PIPA599964

SHARPIN Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA599964-Each-of-1 In Stock ₹ 44,705.10

PIPA599964 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

SHARPIN

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SHARPIN

Gene Alias

0610041B22Rik; AW121341; Conneck1; cpdm; hSIPL1; mSIPL1; protein kinase C-interacting protein RBCC like 1; PSEC0216; RBCKL1; SHANK associated RH domain interactor; SHANK-associated RH domain interacting protein; SHANK-associated RH domain interactor; shank-associated RH domain-interacting protein; shank-interacting protein; shank-interacting protein-like 1; SHARPIN; SIPL1

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

106025, 81858, 81859

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q91WA6, Q9EQL9, Q9H0F6

Gene Symbols

SHARPIN

Immunogen

A synthesized peptide derived from human SHARPIN(Accession Q9H0F6), corresponding to amino acid residues G66-V116.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total SHARPIN
  • Component of the LUBAC complex which conjugates linear polyubiquitin chains in a head-to-tail manner to substrates and plays a key role in NF-kappa-B activation and regulation of inflammation
  • LUBAC conjugates linear polyubiquitin to IKBKG and RIPK1 and is involved in activation of the canonical NF-kappa-B and the JNK signaling pathways
  • Linear ubiquitination mediated by the LUBAC complex interferes with TNF-induced cell death and thereby prevents inflammation
  • LUBAC is proposed to be recruited to the TNF-R1 signaling complex (TNF-RSC) following polyubiquitination of TNF-RSC components by BIRC2 and/or BIRC3 and to conjugate linear polyubiquitin to IKBKG and possibly other components contributing to the stability of the complex
  • Together with FAM105B/otulin, the LUBAC complex regulates the canonical Wnt signaling during angiogenesis.

Compare Similar Items

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Img

Thermo Scientific

PIPA599964

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Antigen:
SHARPIN

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SHARPIN

Gene Alias:
0610041B22Rik; AW121341; Conneck1; cpdm; hSIPL1; mSIPL1; protein kinase C-interacting protein RBCC like 1; PSEC0216; RBCKL1; SHANK associated RH domain interactor; SHANK-associated RH domain interacting protein; SHANK-associated RH domain interactor; shank-associated RH domain-interacting protein; shank-interacting protein; shank-interacting protein-like 1; SHARPIN; SIPL1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
106025, 81858, 81859

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q91WA6, Q9EQL9, Q9H0F6

Gene Symbols:
SHARPIN

Immunogen:
A synthesized peptide derived from human SHARPIN(Accession Q9H0F6), corresponding to amino acid residues G66-V116.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA599965

--


Antigen:
STOML2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Stoml2

Gene Alias:
0610038F01Rik; EPB72-like 2; EPB72-like protein 2; HSPC108; MSLP2; Paraprotein target 7; paratarg-7; Slp2; SLP-2; stomatin (Epb7.2)-like 2; stomatin (EPB72)-like 2; stomatin like 2; stomatin-like 2; stomatin-like protein 2, mitochondrial; Stoml2

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
298203, 30968, 66592

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q4FZT0, Q99JB2, Q9UJZ1

Gene Symbols:
Stoml2

Immunogen:
A synthesized peptide derived from human STOML2(Accession Q9UJZ1), corresponding to amino acid residues E176-I226.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA599967

--


Antigen:
VPRBP

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DCAF1

Gene Alias:
AI447437; B930007L02Rik; DCAF1; DDB1 and CUL4 associated factor 1; DDB1- and CUL4-associated factor 1; HIV-1 Vpr binding protein; HIV-1 Vpr-binding protein; KIAA0800; LOW QUALITY PROTEIN: DDB1- and CUL4-associated factor 1; MGC102804; mKIAA0800; Protein VPRBP; protein VPRBP; DDB1- and CUL4-associated factor 1; RGD1305176; RIP; Serine/threonine-protein kinase VPRBP; Vpr (HIV-1) binding protein; Vpr-binding protein; VprBP; vpr-interacting protein

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
315987, 321006, 9730

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q80TR8, Q9Y4B6

Gene Symbols:
DCAF1

Immunogen:
A synthesized peptide derived from human DCAF1(Accession Q9Y4B6), corresponding to amino acid residues D30-K80.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA599970

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Antigen:
SMCR7L

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MIEF1

Gene Alias:
A230016E22; AI452372; dJ1104E15.3; HSU79252; MID51; Mief1; mitochondrial dynamic protein MID51; mitochondrial dynamic protein of 51 kDa; mitochondrial dynamic protein of 51 kDa homolog; mitochondrial dynamics protein MID51; Mitochondrial dynamics protein of 51 kDa; mitochondrial dynamics protein of 51 kDa homolog; Mitochondrial elongation factor 1; Smcr7l; SMCR7-like protein; smith-Magenis syndrome chromosomal region candidate gene 7 protein-like; Smith-Magenis syndrome chromosome region, candidate 7-like

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
239555, 315141, 54471

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q5XIS8, Q8BGV8, Q9NQG6

Gene Symbols:
MIEF1

Immunogen:
A synthesized peptide derived from human MIEF1(Accession Q9NQG6), corresponding to amino acid residues V162-Q212.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG