PEP007

Invitrogen™ Rat Estrogen Receptor beta (aa 467-485) Synthetic Peptide

Manufacturer: Invitrogen™

Select a Size

Pack Size SKU Availability Price
Each of 1 PEP007-Each-of-1 In Stock ₹ 16,675.64

PEP007 - Each of 1

₹ 16,675.64

In Stock

Quantity

1

Base Price: ₹ 16,675.64

GST (18%): ₹ 3,001.615

Total Price: ₹ 19,677.255

Gene ID (Entrez)

25149

Purification Method

purified

Common Name

Rat Estrogen Receptor beta (aa 467-485)

Content And Storage

-20°C. Avoid freeze-thaw cycles.

Format

Lyophilized

For Use With (Application)

Control

Lyophilized

Yes

Product Type

Peptide

Regulatory Status

RUO - research use only

Species

Rat

Accession Number

Q62986

Concentration

0.5 mg/mL

Description

Synthetic Peptide

Formulation

peptide with no preservative

Gene Symbol

Esr2

Preservative

No preservative

Quantity

50 μg

Sequence

C - S - S - T - E - D - S - K - N - K - E - S - S - Q - N - L - Q - S - Q

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Description

  • Rat Estrogen Receptor beta (residues 467-485) Synthetic Peptide, PEP-007, from Invitrogen
  • Estrogen Receptor beta (ER beta, NR3A2) protein is approximately 55kD, though multiple isoforms ranging from 36-59kD have been described
  • Human ER beta was initially cloned and characterized from testis
  • Estrogen Receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of nuclear receptors
  • The estrogen receptor is a ligand-activated transcription factor, that when bound to estrogen hormone, induces a conformational change that allows dimerization and binding to estrogen response elements (ERE) in DNA
  • When bound to EREs, ER can positively or negatively regulate gene transcription through the recruitment of coactivator or corepressor proteins
  • There are two different forms of the estrogen receptor, alpha and beta, encoded by separate genes (ESR1 and ESR2, respectively)
  • Estrogen receptor beta (ER beta) binds estrogens with an affinity similar to that of estrogen receptor alpha
  • Some ER beta isoforms dominantly inhibit the activity of estrogen receptor alpha in reproductive tissues
  • ER beta is found widely in many tissues throughout the body and can act as a potent tumor suppressor, playing a crucial role in many cancer types such as prostate cancer, autism spectrum disorder, medullary thyroid carcinoma, De Quervain Disease and risk of cardiovascular disease
  • PEP-007 is a synthetic peptide whose sequence is from the C-terminal end of the rat estrogen receptor beta (ER beta)
  • The 19 amino acid sequence extends from amino acids 467 to 485 of ER beta
  • The sequence of PEP-007 is (amino to carboxy terminus): C-S-S-T-E-D-S-K-N-K-E-S-S-Q-N-L-Q-S-QThis peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product and the mouse and rat ER beta, catalog &Num PA1-310B
  • Using a solution with equal weights per unit volume of peptide and corresponding antibody will yield a solution with a large molar excess of peptide that is able to competitively bind the antibody.Reconstitute with 0.1 mL of distilled water.

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Invitrogen™

PEP007

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Gene ID (Entrez):
25149

Purification Method:
purified

Common Name:
Rat Estrogen Receptor beta (aa 467-485)

Content And Storage:
-20°C. Avoid freeze-thaw cycles.

Format:
Lyophilized

For Use With (Application):
Control

Lyophilized:
Yes

Product Type:
Peptide

Regulatory Status:
RUO - research use only

Species:
Rat

Accession Number:
Q62986

Concentration:
0.5 mg/mL

Description:
Synthetic Peptide

Formulation:
peptide with no preservative

Gene Symbol:
Esr2

Preservative:
No preservative

Quantity:
50 μg

Sequence:
C - S - S - T - E - D - S - K - N - K - E - S - S - Q - N - L - Q - S - Q

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Gene ID (Entrez):
9131

Purification Method:
purified

Common Name:
Human AIF

Content And Storage:
-20°C

Format:
Liquid

For Use With (Application):
Blocking Assay, Control

Lyophilized:
No

Product Type:
Peptide

Regulatory Status:
RUO - research use only

Species:
Human

Accession Number:
O95831

Concentration:
200 μg/mL

Description:
Synthetic Peptide

Formulation:
PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2

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Preservative:
0.02% sodium azide

Quantity:
50 μg

Sequence:
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Purification Method:
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Common Name:
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Content And Storage:
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Format:
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For Use With (Application):
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Lyophilized:
No

Product Type:
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Regulatory Status:
RUO - research use only

Species:
Human

Accession Number:
__

Concentration:
200 μg/mL

Description:
Synthetic Peptide

Formulation:
PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2

Gene Symbol:
CASP13

Preservative:
0.02% sodium azide

Quantity:
50 μg

Sequence:
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Gene ID (Entrez):
25825

Purification Method:
purified

Common Name:
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Content And Storage:
-20°C

Format:
Liquid

For Use With (Application):
Blocking Assay, Control

Lyophilized:
No

Product Type:
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Regulatory Status:
RUO - research use only

Species:
Human

Accession Number:
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Concentration:
200 μg/mL

Description:
Synthetic Peptide

Formulation:
PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2

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Preservative:
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Quantity:
50 μg

Sequence:
__