ST107050UG

MilliporeSigma™ anti-Tiam1, Polyclonal

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 ST107050UG-Each-of-1 In Stock ₹ 25,021.17

ST107050UG - Each of 1

₹ 25,021.17

In Stock

Quantity

1

Base Price: ₹ 25,021.17

GST (18%): ₹ 4,503.811

Total Price: ₹ 29,524.981

Antigen

Tiam1

Classification

Polyclonal

Formulation

In Tris-Citrate/phosphate, pH 7.0-8.0.

Immunogen

a synthetic peptide corresponding to amino acids from the C-terminal domain of human Tiam1

Regulatory Status

RUO

Test Specificity

Recognizes the ∽200kDa Tiam1 protein in Jurkat and NIH3T3 cells.

Content And Storage

2°C to 8°C

Isotype

IgG

Applications

Immunoblot

Conjugate

Unconjugated

Host Species

Rabbit

Quantity

50 μg

Primary or Secondary

Primary

Target Species

Human, Mouse

Form

Purified

Related Products

Img

MilliporeSigma™

ST104250UG

--

Img

MilliporeSigma™

PC116100UG

--

Img

MilliporeSigma™

OP38100UG

--

Img

MilliporeSigma™

PC05L100UG

--

Img

MilliporeSigma™

ST109950UL

--

Img

MilliporeSigma™

PC138100UL

--

Img

MilliporeSigma™

ST1684100UG

--

Img

MilliporeSigma™

ST1598100UG

--

Description

  • Specifically detects Tiam1 Clone: in Human, Mouse samples, and it is validated for Immuno Blotting Tiam1 (T-cell lymphoma invasion and metastasis 1) was originally identified by its ability to induce invasion by T-lymphoma cells when amplified
  • Tiam1 is a specific guanine nucleotide exchange factor (GEF) for the GTPase, Rac
  • By activating Rac1, Tiam1 regulates many cellular functions including actin cytoskeleton dynamics, cell proliferation, and cell survival
  • Tiam1 activity is regulated by its translocation to the membrane and the subsequent binding of its PH domain to phosphatidylinositol-3,4,5-triphosphate
  • Tiam1 is cleaved in a caspase-dependent manner in apoptotic cells, rendering it inactive as a result of an inability to translocate to the plasma membrane.

Compare Similar Items

Show Difference

Img

MilliporeSigma™

ST107050UG

--


Antigen:
Tiam1

Classification:
Polyclonal

Formulation:
In Tris-Citrate/phosphate, pH 7.0-8.0.

Immunogen:
a synthetic peptide corresponding to amino acids from the C-terminal domain of human Tiam1

Regulatory Status:
RUO

Test Specificity:
Recognizes the ∽200kDa Tiam1 protein in Jurkat and NIH3T3 cells.

Content And Storage:
2°C to 8°C

Isotype:
IgG

Applications:
Immunoblot

Conjugate:
Unconjugated

Host Species:
Rabbit

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Form:
Purified

Img

MilliporeSigma™

ST10881SET

--


Antigen:
Akt, PH Domain

Classification:
Monoclonal

Formulation:
100μg antibody in 150mM NaCl, 100mM Tris-glycine, 30% glycerol, pH 7.4 and 100μg control lysate.

Immunogen:
a recombinant protein consisting of amino acids 1-149 of human Akt 1 fused to GST

Regulatory Status:
RUO

Test Specificity:
Recognizes the ∽60kDa Akt protein in A431 cells. Useful for the concentration of Akt in samples by immunoprecipitation prior to use in the K-LISA™ Akt Activity Kit. Antibody Target Gene Symbol: AKT1 Target Synonym: AKT, MGC99656, PKB, PKB-ALPHA, PKB/AKT, PRKBA, Protein kinase B, RAC, RAC-ALPHA, Thymoma viral proto-oncogene 1 Entrez Gene Name: v-akt murine thymoma viral oncogene homolog 1

Content And Storage:
−20°C

Isotype:
IgG

Applications:
Flow Cytometry, Immunoblot, Immunoblot, Immunoprecipitation

Conjugate:
Unconjugated

Host Species:
Mouse

Quantity:
1 Set

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Purified

Img

MilliporeSigma™

ST109850UL

--


Antigen:
PAN TORC (1-42)

Classification:
Polyclonal

Formulation:
Undiluted serum.

Immunogen:
a recombinant protein consisting of amino acids 1-42 of human TORC1 fused to GST

Regulatory Status:
RUO

Test Specificity:
Recognizes the ∽79kDa TORC1, TORC2, and TORC3 proteins in 293T cells over-expressing TORC1, TORC2, or TORC3. Recognizes endogenous TORC1 and TORC2.

Content And Storage:
2°C to 8°C

Isotype:
IgG

Applications:
Immunoprecipitation

Conjugate:
Unconjugated

Host Species:
Rabbit

Quantity:
50 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Undiluted

Img

MilliporeSigma™

ST109950UL

--


Antigen:
TORC2 (454-607)

Classification:
Polyclonal

Formulation:
Undiluted serum.

Immunogen:
a recombinant protein consisting of amino acids 454-607 of mouse TORC2 fused to GST

Regulatory Status:
RUO

Test Specificity:
Recognizes the ∽79-85kDa TORC2 protein in primary hepatocytes, HepG2, NIH3T3, Min6, and FAO cells.

Content And Storage:
2°C to 8°C

Isotype:
IgG

Applications:
Immunoprecipitation

Conjugate:
Unconjugated

Host Species:
Rabbit

Quantity:
50 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
__