D3669

3,3′-Dithiodipropionic acid di(N-hydroxysuccinimide ester)

powder

Manufacturer: Sigma Aldrich

CAS Number: 57757-57-0

Synonym(S): DTSP, Di(N-succinimidyl) 3,3′-dithiodipropionate, Dithiobis(succinimidyl propionate), Lomant’s reagent

Select a Size

Pack Size SKU Availability Price
500 MG D3669-500-MG In Stock ₹ 21,585.05
1 G D3669-1-G In Stock ₹ 39,467.95

D3669 - 500 MG

₹ 21,585.05

In Stock

Quantity

1

Base Price: ₹ 21,585.05

GST (18%): ₹ 3,885.309

Total Price: ₹ 25,470.359

form

powder

Quality Level

200

reaction suitability

reagent type: cross-linking reagent

solubility

chloroform: 50 mg/mLDMF: solubleacetone: soluble

storage temp.

−20°C

SMILES string

O=C(CCSSCCC(=O)ON1C(=O)CCC1=O)ON2C(=O)CCC2=O

InChI

1S/C14H16N2O8S2/c17-9-1-2-10(18)15(9)23-13(21)5-7-25-26-8-6-14(22)24-16-11(19)3-4-12(16)20/h1-8H2

InChI key

FXYPGCIGRDZWNR-UHFFFAOYSA-N

Other Options

Image Product Name Manufacturer Price Range
NC0035835
Proteochem Inc DSP Crosslinker, 57757-57-0, MFCD00042045, 100 mg
Proteochem Inc ₹ 9,249.04
50-171-6721
eMolecules​ Dithio-bis-succinimidyl propionate (Lomant?s Reagent) | 57757-57-0 | MFCD00042045 | 250mg
eMolecules​ ₹ 18,261.93
CS-0068460
DSP Crosslinker
ChemScene ₹ 427.80 - ₹ 33,282.84

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Description

  • General description: 3,3′-Dithiodipropionic acid di(N-hydroxysuccinimide ester) (DSP) is a homobifunctional cross-linking reagent containing a cleavable disulfide linkage. It is typically coupled to molecules containing primary amines by amide bonds buffered at pH 7.5 (6.5-8.5).[1]
  • Application: 3,3′-Dithiodipropionic acid di(N-hydroxysuccinimide ester) (DSP) has been used as a protein cross-linker.[2][3]
  • Features and Benefits: The disulfide linkage is cleavable by mild reduction.
  • Caution: Avoid use of reducing agents during coupling reactions.

SAFETY INFORMATION

Pictograms

GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Precautionary Statements

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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form:
powder

Quality Level:
200

reaction suitability:
reagent type: cross-linking reagent

solubility:
chloroform: 50 mg/mLDMF: solubleacetone: soluble

storage temp.:
−20°C

SMILES string:
O=C(CCSSCCC(=O)ON1C(=O)CCC1=O)ON2C(=O)CCC2=O

InChI:
1S/C14H16N2O8S2/c17-9-1-2-10(18)15(9)23-13(21)5-7-25-26-8-6-14(22)24-16-11(19)3-4-12(16)20/h1-8H2

InChI key:
FXYPGCIGRDZWNR-UHFFFAOYSA-N

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SMILES string:
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InChI:
__

InChI key:
__

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InChI:
1S/C18H32O16/c19-1-5(21)9(23)10(24)6(22)3-31-17-16(30)14(28)12(26)8(34-17)4-32-18-15(29)13(27)11(25)7(2-20)33-18/h1,5-18,20-30H,2-4H2

InChI key:
FZWBNHMXJMCXLU-UHFFFAOYSA-N