PIPA599217

MUTYH Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA599217-Each-of-1 In Stock ₹ 44,705.10

PIPA599217 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

MUTYH

Classification

Polyclonal

Conjugate

Unconjugated

Gene

MUTYH

Gene Alias

5730495A01Rik; A/G-specific adenine DNA glycosylase; adenine DNA glycosylase; adenine-DNA glycosylase; hMYH; MGC4416; mMYH; mutY DNA glycosylase; mutY homolog; mutY homolog (E. coli); mutY homolog alpha; Mutyh; Mutyha; Mutyhalpha; Mutyhb; Mutyhbeta; Mutyhc; mutY-like protein; Myh; OTTHUMP00000009098; OTTHUMP00000009102; rMYH; RP4-534D1.2; the full-length form type A, 5' region

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

170841, 4595, 70603

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q8R5G2, Q99P21, Q9UIF7

Gene Symbols

MUTYH

Immunogen

A synthesized peptide derived from human MUTYH(Accession Q9UIF7), corresponding to amino acid residues L156-Q206.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total MUTYH
  • MYH (mutY homolog (E
  • coli )) is a DNA glycosylase mismatch repair enzyme that in conjunction with mutM (OGG1), cleaves adenine residues paired with either oxidized (8-hydroxyguanines) or non-modified guanines in order to correct A/G and A/C mismatches
  • Repair of most modified and mispaired bases in the genome is initiated by DNA glycosylases, which bind and cleave N-glycosyl bonds to initiate base excision repair
  • MYH is crucial for the avoidance of mutations resulting from oxidative DNA damage
  • Multiple N-terminal splice variants of MYH exist in mammalian cells
  • Increasing levels of MYH in A549 cells exposed to oxygen and infrared radiation leads to improvements in cell survival
  • Biallelic MYH germ-line mutations predispose humans to colorectal adenomas and carcinomas
  • MYH is abundant in neurons where mitochondrial genomes exposed to reactive oxygen species (ROS) that damage DNA must maintain integrity over the entire mammalian life span.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA599217

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Antigen:
MUTYH

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MUTYH

Gene Alias:
5730495A01Rik; A/G-specific adenine DNA glycosylase; adenine DNA glycosylase; adenine-DNA glycosylase; hMYH; MGC4416; mMYH; mutY DNA glycosylase; mutY homolog; mutY homolog (E. coli); mutY homolog alpha; Mutyh; Mutyha; Mutyhalpha; Mutyhb; Mutyhbeta; Mutyhc; mutY-like protein; Myh; OTTHUMP00000009098; OTTHUMP00000009102; rMYH; RP4-534D1.2; the full-length form type A, 5' region

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
170841, 4595, 70603

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q8R5G2, Q99P21, Q9UIF7

Gene Symbols:
MUTYH

Immunogen:
A synthesized peptide derived from human MUTYH(Accession Q9UIF7), corresponding to amino acid residues L156-Q206.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA599218

--


Antigen:
ABCF1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Abcf1

Gene Alias:
ABC27; ABC50; ABCF1; ATP binding cassette subfamily F member 1; ATP-binding cassette 50; ATP-binding cassette 50 (TNF-alpha stimulated); ATP-binding cassette sub-family F member 1; ATP-binding cassette sub-family F member 1; LOW QUALITY PROTEIN: ATP-binding cassette sub-family F member 1; ATP-binding cassette, subfamily F (GCN20), member 1; ATP-binding cassette, sub-family F (GCN20), member 1; ATP-binding cassette, sub-family F, member 1; AU041969; D17Wsu166e; GCN20; TNF-alpha stimulated ABC protein; TNFalpha-inducible ATP-binding protein; TNF-alpha-stimulated ABC protein; wu:fb79c06; wu:fc39a05; wu:fj94a08; zgc:85667

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
224742, 23, 85493

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q6MG08, Q6P542, Q8NE71

Gene Symbols:
Abcf1

Immunogen:
A synthesized peptide derived from human ABCF1(Accession Q8NE71), corresponding to amino acid residues R800-E845.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA599219

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Antigen:
PTPN22

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Ptpn22

Gene Alias:
70zpep; Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP; Lymphoid phosphatase; lymphoid-specific protein tyrosine phosphatase; LyP; LYP1; LYP2; PEP; PEST domain-enriched tyrosine phosphatase; PEST-domain phosphatase; protein tyrosine phosphatase, non-receptor type 22; protein tyrosine phosphatase, non-receptor type 22 (lymphoid); protein tyrosine phosphatase, non-receptor type 8; Ptpn22; PTPN8; tyrosine-phosphatase; Tyrosine-protein phosphatase non-receptor type 22

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
19260, 26191, 295338

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P29352, Q9Y2R2

Gene Symbols:
Ptpn22

Immunogen:
A synthesized peptide derived from human PTPN22(Accession Q9Y2R2), corresponding to amino acid residues K770-I807.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA599220

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Antigen:
CIB3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CIB3

Gene Alias:
C730014M21Rik; calcium and integrin binding family member 3; calcium and integrin-binding family member 3; CIB3; DNA-dependent protein kinase catalytic subunit-interacting protein 3; Gm1107; Kinase-interacting protein 3; KIP 3; KIP3

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
117286, 234421

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q0P523, Q96Q77

Gene Symbols:
CIB3

Immunogen:
A synthesized peptide derived from human CIB3(Accession Q96Q77), corresponding to amino acid residues R137-I187.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG