7082192
Tocris Bioscience™ AM 6545
High affinity and selective CB1 antagonist
Manufacturer: Fischer Scientific
CAS Number: 1245626-05-4
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Chemical Name or Material
AM 6545
Synonym
5-[4-(4-Cyano-1-butyn-1-yl)phenyl]-1-(2,4-dichlorophenyl)-N-(1,1-dioxido-4-thiomorpholinyl)-4-methyl-1H-pyrazole-3-carboxamide
Molecular Formula
C26H23Cl2N5O3S
Physical Form
Solid
Purity
>98%
CAS
1245626-05-4
Solubility
Soluble to 20mM in DMSO
Formula Weight
556.46
Product Type
Bioactive Small Molecule
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ AM 6545 | Fischer Scientific | ₹ 29,774.88 | |
| | Tocris Bioscience™ AM 6545 | Fischer Scientific | ₹ 1,24,489.80 | |
 | AM6545 | ChemScene | ₹ 8,812.68 | |
 | 1245626-05-4 | AM6545 | A2B Chem | ₹ 3,422.40 - ₹ 98,565.12 |
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Description
- High affinity and selective CB1 antagonist (Ki = 3.3 nM)
- Exhibits >100-fold selectivity for CB1 over CB2 receptors
- Improves glucose homeostasis, reverses hepatic steatosis and reduces body weight in diet-induced obese mice
- Orally available and non-brain penetrant.
SAFETY INFORMATION
- Recommended Storage : Store at 4°C
Compare Similar Items
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Chemical Name or Material: AM 6545
Synonym: 5-[4-(4-Cyano-1-butyn-1-yl)phenyl]-1-(2,4-dichlorophenyl)-N-(1,1-dioxido-4-thiomorpholinyl)-4-methyl-1H-pyrazole-3-carboxamide
Molecular Formula: C26H23Cl2N5O3S
Physical Form: Solid
Purity: >98%
CAS: 1245626-05-4
Solubility: Soluble to 20mM in DMSO
Formula Weight: 556.46
Product Type: Bioactive Small Molecule
Chemical Name or Material:
AM 6545
Synonym:
5-[4-(4-Cyano-1-butyn-1-yl)phenyl]-1-(2,4-dichlorophenyl)-N-(1,1-dioxido-4-thiomorpholinyl)-4-methyl-1H-pyrazole-3-carboxamide
Molecular Formula:
C26H23Cl2N5O3S
Physical Form:
Solid
Purity:
>98%
CAS:
1245626-05-4
Solubility:
Soluble to 20mM in DMSO
Formula Weight:
556.46
Product Type:
Bioactive Small Molecule
Chemical Name or Material: QAQ dichloride
Synonym: 2,2'-[1,2-Diazenediylbis(4,1-phenyleneimino)bis[N,N,N-triethyl-2-oxo-ethanaminium] dichloride
Molecular Formula: C28H44Cl2N6O2
Physical Form: Solid
Purity: >98%
CAS: __
Solubility: Soluble to 50mM in water
Formula Weight: 567.59
Product Type: Bioactive Small Molecule
Chemical Name or Material:
QAQ dichloride
Synonym:
2,2'-[1,2-Diazenediylbis(4,1-phenyleneimino)bis[N,N,N-triethyl-2-oxo-ethanaminium] dichloride
Molecular Formula:
C28H44Cl2N6O2
Physical Form:
Solid
Purity:
>98%
CAS:
__
Solubility:
Soluble to 50mM in water
Formula Weight:
567.59
Product Type:
Bioactive Small Molecule
Chemical Name or Material: KRIBB11
Synonym: N2-1H-Indazol-5-yl-N6-methyl-3-nitro-2,6-pyridinediamine
Molecular Formula: C13H12N6O2
Physical Form: Solid
Purity: >99%
CAS: 342639-96-7
Solubility: Soluble to 100mM in DMSO
Formula Weight: 284.27
Product Type: Bioactive Small Molecule
Chemical Name or Material:
KRIBB11
Synonym:
N2-1H-Indazol-5-yl-N6-methyl-3-nitro-2,6-pyridinediamine
Molecular Formula:
C13H12N6O2
Physical Form:
Solid
Purity:
>99%
CAS:
342639-96-7
Solubility:
Soluble to 100mM in DMSO
Formula Weight:
284.27
Product Type:
Bioactive Small Molecule
Chemical Name or Material: C 87
Synonym: 3-Phenyl-1-(4-phenyl-2-thiazolyl)-1H-pyrazole-4,5-dione 4-[2-(4-chloro-3-nitrophenyl)hydrazone]
Molecular Formula: C24H15ClN6O3S
Physical Form: Solid
Purity: >98%
CAS: 332420-90-3
Solubility: Soluble to 20mM in DMSO
Formula Weight: 502.93
Product Type: Bioactive Small Molecule
Chemical Name or Material:
C 87
Synonym:
3-Phenyl-1-(4-phenyl-2-thiazolyl)-1H-pyrazole-4,5-dione 4-[2-(4-chloro-3-nitrophenyl)hydrazone]
Molecular Formula:
C24H15ClN6O3S
Physical Form:
Solid
Purity:
>98%
CAS:
332420-90-3
Solubility:
Soluble to 20mM in DMSO
Formula Weight:
502.93
Product Type:
Bioactive Small Molecule