K1713
Thermo Scientific™ GeneBLAzer™ EDG3-Gα15-NFAT-blaHEK 293T Cells
Manufacturer: Thermo Scientific™
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | K1713-Each-of-1 | In Stock | ₹ 9,05,224.80 |
K1713 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 9,05,224.80
GST (18%): ₹ 1,62,940.464
Total Price: ₹ 10,68,165.264
Accession Number
NM_005226.2
Cell State
Dividing Cells
Detection Method
Fluorescence
Gene Symbol
EDG3
Product Line
GeneBLAzer™
Reporter Gene
BLA (Beta-Lactamase)
Cell Line
293T (HEK)
Druggable Target
GPCR
Assay Entry
Cell-based beta lactamase reporter gene
Content And Storage
LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol.Includes:• GeneBLAzer™ EDG3-Gα15-NFAT-blaHEK293T cells• GeneBLAzer™ EDG3-Gα15-NFAT-blaHEK293T Assay Protocol• Certificate of AnalysisThe GeneBLAzer™ EDG3-Gα15-NFAT-blaHEK293T cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.
For Use With (Application)
FRET
Population Status
Single Cell Clone Origin
Quantity
2 x 106Cells
Target Entry
EDG3
System Type
GeneBLAzer™
Related Products
Description
- Description GeneBLAzer™ EDG3-Gα15-NFAT- bla HEK293T cells contain the human Endothelial Differentiation Receptor 3 (EDG3) stably integrated into the GeneBLAzer™ EDG3-Gα15-NFAT- bla HEK293T cell line
- GeneBLAzer™ Gα15-NFAT- bla HEK293T cells (Cat
- No
- K1539) contain a beta-lactamase reporter gene under control of the Nuclear Factor of Activated T-cells (NFAT) response element and the Promiscuous G protein, Gα15
- The GeneBLAzer™ EDG3-Gα15-NFAT- bla HEK293T cells are functionally validated for Z' and EC 50 concentrations of S1P
- In addition, GeneBLAzer™ EDG3-Gα15-NFAT- bla HEK293T cells have been tested for assay performance under variable conditions
- These data are found in the Validation & Assay Performance Summary
- EDG-3/S1P-3(Sphingosine-1-Phosphate-3) is a Gq/Gi/Go/Gα13/Gα12 coupled GPCR
- EDG-3 has been shown to be responsible for bradycardia that has been induced in clinical trials as a side effect of the immunosuppressive drug FTY720 that targets EDG-1
- EDG-3 has also been shown to induce vasodilation in response to sphingosylphosphorylcholine (SPC), sphingosine-1-phosphate (S1P), and lysosulfatide (LSF)
- The EDG-3 Receptor has also been shown to play a cooperative or redundant role in angiogenesis with EDG-1
- For Academic pricing please login or contact us at discoverysciences@invitrogen.com.
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Accession Number: NM_005226.2
Cell State: Dividing Cells
Detection Method: Fluorescence
Gene Symbol: EDG3
Product Line: GeneBLAzer™
Reporter Gene: BLA (Beta-Lactamase)
Cell Line: 293T (HEK)
Druggable Target: GPCR
Assay Entry: Cell-based beta lactamase reporter gene
Content And Storage: LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol.Includes:• GeneBLAzer™ EDG3-Gα15-NFAT-blaHEK293T cells• GeneBLAzer™ EDG3-Gα15-NFAT-blaHEK293T Assay Protocol• Certificate of AnalysisThe GeneBLAzer™ EDG3-Gα15-NFAT-blaHEK293T cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.
For Use With (Application): FRET
Population Status: Single Cell Clone Origin
Quantity: 2 x 106Cells
Target Entry: EDG3
System Type: GeneBLAzer™
Accession Number:
NM_005226.2
Cell State:
Dividing Cells
Detection Method:
Fluorescence
Gene Symbol:
EDG3
Product Line:
GeneBLAzer™
Reporter Gene:
BLA (Beta-Lactamase)
Cell Line:
293T (HEK)
Druggable Target:
GPCR
Assay Entry:
Cell-based beta lactamase reporter gene
Content And Storage:
LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol.Includes:• GeneBLAzer™ EDG3-Gα15-NFAT-blaHEK293T cells• GeneBLAzer™ EDG3-Gα15-NFAT-blaHEK293T Assay Protocol• Certificate of AnalysisThe GeneBLAzer™ EDG3-Gα15-NFAT-blaHEK293T cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.
For Use With (Application):
FRET
Population Status:
Single Cell Clone Origin
Quantity:
2 x 106Cells
Target Entry:
EDG3
System Type:
GeneBLAzer™
Accession Number: NM_000913
Cell State: Dividing Cells
Detection Method: Fluorescence
Gene Symbol: OPRL1
Product Line: GeneBLAzer™
Reporter Gene: BLA (Beta-Lactamase)
Cell Line: FreeStyle 293-F Cells
Druggable Target: GPCR
Assay Entry: Cell-based beta lactamase reporter gene
Content And Storage: LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol.Includes:• GeneBLAzer™ OPRL1-Gqi5-NFAT-blaFreestyle 293F cells• GeneBLAzer™ OPRL1-Gqi5-NFAT-blaFreestyle 293F Assay Protocol• Certificate of AnalysisThe GeneBLAzer™ OPRL1-Gqi5-NFAT-blaFreestyle 293F cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.
For Use With (Application): FRET
Population Status: Single Cell Clone Origin
Quantity: 2 x 106Cells
Target Entry: OPRL1
System Type: GeneBLAzer™
Accession Number:
NM_000913
Cell State:
Dividing Cells
Detection Method:
Fluorescence
Gene Symbol:
OPRL1
Product Line:
GeneBLAzer™
Reporter Gene:
BLA (Beta-Lactamase)
Cell Line:
FreeStyle 293-F Cells
Druggable Target:
GPCR
Assay Entry:
Cell-based beta lactamase reporter gene
Content And Storage:
LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol.Includes:• GeneBLAzer™ OPRL1-Gqi5-NFAT-blaFreestyle 293F cells• GeneBLAzer™ OPRL1-Gqi5-NFAT-blaFreestyle 293F Assay Protocol• Certificate of AnalysisThe GeneBLAzer™ OPRL1-Gqi5-NFAT-blaFreestyle 293F cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.
For Use With (Application):
FRET
Population Status:
Single Cell Clone Origin
Quantity:
2 x 106Cells
Target Entry:
OPRL1
System Type:
GeneBLAzer™
Accession Number: NM_000706.3
Cell State: Dividing Cells
Detection Method: Fluorescence
Gene Symbol: AVPR1a
Product Line: GeneBLAzer™
Reporter Gene: BLA (Beta-Lactamase)
Cell Line: CHO-K1
Druggable Target: GPCR
Assay Entry: Cell-based beta lactamase reporter gene
Content And Storage: LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol.Includes:• GeneBLAzer™ AVPR1a-NFAT-blaCHO-K1 cells• GeneBLAzer™ AVPR1a-NFAT-blaCHO-K1 Assay Protocol• Certificate of AnalysisThe GeneBLAzer™ AVPR1a-NFAT-blaCHO-K1 cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.
For Use With (Application): FRET
Population Status: Single Cell Clone Origin
Quantity: 2 x 106cells
Target Entry: AVPR1A
System Type: GeneBLAzer™
Accession Number:
NM_000706.3
Cell State:
Dividing Cells
Detection Method:
Fluorescence
Gene Symbol:
AVPR1a
Product Line:
GeneBLAzer™
Reporter Gene:
BLA (Beta-Lactamase)
Cell Line:
CHO-K1
Druggable Target:
GPCR
Assay Entry:
Cell-based beta lactamase reporter gene
Content And Storage:
LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol.Includes:• GeneBLAzer™ AVPR1a-NFAT-blaCHO-K1 cells• GeneBLAzer™ AVPR1a-NFAT-blaCHO-K1 Assay Protocol• Certificate of AnalysisThe GeneBLAzer™ AVPR1a-NFAT-blaCHO-K1 cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.
For Use With (Application):
FRET
Population Status:
Single Cell Clone Origin
Quantity:
2 x 106cells
Target Entry:
AVPR1A
System Type:
GeneBLAzer™
Accession Number: NM_000740.2
Cell State: Dividing Cells
Detection Method: Fluorescence
Gene Symbol: M3
Product Line: GeneBLAzer™
Reporter Gene: BLA (Beta-Lactamase)
Cell Line: CHO-K1
Druggable Target: GPCR
Assay Entry: Cell-based beta lactamase reporter gene
Content And Storage: LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol.Includes:• GeneBLAzer™ M3-NFAT-blaCHO-K1 cells• GeneBLAzer™ M3-NFAT-blaCHO-K1 Assay Protocol• Certificate of AnalysisThe GeneBLAzer™ M3-NFAT-blaCHO-K1 cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.
For Use With (Application): FRET
Population Status: Single Cell Clone Origin
Quantity: 2 x 106Cells
Target Entry: M3
System Type: GeneBLAzer™
Accession Number:
NM_000740.2
Cell State:
Dividing Cells
Detection Method:
Fluorescence
Gene Symbol:
M3
Product Line:
GeneBLAzer™
Reporter Gene:
BLA (Beta-Lactamase)
Cell Line:
CHO-K1
Druggable Target:
GPCR
Assay Entry:
Cell-based beta lactamase reporter gene
Content And Storage:
LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol.Includes:• GeneBLAzer™ M3-NFAT-blaCHO-K1 cells• GeneBLAzer™ M3-NFAT-blaCHO-K1 Assay Protocol• Certificate of AnalysisThe GeneBLAzer™ M3-NFAT-blaCHO-K1 cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.
For Use With (Application):
FRET
Population Status:
Single Cell Clone Origin
Quantity:
2 x 106Cells
Target Entry:
M3
System Type:
GeneBLAzer™