RM9101S1

Estrogen Receptor (SP1) Rabbit Monoclonal Antibody, Epredia™

Manufacturer: Fischer Scientific

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Antigen

Estrogen Receptor (SP1)

Classification

Monoclonal

Conjugate

Unconjugated

Immunogen

Synthetic peptide derived from C-terminal of human estrogen receptor

Regulatory Status

IVD

Primary or Secondary

Primary

Form

Concentrated

Applications

Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Clone

SP1

Host Species

Rabbit

Quantity

500 μL

Research Discipline

Steroids Hormones and Growth Factors

Target Species

Hamster, Human, Mouse

Isotype

IgG

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Description

  • Description Recognizes a protein of 67 kDa, which is identified as estrogen receptor (ER) alpha
  • The ER gene consists of more than 140kb of genomic DNA divided into 8 exons, and is translated into a protein with six functionally discrete domains, labeled A through F
  • This antibody strongly stains the nucleus of epithelial cells in breast carcinomas
  • The ER is an important regulator of growth and differentiation in the mammary gland
  • Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g
  • tamoxifen) therapy
  • Host Species: Rabbit Clone: SP1 Isotype: IgG Species Reactivity: Human, Mouse and Hamster
  • Others not tested
  • Epitope: C-terminus Immunogen: Synthetic peptide derived from C-terminal of human estrogen receptor Molecular Weight: 67 kDa Positive Control: Breast CA, MCF-7 cells Cellular Localization: Nuclear Recommended for: Immunohistochemistry (Formalin/paraffin) Western Blotting Immunofluorescence (Not verified) Flow Cytometery (Not verified)

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Img

Fischer Scientific

RM9101S1

--


Antigen:
Estrogen Receptor (SP1)

Classification:
Monoclonal

Conjugate:
Unconjugated

Immunogen:
Synthetic peptide derived from C-terminal of human estrogen receptor

Regulatory Status:
IVD

Primary or Secondary:
Primary

Form:
Concentrated

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Clone:
SP1

Host Species:
Rabbit

Quantity:
500 μL

Research Discipline:
Steroids Hormones and Growth Factors

Target Species:
Hamster, Human, Mouse

Isotype:
IgG

Img

Fischer Scientific

RM9102R1

--


Antigen:
Progesterone Receptor (SP2)

Classification:
Monoclonal

Conjugate:
Unconjugated

Immunogen:
Recombinant protein encoding human progesterone receptor 412-526 aa

Regulatory Status:
IVD

Primary or Secondary:
Primary

Form:
Prediluted

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
SP2

Host Species:
Rabbit

Quantity:
1 mL

Research Discipline:
Cancer and Tumor Biology

Target Species:
Human

Isotype:
IgG

Img

Fischer Scientific

RM9102R7

--


Antigen:
Progesterone Receptor (SP2)

Classification:
Monoclonal

Conjugate:
Unconjugated

Immunogen:
Recombinant protein encoding human progesterone receptor 412-526 aa

Regulatory Status:
IVD

Primary or Secondary:
Primary

Form:
Prediluted

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
SP2

Host Species:
Rabbit

Quantity:
7 mL

Research Discipline:
Cancer and Tumor Biology

Target Species:
Human

Isotype:
IgG

Img

Fischer Scientific

RM9102RQ

--


Antigen:
Progesterone Receptor (SP2)

Classification:
Monoclonal

Conjugate:
Unconjugated

Immunogen:
Recombinant protein encoding human progesterone receptor 412-526 aa

Regulatory Status:
IVD

Primary or Secondary:
Primary

Form:
Ready-to-Use

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
SP2

Host Species:
Rabbit

Quantity:
12 mL

Research Discipline:
Cancer and Tumor Biology

Target Species:
__

Isotype:
__