PIPA599823

IL31RA Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA599823-Each-of-1 In Stock ₹ 44,705.10

PIPA599823 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

IL31RA

Classification

Polyclonal

Conjugate

Unconjugated

Gene

IL31RA

Gene Alias

class I cytokine receptor; CRL; CRL 3; CRL3; CRL3Glmr; cytokine receptor NR10; cytokine receptor-like 3; GLM R; Glmr; GLM-R; GLM-RMGC125346; GP130 like receptor; gp130-like monocyte receptor; Gp130-like receptor; GPL; HGLM R; HGLMR; hGLM-R; IL 31RA; IL-31 receptor subunit alpha; IL31R subunit alpha; IL-31R subunit alpha; Il31ra; IL-31RA; IL-31RAGPLCRL; IL-31R-alpha; interleukin 31 receptor A; interleukin 31RA; interleukin-31 receptor subunit alpha; MGC125346; mGLM-R; novel cytokine receptor 10; NR10; PLCA 2; PLCA2; PRO21384; soluble type I cytokine receptor CRL3; UNQ6368/PRO21073/PRO21384; ZcytoR17

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

133396

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q8NI17

Gene Symbols

IL31RA

Immunogen

A synthesized peptide derived from human IL31RA(Accession Q8NI17), corresponding to amino acid residues K548-T598.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total IL31R
  • IL-31 is a T cell cytokine that is preferentially produced by T helper type 2 cells
  • IL-31 signals through a heterodimeric receptor composed of the IL-31 receptor (IL-31R) and the oncostatin M receptor (OSM)
  • This receptor complex recruits JAK1, JAK2, Stat1, Stat3 and Stat5 signaling pathways, as well as the PI3 kinase/AKT cascade
  • SHP-2 and Shc adapter molecules are also recruited and contribute to an increased activation of the MAP kinase pathway in response to IL-31
  • Overexpression of IL-31 in mice results in pruritus and skin dermatitis resembling human atopic dermatitis (AD)
  • Comparisons between skin from patients with AD and healthy skin showed IL-31R expression at higher levels on epidermal keratinocytes in AD samples
  • Infiltrating cells, more numerous in skin from patients with AD compared with that of healthy individuals, expressed IL-31 mRNA
  • IL-31 may participate in the cause of itch sensation and promote scratching behavior in NC/Nga mice with atopic dermatitis, and may represent a novel target for antipruritic drug development.

Compare Similar Items

Show Difference

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PIPA599823

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Antigen:
IL31RA

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IL31RA

Gene Alias:
class I cytokine receptor; CRL; CRL 3; CRL3; CRL3Glmr; cytokine receptor NR10; cytokine receptor-like 3; GLM R; Glmr; GLM-R; GLM-RMGC125346; GP130 like receptor; gp130-like monocyte receptor; Gp130-like receptor; GPL; HGLM R; HGLMR; hGLM-R; IL 31RA; IL-31 receptor subunit alpha; IL31R subunit alpha; IL-31R subunit alpha; Il31ra; IL-31RA; IL-31RAGPLCRL; IL-31R-alpha; interleukin 31 receptor A; interleukin 31RA; interleukin-31 receptor subunit alpha; MGC125346; mGLM-R; novel cytokine receptor 10; NR10; PLCA 2; PLCA2; PRO21384; soluble type I cytokine receptor CRL3; UNQ6368/PRO21073/PRO21384; ZcytoR17

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
133396

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q8NI17

Gene Symbols:
IL31RA

Immunogen:
A synthesized peptide derived from human IL31RA(Accession Q8NI17), corresponding to amino acid residues K548-T598.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA599825

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Antigen:
KRT84

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
KRT84

Gene Alias:
65 kDa type II keratin; AV235125; hard keratin, type II, 4; HB4; HRb-1; K84; Kb24; keratin 84; keratin 84, type II; keratin complex 2, basic, gene 16; keratin complex 2, gene 16; keratin, hair, basic, 4; keratin, type II cuticular Hb4; Keratin-84; Krt2-16; Krt2-3; Krt84; KRTHB4; type II hair keratin 4; type II hair keratin Hb4; type II keratin Kb24; type-II keratin Kb24

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16680, 315320, 3890

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q99M73, Q9NSB2

Gene Symbols:
KRT84

Immunogen:
A synthesized peptide derived from human KRT84(Accession Q9NSB2), corresponding to amino acid residues G550-Y600.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA599826

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Antigen:
XCL1/XCL2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
XCL1

Gene Alias:
AI661682; ATAC; C motif chemokine 1; c motif chemokine 2; chemokine (C motif) ligand 1; chemokine (C motif) ligand 2; cytokine SCM-1; Cytokine SCM-1 beta; Lptn; LTN; Lymphotactin; lymphotaxin; SCM1; SCM-1; SCM1A; SCM-1a; SCM-1-alpha; SCM1B; SCM-1b; Scyc1; SCYC2; single cysteine motif 1a; small inducible cytokine subfamily C, member 1 (lymphotactin); small inducible cytokine subfamily C, member 2; small-inducible cytokine C1; XC chemokine ligand 1; XC chemokine ligand 2; X-C motif chemokine ligand 1; X-C motif chemokine ligand 2; Xcl1; XCL2

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16963, 6375, 6846

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P47992, P47993, Q9UBD3

Gene Symbols:
XCL1, XCL2

Immunogen:
A synthesized peptide derived from human XCL2(Accession Q9UBD3), corresponding to amino acid residues F60-V110.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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PIPA599827

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Antigen:
Cyclin B3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CCNB3

Gene Alias:
CCNB3; CYCB3; cyclin B3; CyclinB3; G2/mitotic-specific cyclin-B3; Protein Ccnb3; RGD1564367

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
85417

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q8WWL7

Gene Symbols:
CCNB3

Immunogen:
A synthesized peptide derived from human CCNB3(Accession Q8WWL7), corresponding to amino acid residues P6-A56.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG