PITCR1648
TCR V beta 8a Monoclonal Antibody (I6G8), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PITCR1648-Each-of-1 | In Stock | ₹ 46,680.50 |
PITCR1648 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,680.50
GST (18%): ₹ 8,402.49
Total Price: ₹ 55,082.99
Antigen
TCR V beta 8a
Classification
Monoclonal
Concentration
0.15 mg/mL
Formulation
PBS with 0.5% BSA and 0.1% sodium azide
Gene Accession No.
0
Gene Symbols
TRB
Immunogen
Human TCR V beta 8
Quantity
200 μg
Primary or Secondary
Primary
Target Species
Human, Non-human Primate
Product Type
Antibody
Isotype
IgG2b
Applications
Immunocytochemistry, Immunohistochemistry (Frozen), Immunoprecipitation, T-Cell Activation, Western Blot
Clone
I6G8
Conjugate
Unconjugated
Gene
TRB
Gene Alias
T cell receptor beta locus; TCRB; TRB; TRB@
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
6957
Content And Storage
-20°C
Form
Liquid
Related Products
Description
- TCR1648 targets TCR V beta 8a in FACS, IHC(F), IP, TCA, and WB applications and shows reactivity with Human, and Non-human primate samples
- The TCR1648 immunogen is human TCR V beta 8
- The ability of T cell receptors (TCR) to discriminate foreign from self-peptides presented by major histocompatibility complex (MHC) class II molecules is essential for an effective adaptive immune response
- TCR recognition of self-peptides has been linked to autoimmune disease
- Mutant self-peptides have been associated with tumors
- Engagement of TCRs by a family of bacterial toxins know as superantigens has been responsible for toxic shock syndrome
- Autoantibodies to V beta segments of T cell receptors have been isolated from patients with rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE)
- The autoantibodies block TH1-mediated inflammatory autodestructive reactions and are believed to be a method by which the immune system compensates for disease (ref5)
- T Cell and TCR Diversity Most human T cells express the TCR alpha-beta and either CD4 or CD8 molecule (single positive, SP)
- A small number of T cells lack both CD4 and CD8 (double negative, DN)
- Increased percentages of alpha-beta DN T cells have been identified in some autoimmune and immunodeficiency disorders
- Gamma-delta T cells are primarily found within the epithelium
- They show less TCR diversity and recognize antigens differently than alpha-beta T cells
- Subsets of gamma-delta T cells have shown antitumor and immunoregulatory activity.
Compare Similar Items
Show Difference
Antigen: TCR V beta 8a
Classification: Monoclonal
Concentration: 0.15 mg/mL
Formulation: PBS with 0.5% BSA and 0.1% sodium azide
Gene Accession No.: 0
Gene Symbols: TRB
Immunogen: Human TCR V beta 8
Quantity: 200 μg
Primary or Secondary: Primary
Target Species: Human, Non-human Primate
Product Type: Antibody
Isotype: IgG2b
Applications: Immunocytochemistry, Immunohistochemistry (Frozen), Immunoprecipitation, T-Cell Activation, Western Blot
Clone: I6G8
Conjugate: Unconjugated
Gene: TRB
Gene Alias: T cell receptor beta locus; TCRB; TRB; TRB@
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 6957
Content And Storage: -20°C
Form: Liquid
Antigen:
TCR V beta 8a
Classification:
Monoclonal
Concentration:
0.15 mg/mL
Formulation:
PBS with 0.5% BSA and 0.1% sodium azide
Gene Accession No.:
0
Gene Symbols:
TRB
Immunogen:
Human TCR V beta 8
Quantity:
200 μg
Primary or Secondary:
Primary
Target Species:
Human, Non-human Primate
Product Type:
Antibody
Isotype:
IgG2b
Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Immunoprecipitation, T-Cell Activation, Western Blot
Clone:
I6G8
Conjugate:
Unconjugated
Gene:
TRB
Gene Alias:
T cell receptor beta locus; TCRB; TRB; TRB@
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
6957
Content And Storage:
-20°C
Form:
Liquid
Antigen: TCR V beta 12
Classification: Monoclonal
Concentration: 0.15 mg/mL
Formulation: PBS with 0.5% BSA and 0.1% sodium azide
Gene Accession No.: P04435
Gene Symbols: TRB
Immunogen: Human TCR V beta 12
Quantity: 200 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2b
Applications: Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation, T-Cell Activation
Clone: S511
Conjugate: Unconjugated
Gene: TRB
Gene Alias: T cell receptor beta chain; T cell receptor beta locus; TCRB; TCRbeta; Tib; TRB; TRB@
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 6957
Content And Storage: -20°C
Form: Liquid
Antigen:
TCR V beta 12
Classification:
Monoclonal
Concentration:
0.15 mg/mL
Formulation:
PBS with 0.5% BSA and 0.1% sodium azide
Gene Accession No.:
P04435
Gene Symbols:
TRB
Immunogen:
Human TCR V beta 12
Quantity:
200 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2b
Applications:
Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation, T-Cell Activation
Clone:
S511
Conjugate:
Unconjugated
Gene:
TRB
Gene Alias:
T cell receptor beta chain; T cell receptor beta locus; TCRB; TCRbeta; Tib; TRB; TRB@
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
6957
Content And Storage:
-20°C
Form:
Liquid
Antigen: TCR V delta 1
Classification: Monoclonal
Concentration: 0.15 mg/mL
Formulation: PBS with 0.5% BSA and 0.1% sodium azide
Gene Accession No.: 0
Gene Symbols: TRD
Immunogen: Human TCR V delta 1
Quantity: 200 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: Flow Cytometry, Immunohistochemistry (Frozen), T-Cell Activation
Clone: TS8.2
Conjugate: Unconjugated
Gene: TRD
Gene Alias: __
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 6964
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
TCR V delta 1
Classification:
Monoclonal
Concentration:
0.15 mg/mL
Formulation:
PBS with 0.5% BSA and 0.1% sodium azide
Gene Accession No.:
0
Gene Symbols:
TRD
Immunogen:
Human TCR V delta 1
Quantity:
200 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Flow Cytometry, Immunohistochemistry (Frozen), T-Cell Activation
Clone:
TS8.2
Conjugate:
Unconjugated
Gene:
TRD
Gene Alias:
__
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
6964
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: TCR V beta 8b
Classification: Monoclonal
Concentration: 0.15 mg/mL
Formulation: PBS with 0.5% BSA and 0.1% sodium azide
Gene Accession No.: 0
Gene Symbols: TRB
Immunogen: Human TCR Vbeta8
Quantity: 200 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2a
Applications: Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation, T-Cell Activation
Clone: MX-6
Conjugate: Unconjugated
Gene: TRB
Gene Alias: T cell receptor beta locus; TCRB; TRB; TRB@
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 6957
Content And Storage: -20°C
Form: Liquid
Antigen:
TCR V beta 8b
Classification:
Monoclonal
Concentration:
0.15 mg/mL
Formulation:
PBS with 0.5% BSA and 0.1% sodium azide
Gene Accession No.:
0
Gene Symbols:
TRB
Immunogen:
Human TCR Vbeta8
Quantity:
200 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2a
Applications:
Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation, T-Cell Activation
Clone:
MX-6
Conjugate:
Unconjugated
Gene:
TRB
Gene Alias:
T cell receptor beta locus; TCRB; TRB; TRB@
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
6957
Content And Storage:
-20°C
Form:
Liquid