 interacting factor 3-like 1; Ngg1 interacting factor 3-like 1 (S. pombe); NIF3 (Ngg1 interacting factor 3, S.pombe homolog)-like 1; NIF3 NGG1 interacting factor 3-like 1; NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae); Nif3l1; NIF3-like protein 1; OTTHUMP00000206190; OTTHUMP00000206191; OTTHUMP00000206192; putative GTP cyclohydrolase 1 type 2 Nif3l1

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
60491

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot

Concentration:
5 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4

Gene Accession No.:
Q9GZT8

Gene Symbols:
NIF3L1

Immunogen:
Recombinant Human NIF3-like protein 1 protein (1-377AA)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG