C10422

Invitrogen™ CellROX™ Deep Red Reagent, for oxidative stress detection

Manufacturer: Invitrogen™

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Pack Size SKU Availability Price
Each of 1 C10422-Each-of-1 In Stock ₹ 51,507.12

C10422 - Each of 1

₹ 51,507.12

In Stock

Quantity

1

Base Price: ₹ 51,507.12

GST (18%): ₹ 9,271.282

Total Price: ₹ 60,778.402

Color

Deep Red

Quantity

250 μL

For Use With (Equipment)

Imaging, HCS, Cytometer

Detection Method

Live Cell Imaging

Indicator

Oxidative stress

Format

Liquid

Content And Storage

Store at ≤–20°C. Protect from light and desiccate.

Concentration

2.5 mM stabilized solution in DMSO

Excitation/Emission

644/665 nm

Product Line

CellROX™

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Description

  • CellROX™ Deep Red Reagent is a novel fluorogenic probe for measuring cellular oxidative stress in both live and fixed cell imaging, with absorption/emission maxima at ∼644/665 nm
  • The cell-permeant dye is non-fluorescent while in a reduced state, and exhibits bright fluorescence upon oxidation by reactive oxygen species (ROS)
  • Features of the CellROX™ Deep Red Reagent: • Optimized probe for detection of oxidative stress in cells • Simple protocol that can be used with other live cell dyes and GFP • Compatible with both live cell fluorescence-imaging and formaldehyde-based fixation methods Substrate Specifics The CellROX™ Deep Red reagent is a novel cell-permeant dye with absorption/emission maxima of ∼644/665 nm
  • CellROX™ Deep Red reagent is non-fluorescent while in a reduced state and becomes fluorescent upon oxidation by reactive oxygen species with emission maxima ∼665 nm that is measurable by fluorescent imaging, high content imaging, fluorescent plate readers, or flow cytometry
  • Oxidative Stress Detection with CellROX™ Deep Red Reagent Oxidative stress results from an imbalance between production of reactive oxygen species (ROS) and the ability of cells to scavenge them
  • ROS play an important role in the progression of several diseases including inflammation, atherosclerosis, aging, and age-related degenerative disorders
  • CellROX™ Deep Red Reagent can detect the oxidative stress in cells by reacting with ROS to become brightly fluorescent
  • Simple, Robust Protocol The protocol to use this reagent is simple and the bright deep red fluorescence signal is compatible with other live cell dyes and GFP, making it useful in multiplex fluorescence assays to measure a variety of cellular phenomena, including parameters related to cytotoxicity and cell death (Figure 4 below)
  • Furthermore, unlike many other ROS sensors, such as H2DCFDA, the signal from CellROX™ Deep Red is retained after formaldehyde fixation for flexibility with the assay and improved workflows compared to those based on classic dyes for ROS detection
  • Order Info Shipping Condition: Wet Ice

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Show Difference

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Invitrogen™

C10422

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Color:
Deep Red

Quantity:
250 μL

For Use With (Equipment):
Imaging, HCS, Cytometer

Detection Method:
Live Cell Imaging

Indicator:
Oxidative stress

Format:
Liquid

Content And Storage:
Store at ≤–20°C. Protect from light and desiccate.

Concentration:
2.5 mM stabilized solution in DMSO

Excitation/Emission:
644/665 nm

Product Line:
CellROX™

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For Use With (Equipment):
Fluorescence Microscope, High Content Instrument

Detection Method:
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Indicator:
__

Format:
__

Content And Storage:
100 μL, 2 mM solution in DMSO. Store (at ≤-20°C, desiccate and protect from light.)

Concentration:
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Excitation/Emission:
∼502/530 nm

Product Line:
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Color:
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50

For Use With (Equipment):
Flow Cytometer

Detection Method:
Fluorescence

Indicator:
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Format:
Tube(s)

Content And Storage:
Contains EdU (5-ethynyl-2' -deoxyuridine), Alexa Fluor™ 647 azide, anhydrous dimethylsulfoxide (DMSO), Click-iT™ fixative, Click-iT™ saponin-based permeabilization and wash buffer, copper (II) sulfate,, and Click-iT™ EdU buffer additive.Store at 2°C to 8°CDessicate and protect from light.

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Excitation/Emission:
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Color:
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Quantity:
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For Use With (Equipment):
Flow Cytometer

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Fluorescence

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Content And Storage:
Contains EdU (5-ethynyl-2' -deoxyuridine), Alexa Fluor™ 488 azide, anhydrous dimethylsulfoxide (DMSO), Click-iT™ fixative, Click-iT™ saponin-based permeabilization and wash buffer, copper (II) sulfate,, and Click-iT™ EdU buffer additive.Store at 2°C to 8°CDessicate and protect from light.

Concentration:
__

Excitation/Emission:
__

Product Line:
Click-iT™