PITAB1002

Cyclophilin B Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PITAB1002-Each-of-1 In Stock ₹ 40,555.44

PITAB1002 - Each of 1

₹ 40,555.44

In Stock

Quantity

1

Base Price: ₹ 40,555.44

GST (18%): ₹ 7,299.979

Total Price: ₹ 47,855.419

Antigen

Cyclophilin B

Classification

Polyclonal

Conjugate

Unconjugated

Gene

PPIB

Gene Alias

AA408962; AA553318; AI844835; Cphn2; Cphn-2; cyclophilin B; cyclophilin-like protein; Cyp B; CyP-20b; CYPB; CYP-S1; EC 5.2.1.8; epididymis secretory protein Li 39; HEL-S-39; OI9; Peptidyl-prolyl cis-trans isomerase B; peptidylprolyl isomerase B; peptidylprolyl isomerase B (cyclophilin B); PPIase; PPIase B; Ppib; Rotamase; Rotamase B; S-cyclophilin; S-cyclophylin; SCYLP

Host Species

Rabbit

Purification Method

purified

Regulatory Status

RUO

Gene ID (Entrez)

19035, 5479

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1 mg/mL

Formulation

BBS with no preservative; pH 8.4

Gene Accession No.

P23284, P24369

Gene Symbols

PPIB

Immunogen

KLH conjugated peptide representing human cyclophilin B.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

Description

  • TAB1002 detects Cyclophilin B in samples TAB1002 has been successfully been used in Western Blot applications The TAB1002 immunogen is a KLH conjugated peptide corresponding to human cyclophilin B
  • Immunophilins are a family of soluble cytosolic receptors capable of binding to one of two major immunosuppressant agents - cyclosporin A (CsA) or FK506
  • Proteins which bind FK506 are termed FK506 Binding Proteins (FKBP's) and those which bind cyclosporin A are called cyclophilins (CyP)
  • Both CyP:CsA and FKBP:FK506 complexes have been shown to inhibit calcineurin, a calcium and calmodulin dependent protein phosphatase which has been implicated as an important signaling enzyme in T-cell activation
  • Thus, providing a possible mechanism of immunosuppression by CsA and FK506
  • Immunophilins function as peptidyl prolyl cis-trans-isomerases (PPIase) whose activity is inhibited by their respective immunosuppressant compounds
  • As PPIase's, immunophilins accelerate folding of some proteins both in vivo and in vitro by catalyzing slow steps in the initial folding and rearrangement of proline containing proteins.

Compare Similar Items

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Img

Thermo Scientific

PITAB1002

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Antigen:
Cyclophilin B

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PPIB

Gene Alias:
AA408962; AA553318; AI844835; Cphn2; Cphn-2; cyclophilin B; cyclophilin-like protein; Cyp B; CyP-20b; CYPB; CYP-S1; EC 5.2.1.8; epididymis secretory protein Li 39; HEL-S-39; OI9; Peptidyl-prolyl cis-trans isomerase B; peptidylprolyl isomerase B; peptidylprolyl isomerase B (cyclophilin B); PPIase; PPIase B; Ppib; Rotamase; Rotamase B; S-cyclophilin; S-cyclophylin; SCYLP

Host Species:
Rabbit

Purification Method:
purified

Regulatory Status:
RUO

Gene ID (Entrez):
19035, 5479

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
BBS with no preservative; pH 8.4

Gene Accession No.:
P23284, P24369

Gene Symbols:
PPIB

Immunogen:
KLH conjugated peptide representing human cyclophilin B.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PITCR1055

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Antigen:
TCR delta

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
TRD

Gene Alias:
CD3 antigen; CD3d antigen; OKT3

Host Species:
Mouse

Purification Method:
purified

Regulatory Status:
RUO

Gene ID (Entrez):
6964

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation, T-Cell Activation

Concentration:
0.15 mg/mL

Formulation:
PBS with 0.5% BSA and 0.1% sodium azide

Gene Accession No.:
0

Gene Symbols:
TRD

Immunogen:
Human TCR Vdelta1-Jdelta1

Quantity:
200 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

Thermo Scientific

PITCR1642

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Antigen:
TCR V beta 5a

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
TRB

Gene Alias:
T cell receptor beta chain; T cell receptor beta locus; TCRB; TCRbeta; Tib; TRB; TRB@

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
6957

Content And Storage:
-20°C

Form:
Liquid

Applications:
Flow Cytometry, Immunohistochemistry (Frozen), T-Cell Activation

Concentration:
0.15 mg/mL

Formulation:
PBS with 0.5% BSA and 0.1% sodium azide

Gene Accession No.:
P04435

Gene Symbols:
TRB

Immunogen:
Human TCR V beta 5(a)

Quantity:
200 μg

Primary or Secondary:
Primary

Target Species:
Human, Non-human Primate

Product Type:
Antibody

Isotype:
IgG1

Img

Thermo Scientific

PITCR1645

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Antigen:
TCR V beta 5b

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
TRB

Gene Alias:
T cell receptor beta locus; TCRB; TRB; TRB@

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
6957

Content And Storage:
-20°C

Form:
Liquid

Applications:
Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation, T-Cell Activation, Western Blot

Concentration:
0.15 mg/mL

Formulation:
PBS with 0.5% BSA and 0.1% sodium azide

Gene Accession No.:
0

Gene Symbols:
TRB

Immunogen:
Human TCR Vb5.3

Quantity:
200 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1