PIPA599937
HCAR2/HCAR3 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA599937-Each-of-1 | In Stock | ₹ 39,999.30 |
PIPA599937 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 39,999.30
GST (18%): ₹ 7,199.874
Total Price: ₹ 47,199.174
Antigen
HCAR2/HCAR3
Classification
Polyclonal
Conjugate
Unconjugated
Gene
HCAR3
Gene Alias
G protein-coupled receptor 109A; G protein-coupled receptor 109B; G protein-coupled receptor HM74a; GPR109A; GPR109B; G-protein coupled receptor 109A; G-protein coupled receptor 109B; G-protein coupled receptor HM74; G-protein coupled receptor HM74A; G-protein coupled receptor HM74B; GTP-binding protein; HCA2; HCA3; HCAR2; HCAR3; HM74; HM74a; HM74B; hydroxycarboxylic acid receptor 2; hydroxy-carboxylic acid receptor 2; Hydroxycarboxylic acid receptor 3; hydroxy-carboxylic acid receptor 3; niacin receptor 1; Niacin receptor 2; NIACR1; NIACR2; Nicotinic acid receptor; nicotinic acid receptor 2; PUMAG; Puma-g; putative chemokine receptor
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
338442, 8843
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
P49019, Q8TDS4
Gene Symbols
HCAR2, HCAR3
Immunogen
A synthesized peptide derived from human HCAR2(Accession Q8TDS4), corresponding to amino acid residues F304-S354.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of total GPR109A/B
- Acts as a high affinity receptor for both nicotinic acid (also known as niacin) and (D)-beta-hydroxybutyrate and mediates increased adiponectin secretion and decreased lipolysis through G(i)-protein-mediated inhibition of adenylyl cyclase
- This pharmacological effect requires nicotinic acid doses that are much higher than those provided by a normal diet
- Mediates nicotinic acid-induced apoptosis in mature neutrophils
- Receptor activation by nicotinic acid results in reduced cAMP levels which may affect activity of cAMP-dependent protein kinase A and phosphorylation of target proteins, leading to neutrophil apoptosis
- The rank order of potency for the displacement of nicotinic acid binding is 5-methyl pyrazole-3-carboxylic acid = pyridine-3-acetic acid > acifran > 5-methyl nicotinic acid = acipimox >> nicotinuric acid = nicotinamide.
Compare Similar Items
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Antigen: HCAR2/HCAR3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: HCAR3
Gene Alias: G protein-coupled receptor 109A; G protein-coupled receptor 109B; G protein-coupled receptor HM74a; GPR109A; GPR109B; G-protein coupled receptor 109A; G-protein coupled receptor 109B; G-protein coupled receptor HM74; G-protein coupled receptor HM74A; G-protein coupled receptor HM74B; GTP-binding protein; HCA2; HCA3; HCAR2; HCAR3; HM74; HM74a; HM74B; hydroxycarboxylic acid receptor 2; hydroxy-carboxylic acid receptor 2; Hydroxycarboxylic acid receptor 3; hydroxy-carboxylic acid receptor 3; niacin receptor 1; Niacin receptor 2; NIACR1; NIACR2; Nicotinic acid receptor; nicotinic acid receptor 2; PUMAG; Puma-g; putative chemokine receptor
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 338442, 8843
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P49019, Q8TDS4
Gene Symbols: HCAR2, HCAR3
Immunogen: A synthesized peptide derived from human HCAR2(Accession Q8TDS4), corresponding to amino acid residues F304-S354.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
HCAR2/HCAR3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
HCAR3
Gene Alias:
G protein-coupled receptor 109A; G protein-coupled receptor 109B; G protein-coupled receptor HM74a; GPR109A; GPR109B; G-protein coupled receptor 109A; G-protein coupled receptor 109B; G-protein coupled receptor HM74; G-protein coupled receptor HM74A; G-protein coupled receptor HM74B; GTP-binding protein; HCA2; HCA3; HCAR2; HCAR3; HM74; HM74a; HM74B; hydroxycarboxylic acid receptor 2; hydroxy-carboxylic acid receptor 2; Hydroxycarboxylic acid receptor 3; hydroxy-carboxylic acid receptor 3; niacin receptor 1; Niacin receptor 2; NIACR1; NIACR2; Nicotinic acid receptor; nicotinic acid receptor 2; PUMAG; Puma-g; putative chemokine receptor
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
338442, 8843
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P49019, Q8TDS4
Gene Symbols:
HCAR2, HCAR3
Immunogen:
A synthesized peptide derived from human HCAR2(Accession Q8TDS4), corresponding to amino acid residues F304-S354.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: OR52H1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: OR52H1
Gene Alias: Olfactory receptor 52H1; olfactory receptor family 52 subfamily H member 1; olfactory receptor OR11-41 pseudogene; olfactory receptor OR11-45; olfactory receptor, family 52, subfamily H, member 1; OR11-41; OR11-45; OR52H1
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 390067
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q8NGJ2
Gene Symbols: OR52H1
Immunogen: A synthesized peptide derived from human OR52H1(Accession Q8NGJ2), corresponding to amino acid residues V215-F265.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
OR52H1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
OR52H1
Gene Alias:
Olfactory receptor 52H1; olfactory receptor family 52 subfamily H member 1; olfactory receptor OR11-41 pseudogene; olfactory receptor OR11-45; olfactory receptor, family 52, subfamily H, member 1; OR11-41; OR11-45; OR52H1
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
390067
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q8NGJ2
Gene Symbols:
OR52H1
Immunogen:
A synthesized peptide derived from human OR52H1(Accession Q8NGJ2), corresponding to amino acid residues V215-F265.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: OR52K2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: OR52K2
Gene Alias: Olfactory receptor 52K2; olfactory receptor family 52 subfamily K member 2; olfactory receptor OR11-7; olfactory receptor, family 52, subfamily K, member 2; OR11-7; OR52K2
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 119774
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q8NGK3
Gene Symbols: OR52K2
Immunogen: A synthesized peptide derived from human OR52K2(Accession Q8NGK3), corresponding to amino acid residues A66-V116.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
OR52K2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
OR52K2
Gene Alias:
Olfactory receptor 52K2; olfactory receptor family 52 subfamily K member 2; olfactory receptor OR11-7; olfactory receptor, family 52, subfamily K, member 2; OR11-7; OR52K2
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
119774
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q8NGK3
Gene Symbols:
OR52K2
Immunogen:
A synthesized peptide derived from human OR52K2(Accession Q8NGK3), corresponding to amino acid residues A66-V116.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: OR52L2P
Classification: Polyclonal
Conjugate: Unconjugated
Gene: OR52L2P
Gene Alias: __
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 79274
Content And Storage: -20°C
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q8NGH6
Gene Symbols: OR52L2P
Immunogen: A synthesized peptide derived from human OR52L2P(Accession Q8NGH6), corresponding to amino acid residues L223-G273.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
OR52L2P
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
OR52L2P
Gene Alias:
__
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
79274
Content And Storage:
-20°C
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q8NGH6
Gene Symbols:
OR52L2P
Immunogen:
A synthesized peptide derived from human OR52L2P(Accession Q8NGH6), corresponding to amino acid residues L223-G273.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG