5545550
Tocris Bioscience™ ERK5-IN-1
Potent and selective ERK5 inhibitor
Manufacturer: Fischer Scientific
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Purity
>98%
Description
ERK5-IN-1
Molecular Weight (g/mol)
638.8
Product Type
ERK5-IN-1
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Description
- Potent and selective ERK5 inhibitor; inhibits EGFR-induced ERK5 autophosphorylation (EC50 = 90 nM) and ERK5 enzymatic activity (IC50 = 162 nM)
- Exhibits at least 30-fold selectivity for ERK5 over LRRK2 in a cell based assay
- Also selective for ERK5 over a panel of other kinases
- Orally bioavailable.
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Purity: >98%
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