7082194

Tocris Bioscience™ QAQ Dichloride

Photoswitchable Nav, Kv and Cav channel blocker

Manufacturer: Fischer Scientific

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Chemical Name or Material

QAQ dichloride

Solubility

Soluble to 50mM in water

Molecular Formula

C28H44Cl2N6O2

Physical Form

Solid

Purity

>98%

Synonym

2,2'-[1,2-Diazenediylbis(4,1-phenyleneimino)bis[N,N,N-triethyl-2-oxo-ethanaminium] dichloride

Target

Non-selective Cav Blockers

Formula Weight

567.59

Product Type

Bioactive Small Molecule

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Description

  • Photoswitchable Nav, Cav and Kv channel blocker
  • Blocks channels in the trans conformation
  • Switches conformation from cis to trans at 500 nm and trans to cis at 380 nm
  • Normally membrane impermeant, but enters nociceptive neurons via ion channels activated by noxious stimuli, particularly TRPV1
  • Exhibits optically reversible local anesthesia in rats.

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C

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Chemical Name or Material:
QAQ dichloride

Solubility:
Soluble to 50mM in water

Molecular Formula:
C28H44Cl2N6O2

Physical Form:
Solid

Purity:
>98%

Synonym:
2,2'-[1,2-Diazenediylbis(4,1-phenyleneimino)bis[N,N,N-triethyl-2-oxo-ethanaminium] dichloride

Target:
Non-selective Cav Blockers

Formula Weight:
567.59

Product Type:
Bioactive Small Molecule

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C13H12N6O2

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Solid

Purity:
>99%

Synonym:
N2-1H-Indazol-5-yl-N6-methyl-3-nitro-2,6-pyridinediamine

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284.27

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Bioactive Small Molecule

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Molecular Formula:
C24H15ClN6O3S

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C16H20N2O2S2

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5-Methyl-N-[2-(1-piperidinyl)phenyl]-2-thiophenesulfonamide

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__

Formula Weight:
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Product Type:
Bioactive Small Molecule