RM9133R7

Epredia™ Lab Vision™ Pax-5 Rabbit Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

PAX-5

Classification

Monoclonal

Conjugate

Unconjugated

Immunogen

Synthetic peptide derived from the C-terminus of human Pax-5 protein

Regulatory Status

IVD

Primary or Secondary

Primary

Form

Prediluted

Applications

Immunohistochemistry (Paraffin)

Clone

SP34

Host Species

Rabbit

Quantity

7 mL

Research Discipline

Cancer and Tumor Biology

Target Species

Human

Isotype

IgG

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Description

  • Description PAX-5 is a B-cell-specific activator protein (BSAP)
  • In the early stages of B cell developmemt, PAX-5 influences the expression of several B-cell-specific genes, such as CD19 and CD20
  • PAX-5 is expressed primarily in pro-, pre-, and mature B cells, but not in plasma cells
  • PAX-5 is expressed in most B-cell malignancies (pre-B and mature B cell lymphomas/leukemias)
  • Over 90% of cases are positive for PAX-5 in Hodgkin's lymphoma, lymphoplasmacytic lymphoma, Merkel cell and small cell carcinoma
  • T-cell lymphomas, myeloma/plasmacytoma and carcinoid tumors are negative for PAX-5
  • Host Species: Rabbit Clone: SP34 Isotype: IgG Species Reactivity: Human
  • Others not tested
  • Immunogen: Synthetic peptide derived from the C-terminus of human PAX-5 protein Molecular Weight: 50kDa Positive Control: Tonsil Cellular Localization: Nuclear Recommended for: Immunohistochemistry (Formalin/paraffin)

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Img

Fischer Scientific

RM9133R7

--


Antigen:
PAX-5

Classification:
Monoclonal

Conjugate:
Unconjugated

Immunogen:
Synthetic peptide derived from the C-terminus of human Pax-5 protein

Regulatory Status:
IVD

Primary or Secondary:
Primary

Form:
Prediluted

Applications:
Immunohistochemistry (Paraffin)

Clone:
SP34

Host Species:
Rabbit

Quantity:
7 mL

Research Discipline:
Cancer and Tumor Biology

Target Species:
Human

Isotype:
IgG

Img

Fischer Scientific

RM9133RQ

--


Antigen:
PAX-5

Classification:
Monoclonal

Conjugate:
Unconjugated

Immunogen:
Synthetic peptide derived from the C-terminus of human Pax-5 protein

Regulatory Status:
IVD

Primary or Secondary:
Primary

Form:
Ready-to-Use

Applications:
Immunohistochemistry (Paraffin)

Clone:
SP34

Host Species:
Rabbit

Quantity:
12 mL

Research Discipline:
Cancer and Tumor Biology

Target Species:
__

Isotype:
__

Img

Fischer Scientific

RM9133S

--


Antigen:
PAX-5

Classification:
Monoclonal

Conjugate:
Unconjugated

Immunogen:
Synthetic peptide derived from the C-terminus of human Pax-5 protein

Regulatory Status:
IVD

Primary or Secondary:
Primary

Form:
Concentrated

Applications:
Immunohistochemistry (Paraffin)

Clone:
SP34

Host Species:
Rabbit

Quantity:
1 mL

Research Discipline:
Cancer and Tumor Biology

Target Species:
Human

Isotype:
IgG

Img

Fischer Scientific

RM9133S0

--


Antigen:
PAX-5

Classification:
Monoclonal

Conjugate:
Unconjugated

Immunogen:
Synthetic peptide derived from the C-terminus of human Pax-5 protein

Regulatory Status:
IVD

Primary or Secondary:
Primary

Form:
Concentrated

Applications:
Immunohistochemistry (Paraffin)

Clone:
SP34

Host Species:
Rabbit

Quantity:
100 μL

Research Discipline:
Cancer and Tumor Biology

Target Species:
Human

Isotype:
IgG