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SDS
760676

Dibenzocyclooctyne-PEG4-maleimide

for Copper-free Click Chemistry

Manufacturer: Sigma Aldrich

Synonym(S): Polyethylene glycol, DBCO-PEG4-maleimide

Select a Size

Pack Size SKU Availability Price
1 MG 760676-1-MG In Stock ₹ 2,662.95
5 MG 760676-5-MG In Stock ₹ 8,595.05
50 MG 760676-50-MG In Stock ₹ 32,810.58

760676 - 1 MG

₹ 2,662.95

In Stock

Quantity

1

Base Price: ₹ 2,662.95

GST (18%): ₹ 479.331

Total Price: ₹ 3,142.281

form

solid

reaction suitability

reaction type: click chemistryreagent type: cross-linking reagent

functional group

maleimide

storage temp.

−20°C

SMILES string

O=C(CCNC(CCOCCOCCOCCOCCNC(CCN1C(C=CC1=O)=O)=O)=O)N2CC3=C(C=CC=C3)C#CC4=C2C=CC=C4

InChI

1S/C36H42N4O9/c41-32(14-18-39-34(43)11-12-35(39)44)38-17-20-47-22-24-49-26-25-48-23-21-46-19-15-33(42)37-16-13-36(45)40-27-30-7-2-1-5-28(30)9-10-29-6-3-4-8-31(29)40/h1-8,11-12H,13-27H2,(H,37,42)(H,38,41)

InChI key

VVFZXPZWVJMYPX-UHFFFAOYSA-N

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Description

  • Application: Maleimide functionalized cyclooctyne derivative for incorporation of the cyclooctyne moiety into thiol containing compounds or biomolecules. Cyclooctynes are useful in strain-promoted copper-free azide-alkyne cycloaddition reactions. This dibenzocyclooctyne will react with azide functionalized compounds or biomolecules without the need for a Cu(I) catalyst to result in a stable triazole linkage. The PEG lipophilic spacer helps to reduce aggregation and precipitation problems when labeling biomolecules. Applications Include: Protein-peptide conjugatesAntibody-enzyme or antibody-drug conjugatesProtein or peptide-oligonucleotide conjugatesSurface modification

SAFETY INFORMATION

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Compare Similar Items

Show Difference

Img

Sigma Aldrich

760676

for Copper-free Click Chemistry...

form:
solid
reaction suitability:
reaction type: click chemistryreagent type: cross-linking reagent
functional group:
maleimide
storage temp.:
−20°C
SMILES string:
O=C(CCNC(CCOCCOCCOCCOCCNC(CCN1C(C=CC1=O)=O)=O)=O)N2CC3=C(C=CC=C3)C#CC4=C2C=CC=C4
InChI:
1S/C36H42N4O9/c41-32(14-18-39-34(43)11-12-35(39)44)38-17-20-47-22-24-49-26-25-48-23-21-46-19-15-33(42)37-16-13-36(45)40-27-30-7-2-1-5-28(30)9-10-29-6-3-4-8-31(29)40/h1-8,11-12H,13-27H2,(H,37,42)(H,38,41)
InChI key:
VVFZXPZWVJMYPX-UHFFFAOYSA-N

Img

Sigma Aldrich

76070

~40% Pd basis...

form:
powder or crystals
reaction suitability:
reagent type: catalystcore: palladium
functional group:
__
storage temp.:
__
SMILES string:
O.O.[Pd++].[O-][N+]([O-])=O.[O-][N+]([O-])=O
InChI:
1S/2NO3.2H2O.Pd/c2*2-1(3)4;;;/h;;2*1H2;/q2*-1;;;+2
InChI key:
JUBNUQXDQDMSKL-UHFFFAOYSA-N

Img

Sigma Aldrich

76070

~40% Pd basis...

form:
powder or crystals
reaction suitability:
reagent type: catalystcore: palladium
functional group:
__
storage temp.:
__
SMILES string:
O.O.[Pd++].[O-][N+]([O-])=O.[O-][N+]([O-])=O
InChI:
1S/2NO3.2H2O.Pd/c2*2-1(3)4;;;/h;;2*1H2;/q2*-1;;;+2
InChI key:
JUBNUQXDQDMSKL-UHFFFAOYSA-N

Img

Sigma Aldrich

760706

for Copper-free Click Chemistry...

form:
solid
reaction suitability:
reaction type: click chemistryreagent type: cross-linking reagent
functional group:
__
storage temp.:
−20°C
SMILES string:
CC[NH+](CC)CC.[O-]S(=O)(=O)C(CNC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12)C(=O)NCCC(=O)N3Cc4ccccc4C#Cc5ccccc35
InChI:
1S/C31H35N5O7S2.C6H15N/c37-27(12-6-5-11-25-29-23(19-44-25)34-31(40)35-29)33-17-26(45(41,42)43)30(39)32-16-15-28(38)36-18-22-9-2-1-7-20(22)13-14-21-8-3-4-10-24(21)36;1-4-7(5-2)6-3/h1-4,7-10,23,25-26,29H,5-6,11-12,15-19H2,(H,32,39)(H,33,37)(H2,34,35,40)(H,41,42,43);4-6H2,1-3H3/t23-,25-,26?,29-;/m0./s1
InChI key:
RACLEVCKGUBCTH-GESOYTMLSA-N