PEP0418
Invitrogen™ Human PKR Synthetic Peptide
Manufacturer: Invitrogen™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PEP0418-Each-of-1 | In Stock | ₹ 16,247.84 |
PEP0418 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 16,247.84
GST (18%): ₹ 2,924.611
Total Price: ₹ 19,172.451
Gene ID (Entrez)
5610
Purification Method
purified
Common Name
Human PKR
Content And Storage
-20°C
Format
Liquid
For Use With (Application)
Blocking Assay, Control
Lyophilized
No
Product Type
Peptide
Regulatory Status
RUO - research use only
Species
Human
Accession Number
P19525
Concentration
200 μg/mL
Description
Synthetic Peptide
Formulation
PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
Gene Symbol
EIF2AK2
Preservative
0.02% sodium azide
Quantity
50 μg
Storage Buffer
PBS
Related Products
Description
- PKR Synthetic Peptide, PEP-0418, from Invitrogen
- PKR is a 68 kDa protein and an IFN-induced serine/threonine protein kinase consisting of two N-terminal RNA-binding regulatory domains and a functional C-terminal serine/threonine protein kinase domain
- Activated by dsRNA produced during viral infections, PKR plays a key role in IFN induced-innate antiviral response, virus-induced apoptosis, cell growth and differentiation
- Upon activation, PKR gets autophosphorylated and catalyzes the phosphorylation of elF2 alpha subunit, which leads to an inhibition of protein synthesis
- PKR induces apoptosis by up-regulating Fas expression and mediates FADD/Caspase-8 death signaling pathway
- Upon viral infection, it functions as a dual protein, sequentially activating both cell survival and cell death pathways using kinase independent and dependent strategies
- PRKR regulates multiple pathways which include NF-kappaB activation, p53, p38, and PDGF signaling pathway
- PKR has been implicated in tumor suppression and malignancy
- To evade the antiviral effects of PKR, viruses have evolved multiple mechanisms, such as the inhibition of PKR by the non-structural protein (NS1) of the influenza virus
- More recently, PKR has been implicated in several neurodegenerative diseases including Alzheimer, Huntington, and amyotrophic lateral sclerosis
- This peptide corresponds to 14 amino acids near the amino terminus of human PKR.PEP-0418 can be used as a blocking peptide with polyclonal antibody PA5-20284.
Compare Similar Items
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Gene ID (Entrez): 5610
Purification Method: purified
Common Name: Human PKR
Content And Storage: -20°C
Format: Liquid
For Use With (Application): Blocking Assay, Control
Lyophilized: No
Product Type: Peptide
Regulatory Status: RUO - research use only
Species: Human
Accession Number: P19525
Concentration: 200 μg/mL
Description: Synthetic Peptide
Formulation: PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
Gene Symbol: EIF2AK2
Preservative: 0.02% sodium azide
Quantity: 50 μg
Storage Buffer: PBS
Gene ID (Entrez):
5610
Purification Method:
purified
Common Name:
Human PKR
Content And Storage:
-20°C
Format:
Liquid
For Use With (Application):
Blocking Assay, Control
Lyophilized:
No
Product Type:
Peptide
Regulatory Status:
RUO - research use only
Species:
Human
Accession Number:
P19525
Concentration:
200 μg/mL
Description:
Synthetic Peptide
Formulation:
PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
Gene Symbol:
EIF2AK2
Preservative:
0.02% sodium azide
Quantity:
50 μg
Storage Buffer:
PBS
Gene ID (Entrez): 6591
Purification Method: purified
Common Name: Human SLUG
Content And Storage: -20°C
Format: Liquid
For Use With (Application): Blocking Assay, Control
Lyophilized: No
Product Type: Peptide
Regulatory Status: RUO - research use only
Species: Human
Accession Number: O43623
Concentration: 200 μg/mL
Description: Synthetic Peptide
Formulation: PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
Gene Symbol: SNAI2
Preservative: 0.02% sodium azide
Quantity: 50 μg
Storage Buffer: PBS
Gene ID (Entrez):
6591
Purification Method:
purified
Common Name:
Human SLUG
Content And Storage:
-20°C
Format:
Liquid
For Use With (Application):
Blocking Assay, Control
Lyophilized:
No
Product Type:
Peptide
Regulatory Status:
RUO - research use only
Species:
Human
Accession Number:
O43623
Concentration:
200 μg/mL
Description:
Synthetic Peptide
Formulation:
PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
Gene Symbol:
SNAI2
Preservative:
0.02% sodium azide
Quantity:
50 μg
Storage Buffer:
PBS
Gene ID (Entrez): 8600
Purification Method: purified
Common Name: Human CD254 (RANK Ligand) (soluble)
Content And Storage: -20°C
Format: Liquid
For Use With (Application): Blocking Assay, Control
Lyophilized: No
Product Type: Peptide
Regulatory Status: RUO - research use only
Species: Human
Accession Number: O14788
Concentration: 200 μg/mL
Description: Synthetic Peptide
Formulation: PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
Gene Symbol: TNFSF11
Preservative: 0.02% sodium azide
Quantity: 50 μg
Storage Buffer: PBS
Gene ID (Entrez):
8600
Purification Method:
purified
Common Name:
Human CD254 (RANK Ligand) (soluble)
Content And Storage:
-20°C
Format:
Liquid
For Use With (Application):
Blocking Assay, Control
Lyophilized:
No
Product Type:
Peptide
Regulatory Status:
RUO - research use only
Species:
Human
Accession Number:
O14788
Concentration:
200 μg/mL
Description:
Synthetic Peptide
Formulation:
PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
Gene Symbol:
TNFSF11
Preservative:
0.02% sodium azide
Quantity:
50 μg
Storage Buffer:
PBS
Gene ID (Entrez): 867
Purification Method: purified
Common Name: Human c-Cbl
Content And Storage: -20°C
Format: Liquid
For Use With (Application): Blocking Assay, Control
Lyophilized: No
Product Type: Peptide
Regulatory Status: RUO - research use only
Species: Human
Accession Number: P22681
Concentration: 200 μg/mL
Description: Synthetic Peptide
Formulation: PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
Gene Symbol: CBL
Preservative: 0.02% sodium azide
Quantity: 50 μg
Storage Buffer: PBS
Gene ID (Entrez):
867
Purification Method:
purified
Common Name:
Human c-Cbl
Content And Storage:
-20°C
Format:
Liquid
For Use With (Application):
Blocking Assay, Control
Lyophilized:
No
Product Type:
Peptide
Regulatory Status:
RUO - research use only
Species:
Human
Accession Number:
P22681
Concentration:
200 μg/mL
Description:
Synthetic Peptide
Formulation:
PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
Gene Symbol:
CBL
Preservative:
0.02% sodium azide
Quantity:
50 μg
Storage Buffer:
PBS