760668

Dibenzocyclooctyne-maleimide

for Copper-free Click Chemistry

Manufacturer: Sigma Aldrich

Synonym(S): DBCO-maleimide

Select a Size

Pack Size SKU Availability Price
1 MG 760668-1-MG In Stock ₹ 2,132.53
5 MG 760668-5-MG In Stock ₹ 7,978.03
50 MG 760668-50-MG In Stock ₹ 17,060.20

760668 - 1 MG

₹ 2,132.53

In Stock

Quantity

1

Base Price: ₹ 2,132.53

GST (18%): ₹ 383.855

Total Price: ₹ 2,516.385

Quality Level

100

form

solid

reaction suitability

reaction type: click chemistryreagent type: cross-linking reagent

functional group

maleimide

storage temp.

−20°C

SMILES string

O=C(N1CCC(NCCC(N2CC3=C(C=CC=C3)C#CC4=C2C=CC=C4)=O)=O)C=CC1=O

InChI

1S/C25H21N3O4/c29-22(14-16-27-23(30)11-12-24(27)31)26-15-13-25(32)28-17-20-7-2-1-5-18(20)9-10-19-6-3-4-8-21(19)28/h1-8,11-12H,13-17H2,(H,26,29)

InChI key

NHFQNAGPXIVKND-UHFFFAOYSA-N

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Description

  • Application: Maleimide functionalized cyclooctyne derivative for incorporation of the cyclooctyne moiety into thiol containing compounds or biomolecules. Cyclooctynes are useful in strain-promoted copper-free azide-alkyne cycloaddition reactions. This dibenzocyclooctyne will react with azide functionalized compounds or biomolecules without the need for a Cu(I) catalyst to result in a stable triazole linkage. Applications Include: Protein-peptide conjugatesAntibody-enzyme or antibody-drug conjugatesProtein or peptide-oligonucleotide conjugates Surface modification

SAFETY INFORMATION

Pictograms

GHS09

Signal Word

Warning

Hazard Statements

H400

Precautionary Statements

P273

Hazard Classifications

Aquatic Acute 1

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Compare Similar Items

Show Difference

Img

Sigma Aldrich

760668

for Copper-free Click Chemistry...


Quality Level:
100

form:
solid

reaction suitability:
reaction type: click chemistryreagent type: cross-linking reagent

functional group:
maleimide

storage temp.:
−20°C

SMILES string:
O=C(N1CCC(NCCC(N2CC3=C(C=CC=C3)C#CC4=C2C=CC=C4)=O)=O)C=CC1=O

InChI:
1S/C25H21N3O4/c29-22(14-16-27-23(30)11-12-24(27)31)26-15-13-25(32)28-17-20-7-2-1-5-18(20)9-10-19-6-3-4-8-21(19)28/h1-8,11-12H,13-17H2,(H,26,29)

InChI key:
NHFQNAGPXIVKND-UHFFFAOYSA-N

Img

Sigma Aldrich

760676

for Copper-free Click Chemistry...


Quality Level:
__

form:
solid

reaction suitability:
reaction type: click chemistryreagent type: cross-linking reagent

functional group:
maleimide

storage temp.:
−20°C

SMILES string:
O=C(CCNC(CCOCCOCCOCCOCCNC(CCN1C(C=CC1=O)=O)=O)=O)N2CC3=C(C=CC=C3)C#CC4=C2C=CC=C4

InChI:
1S/C36H42N4O9/c41-32(14-18-39-34(43)11-12-35(39)44)38-17-20-47-22-24-49-26-25-48-23-21-46-19-15-33(42)37-16-13-36(45)40-27-30-7-2-1-5-28(30)9-10-29-6-3-4-8-31(29)40/h1-8,11-12H,13-27H2,(H,37,42)(H,38,41)

InChI key:
VVFZXPZWVJMYPX-UHFFFAOYSA-N

Img

Sigma Aldrich

76070

~40% Pd basis...


Quality Level:
100

form:
powder or crystals

reaction suitability:
reagent type: catalystcore: palladium

functional group:
__

storage temp.:
__

SMILES string:
O.O.[Pd++].[O-][N+]([O-])=O.[O-][N+]([O-])=O

InChI:
1S/2NO3.2H2O.Pd/c2*2-1(3)4;;;/h;;2*1H2;/q2*-1;;;+2

InChI key:
JUBNUQXDQDMSKL-UHFFFAOYSA-N

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Sigma Aldrich

76070

~40% Pd basis...


Quality Level:
100

form:
powder or crystals

reaction suitability:
reagent type: catalystcore: palladium

functional group:
__

storage temp.:
__

SMILES string:
O.O.[Pd++].[O-][N+]([O-])=O.[O-][N+]([O-])=O

InChI:
1S/2NO3.2H2O.Pd/c2*2-1(3)4;;;/h;;2*1H2;/q2*-1;;;+2

InChI key:
JUBNUQXDQDMSKL-UHFFFAOYSA-N