PITCR1642

TCR V beta 5a Monoclonal Antibody (1C1), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PITCR1642-Each-of-1 In Stock ₹ 40,341.54

PITCR1642 - Each of 1

₹ 40,341.54

In Stock

Quantity

1

Base Price: ₹ 40,341.54

GST (18%): ₹ 7,261.477

Total Price: ₹ 47,603.017

Antigen

TCR V beta 5a

Classification

Monoclonal

Concentration

0.15 mg/mL

Formulation

PBS with 0.5% BSA and 0.1% sodium azide

Gene Accession No.

P04435

Gene Symbols

TRB

Immunogen

Human TCR V beta 5(a)

Quantity

200 μg

Primary or Secondary

Primary

Target Species

Human, Non-human Primate

Product Type

Antibody

Isotype

IgG1

Applications

Flow Cytometry, Immunohistochemistry (Frozen), T-Cell Activation

Clone

1C1

Conjugate

Unconjugated

Gene

TRB

Gene Alias

T cell receptor beta chain; T cell receptor beta locus; TCRB; TCRbeta; Tib; TRB; TRB@

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

6957

Content And Storage

-20°C

Form

Liquid

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Description

  • TCR1642 targets TCR V beta 5a in FACS, IHC(F), and TCA applications and shows reactivity with Human, and Non-human primate samples
  • The TCR1642 immunogen is human TCR V beta 5(a)
  • The ability of T cell receptors (TCR) to discriminate foreign from self-peptides presented by major histocompatibility complex (MHC) class II molecules is essential for an effective adaptive immune response
  • TCR recognition of self-peptides has been linked to autoimmune disease
  • Mutant self-peptides have been associated with tumors
  • Engagement of TCRs by a family of bacterial toxins know as superantigens has been responsible for toxic shock syndrome
  • Autoantibodies to V beta segments of T cell receptors have been isolated from patients with rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE)
  • The autoantibodies block TH1-mediated inflammatory autodestructive reactions and are believed to be a method by which the immune system compensates for disease (ref5)
  • T Cell and TCR Diversity Most human T cells express the TCR alpha-beta and either CD4 or CD8 molecule (single positive, SP)
  • A small number of T cells lack both CD4 and CD8 (double negative, DN)
  • Increased percentages of alpha-beta DN T cells have been identified in some autoimmune and immunodeficiency disorders
  • Gamma-delta T cells are primarily found within the epithelium
  • They show less TCR diversity and recognize antigens differently than alpha-beta T cells
  • Subsets of gamma-delta T cells have shown antitumor and immunoregulatory activity.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PITCR1642

--


Antigen:
TCR V beta 5a

Classification:
Monoclonal

Concentration:
0.15 mg/mL

Formulation:
PBS with 0.5% BSA and 0.1% sodium azide

Gene Accession No.:
P04435

Gene Symbols:
TRB

Immunogen:
Human TCR V beta 5(a)

Quantity:
200 μg

Primary or Secondary:
Primary

Target Species:
Human, Non-human Primate

Product Type:
Antibody

Isotype:
IgG1

Applications:
Flow Cytometry, Immunohistochemistry (Frozen), T-Cell Activation

Clone:
1C1

Conjugate:
Unconjugated

Gene:
TRB

Gene Alias:
T cell receptor beta chain; T cell receptor beta locus; TCRB; TCRbeta; Tib; TRB; TRB@

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
6957

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PITCR1645

--


Antigen:
TCR V beta 5b

Classification:
Monoclonal

Concentration:
0.15 mg/mL

Formulation:
PBS with 0.5% BSA and 0.1% sodium azide

Gene Accession No.:
0

Gene Symbols:
TRB

Immunogen:
Human TCR Vb5.3

Quantity:
200 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation, T-Cell Activation, Western Blot

Clone:
W112

Conjugate:
Unconjugated

Gene:
TRB

Gene Alias:
T cell receptor beta locus; TCRB; TRB; TRB@

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
6957

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PITCR1648

--


Antigen:
TCR V beta 8a

Classification:
Monoclonal

Concentration:
0.15 mg/mL

Formulation:
PBS with 0.5% BSA and 0.1% sodium azide

Gene Accession No.:
0

Gene Symbols:
TRB

Immunogen:
Human TCR V beta 8

Quantity:
200 μg

Primary or Secondary:
Primary

Target Species:
Human, Non-human Primate

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Immunoprecipitation, T-Cell Activation, Western Blot

Clone:
I6G8

Conjugate:
Unconjugated

Gene:
TRB

Gene Alias:
T cell receptor beta locus; TCRB; TRB; TRB@

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
6957

Content And Storage:
-20°C

Form:
Liquid

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PITCR1654

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Antigen:
TCR V beta 12

Classification:
Monoclonal

Concentration:
0.15 mg/mL

Formulation:
PBS with 0.5% BSA and 0.1% sodium azide

Gene Accession No.:
P04435

Gene Symbols:
TRB

Immunogen:
Human TCR V beta 12

Quantity:
200 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation, T-Cell Activation

Clone:
S511

Conjugate:
Unconjugated

Gene:
TRB

Gene Alias:
T cell receptor beta chain; T cell receptor beta locus; TCRB; TCRbeta; Tib; TRB; TRB@

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
6957

Content And Storage:
-20°C

Form:
Liquid