K1529
Thermo Scientific™ GeneBLAzer™ CNR1-Gα15-NFAT-blaCHO-K1 Cells
Manufacturer: Thermo Scientific™
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | K1529-Each-of-1 | In Stock | ₹ 9,05,224.80 |
K1529 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 9,05,224.80
GST (18%): ₹ 1,62,940.464
Total Price: ₹ 10,68,165.264
Accession Number
NM_016083
Cell State
Dividing Cells
Detection Method
Fluorescence
Gene Symbol
CNR1
Product Line
GeneBLAzer™
Reporter Gene
BLA (Beta-Lactamase)
Type
CHO-K1 Cells
System Type
GeneBLAzer™
Assay Entry
Cell-based beta lactamase reporter gene
Content And Storage
LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol.Includes:• GeneBLAzer™ CNR1-Gα15-NFAT-blaCHO-K1 cells• GeneBLAzer™ CNR1-Gα15-NFAT-blaCHO-K1 Assay Protocol• Certificate of AnalysisThe GeneBLAzer™ CNR1-Gα15-NFAT-blaCHO-K1 cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.
For Use With (Application)
FRET
Population Status
Single Cell Clone Origin
Quantity
2 x 106Cells
Target Entry
CNR1
Cell Line
CHO-K1
Druggable Target
GPCR
Related Products
Description
- GeneBLAzer™ CNR1-Gα15-NFAT- bla CHO-K1 cells contain the human Cannabinoid Receptor 1 (CNR1) stably integrated into the GeneBLAzer™ Gα15-NFAT- bla CHO-K1 cell line
- GeneBLAzer™ Gα15-NFAT- bla CHO-K1 cells (Cat
- No
- K1537) contain a beta-lactamase reporter gene under control of the Nuclear Factor of Activated T-cells (NFAT) response element and the Promiscuous G protein, Gα15
- The GeneBLAzer™ CNR1-Gα15-NFAT- bla CHO-K1 cells are functionally validated for Z' and EC 50 concentrations of CP-55,940
- In addition, GeneBLAzer™ CNR1-Gα15-NFAT- bla CHO-K1 cells have been tested for assay performance under variable conditions
- These data are found in the Validation & Assay Performance Summary
- The cannabinoid receptors are a family of GPCRs named after their endogenous ligand Delta9-tetrahydrocannabinol (Delta9-THC)
- Delta9-THC is the psychoactive component of Cannabis sativa (marijuana)
- CNR1 is present in many tissues throughout the body
- The highest concentrations of cannabinoid receptors are in the neurons of the brain, the hippocampus, cerebral cortex, basal ganglia, and the cerebellum
- Low-level expression occurs in the lung, testis, and uterus, as well as vascular tissue
- Delta9-THC and CP55,940 are endogenous agonists of the CNR1 pathway
- Several Delta9-THC and CP55,940 analogs have been synthesized, including HU 210 and WIN 55,212-2
- The CNR1 and CNR2 receptors have equal affinity for cannabinoid agonists, but several antagonists that are subtype selective have been synthesized
- Examples of these antagonists are AM251, LY-320135, and SR 141716A
- For Academic pricing please login or contact us at discoverysciences@invitrogen.com.
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Accession Number: NM_016083
Cell State: Dividing Cells
Detection Method: Fluorescence
Gene Symbol: CNR1
Product Line: GeneBLAzer™
Reporter Gene: BLA (Beta-Lactamase)
Type: CHO-K1 Cells
System Type: GeneBLAzer™
Assay Entry: Cell-based beta lactamase reporter gene
Content And Storage: LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol.Includes:• GeneBLAzer™ CNR1-Gα15-NFAT-blaCHO-K1 cells• GeneBLAzer™ CNR1-Gα15-NFAT-blaCHO-K1 Assay Protocol• Certificate of AnalysisThe GeneBLAzer™ CNR1-Gα15-NFAT-blaCHO-K1 cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.
For Use With (Application): FRET
Population Status: Single Cell Clone Origin
Quantity: 2 x 106Cells
Target Entry: CNR1
Cell Line: CHO-K1
Druggable Target: GPCR
Accession Number:
NM_016083
Cell State:
Dividing Cells
Detection Method:
Fluorescence
Gene Symbol:
CNR1
Product Line:
GeneBLAzer™
Reporter Gene:
BLA (Beta-Lactamase)
Type:
CHO-K1 Cells
System Type:
GeneBLAzer™
Assay Entry:
Cell-based beta lactamase reporter gene
Content And Storage:
LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol.Includes:• GeneBLAzer™ CNR1-Gα15-NFAT-blaCHO-K1 cells• GeneBLAzer™ CNR1-Gα15-NFAT-blaCHO-K1 Assay Protocol• Certificate of AnalysisThe GeneBLAzer™ CNR1-Gα15-NFAT-blaCHO-K1 cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.
For Use With (Application):
FRET
Population Status:
Single Cell Clone Origin
Quantity:
2 x 106Cells
Target Entry:
CNR1
Cell Line:
CHO-K1
Druggable Target:
GPCR
Accession Number: NM_001838.2
Cell State: Dividing Cells
Detection Method: Fluorescence
Gene Symbol: CCR7
Product Line: Tango™
Reporter Gene: BLA (Beta-Lactamase)
Type: U2OS Cell
System Type: Tango™
Assay Entry: Cell-based beta-arrestin recruitment
Content And Storage: LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol.Includes:• Tango™ CCR7-bla U2OS cells• Tango™ CCR7-bla U2OS Assay Protocol• Certificate of AnalysisThe Tango™ CCR7-bla U2OS cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.
For Use With (Application): __
Population Status: Pool of Stable Cells
Quantity: 2 x 106Cells
Target Entry: CCR7
Cell Line: U2OS
Druggable Target: GPCR
Accession Number:
NM_001838.2
Cell State:
Dividing Cells
Detection Method:
Fluorescence
Gene Symbol:
CCR7
Product Line:
Tango™
Reporter Gene:
BLA (Beta-Lactamase)
Type:
U2OS Cell
System Type:
Tango™
Assay Entry:
Cell-based beta-arrestin recruitment
Content And Storage:
LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol.Includes:• Tango™ CCR7-bla U2OS cells• Tango™ CCR7-bla U2OS Assay Protocol• Certificate of AnalysisThe Tango™ CCR7-bla U2OS cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.
For Use With (Application):
__
Population Status:
Pool of Stable Cells
Quantity:
2 x 106Cells
Target Entry:
CCR7
Cell Line:
U2OS
Druggable Target:
GPCR
Accession Number: NM_001462
Cell State: Dividing Cells
Detection Method: Fluorescence
Gene Symbol: FPRL-1
Product Line: GeneBLAzer™
Reporter Gene: BLA (Beta-Lactamase)
Type: __
System Type: GeneBLAzer™
Assay Entry: Cell-based beta lactamase reporter gene
Content And Storage: LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol.Includes:• GeneBLAzer™ FPRL-1-Gα15-NFAT-blaCHO-K1 cells• GeneBLAzer™ FPRL-1-Gα15-NFAT-blaCHO-K1 Assay Protocol• Certificate of AnalysisThe GeneBLAzer™ FPRL-1-Gα15-NFAT-blaCHO-K1 cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.
For Use With (Application): FRET
Population Status: Single Cell Clone Origin
Quantity: 2 x 106Cells
Target Entry: FPRL-1
Cell Line: CHO-K1
Druggable Target: GPCR
Accession Number:
NM_001462
Cell State:
Dividing Cells
Detection Method:
Fluorescence
Gene Symbol:
FPRL-1
Product Line:
GeneBLAzer™
Reporter Gene:
BLA (Beta-Lactamase)
Type:
__
System Type:
GeneBLAzer™
Assay Entry:
Cell-based beta lactamase reporter gene
Content And Storage:
LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol.Includes:• GeneBLAzer™ FPRL-1-Gα15-NFAT-blaCHO-K1 cells• GeneBLAzer™ FPRL-1-Gα15-NFAT-blaCHO-K1 Assay Protocol• Certificate of AnalysisThe GeneBLAzer™ FPRL-1-Gα15-NFAT-blaCHO-K1 cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.
For Use With (Application):
FRET
Population Status:
Single Cell Clone Origin
Quantity:
2 x 106Cells
Target Entry:
FPRL-1
Cell Line:
CHO-K1
Druggable Target:
GPCR
Accession Number: NM_000912
Cell State: Dividing Cells
Detection Method: Fluorescence
Gene Symbol: OPRK1
Product Line: GeneBLAzer™
Reporter Gene: BLA (Beta-Lactamase)
Type: CHO-K1 Cells
System Type: GeneBLAzer™
Assay Entry: Cell-based beta lactamase reporter gene
Content And Storage: LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol.Includes:• GeneBLAzer™ OPRK1 Gqo5 NFAT-blaCHO-K1 cells• GeneBLAzer™ OPRK1 Gqo5 NFAT-blaCHO-K1 Assay Protocol• Certificate of AnalysisThe GeneBLAzer™ OPRK1 Gqo5 NFAT-blaCHO-K1 cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.
For Use With (Application): FRET
Population Status: Single Cell Clone Origin
Quantity: 2 x 106Cells
Target Entry: OPRK1
Cell Line: CHO-K1
Druggable Target: GPCR
Accession Number:
NM_000912
Cell State:
Dividing Cells
Detection Method:
Fluorescence
Gene Symbol:
OPRK1
Product Line:
GeneBLAzer™
Reporter Gene:
BLA (Beta-Lactamase)
Type:
CHO-K1 Cells
System Type:
GeneBLAzer™
Assay Entry:
Cell-based beta lactamase reporter gene
Content And Storage:
LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol.Includes:• GeneBLAzer™ OPRK1 Gqo5 NFAT-blaCHO-K1 cells• GeneBLAzer™ OPRK1 Gqo5 NFAT-blaCHO-K1 Assay Protocol• Certificate of AnalysisThe GeneBLAzer™ OPRK1 Gqo5 NFAT-blaCHO-K1 cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.
For Use With (Application):
FRET
Population Status:
Single Cell Clone Origin
Quantity:
2 x 106Cells
Target Entry:
OPRK1
Cell Line:
CHO-K1
Druggable Target:
GPCR