RM9101S

Estrogen Receptor (SP1) Rabbit Monoclonal Antibody, Epredia™

Manufacturer: Fischer Scientific

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Antigen

Estrogen Receptor (SP1)

Classification

Monoclonal

Conjugate

Unconjugated

Immunogen

Synthetic peptide derived from C-terminal of human estrogen receptor

Regulatory Status

IVD

Primary or Secondary

Primary

Form

Concentrated

Applications

Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Clone

SP1

Host Species

Rabbit

Quantity

1 mL

Research Discipline

Steroids Hormones and Growth Factors

Target Species

Hamster, Human, Mouse

Isotype

IgG

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Description

  • Description Recognizes a protein of 67 kDa, which is identified as estrogen receptor (ER) alpha
  • The ER gene consists of more than 140kb of genomic DNA divided into 8 exons, and is translated into a protein with six functionally discrete domains, labeled A through F
  • This antibody strongly stains the nucleus of epithelial cells in breast carcinomas
  • The ER is an important regulator of growth and differentiation in the mammary gland
  • Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g
  • tamoxifen) therapy
  • Host Species: Rabbit Clone: SP1 Isotype: IgG Species Reactivity: Human, Mouse and Hamster
  • Others not tested
  • Epitope: C-terminus Immunogen: Synthetic peptide derived from C-terminal of human estrogen receptor Molecular Weight: 67 kDa Positive Control: Breast CA, MCF-7 cells Cellular Localization: Nuclear Recommended for: Immunohistochemistry (Formalin/paraffin) Western Blotting Immunofluorescence (Not verified) Flow Cytometery (Not verified)

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Img

Fischer Scientific

RM9101S

--


Antigen:
Estrogen Receptor (SP1)

Classification:
Monoclonal

Conjugate:
Unconjugated

Immunogen:
Synthetic peptide derived from C-terminal of human estrogen receptor

Regulatory Status:
IVD

Primary or Secondary:
Primary

Form:
Concentrated

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Clone:
SP1

Host Species:
Rabbit

Quantity:
1 mL

Research Discipline:
Steroids Hormones and Growth Factors

Target Species:
Hamster, Human, Mouse

Isotype:
IgG

Img

Fischer Scientific

RM9101S0

--


Antigen:
Estrogen Receptor (SP1)

Classification:
Monoclonal

Conjugate:
Unconjugated

Immunogen:
Synthetic peptide derived from C-terminal of human estrogen receptor

Regulatory Status:
IVD

Primary or Secondary:
Primary

Form:
Concentrated

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Clone:
SP1

Host Species:
Rabbit

Quantity:
100 μL

Research Discipline:
Steroids Hormones and Growth Factors

Target Species:
Hamster, Human, Mouse

Isotype:
IgG

Img

Fischer Scientific

RM9101S1

--


Antigen:
Estrogen Receptor (SP1)

Classification:
Monoclonal

Conjugate:
Unconjugated

Immunogen:
Synthetic peptide derived from C-terminal of human estrogen receptor

Regulatory Status:
IVD

Primary or Secondary:
Primary

Form:
Concentrated

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Clone:
SP1

Host Species:
Rabbit

Quantity:
500 μL

Research Discipline:
Steroids Hormones and Growth Factors

Target Species:
Hamster, Human, Mouse

Isotype:
IgG

Img

Fischer Scientific

RM9102R1

--


Antigen:
Progesterone Receptor (SP2)

Classification:
Monoclonal

Conjugate:
Unconjugated

Immunogen:
Recombinant protein encoding human progesterone receptor 412-526 aa

Regulatory Status:
IVD

Primary or Secondary:
Primary

Form:
Prediluted

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
SP2

Host Species:
Rabbit

Quantity:
1 mL

Research Discipline:
Cancer and Tumor Biology

Target Species:
Human

Isotype:
IgG