K1667

Thermo Scientific™ CellSensor™ NFkB-blaME-180 Cell Line

Manufacturer: Thermo Scientific™

Select a Size

Pack Size SKU Availability Price
Each of 1 K1667-Each-of-1 In Stock ₹ 9,05,224.80

K1667 - Each of 1

₹ 9,05,224.80

In Stock

Quantity

1

Base Price: ₹ 9,05,224.80

GST (18%): ₹ 1,62,940.464

Total Price: ₹ 10,68,165.264

Assay Entry

Cell-based beta lactamase reporter gene

Content And Storage

CellSensor™ Cell Lines are shipped on dry ice. Store in liquid nitrogen immediately upon receipt, or thaw for immediate use.

Quantity

1 Vial

Type

Cell Line

System Type

CellSensor™

Cell State

Dividing Cells

Product Line

CellSensor™

Target Entry

TNF alpha, NIK, TLR, I kappa B, IRAK, IKK, NF-kappa B pathway

Cell Line

ME-180

Druggable Target

Signaling Pathway

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Description

  • The CellSensor™ NFκB-bla ME-180 cell line contains a beta-lactamase reporter gene under control of the Nuclear Factor Kappa B (NFκB) response element stably integrated into ME-180 cells
  • The cell line was created through fluorescence activated cell sorting (FACS) of cells responsive to stimulation of the NFκB pathway with tumor necrosis factor alpha (TNFα)
  • The cell line was validated for DMSO tolerance, incubation time with stimulant, and substrate loading conditions
  • The CellSensor™ NFκB-bla ME-180 cell line responds to agonist treatment as expected from literature and can be adapted for high-throughput screening for agonists or antagonists of the NFκB pathway with compound libraries
  • Candidate drugs can also be tested for dose response against this cell line
  • Academic and non-profit customers, please inquire for special pricing.

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Assay Entry:
Cell-based beta lactamase reporter gene

Content And Storage:
CellSensor™ Cell Lines are shipped on dry ice. Store in liquid nitrogen immediately upon receipt, or thaw for immediate use.

Quantity:
1 Vial

Type:
Cell Line

System Type:
CellSensor™

Cell State:
Dividing Cells

Product Line:
CellSensor™

Target Entry:
TNF alpha, NIK, TLR, I kappa B, IRAK, IKK, NF-kappa B pathway

Cell Line:
ME-180

Druggable Target:
Signaling Pathway

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