K1754

Thermo Scientific™ Tango™ AGTRL1-blaU2OS Cells

Manufacturer: Thermo Scientific™

Select a Size

Pack Size SKU Availability Price
Each of 1 K1754-Each-of-1 In Stock ₹ 8,88,112.80

K1754 - Each of 1

₹ 8,88,112.80

In Stock

Quantity

1

Base Price: ₹ 8,88,112.80

GST (18%): ₹ 1,59,860.304

Total Price: ₹ 10,47,973.104

Accession Number

NM_005161

Cell State

Dividing Cells

Cytoplasmic Tail

Native Tail

Gene Symbol

AGTRL1

Product Line

GeneBLAzer™

Quantity

8 x 106Cells

Reporter Gene

BLA (Beta-Lactamase)

Cell Line

U2OS

Druggable Target

GPCR

Assay Entry

Cell-based beta-arrestin recruitment

Content And Storage

LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol.Includes:• Tango™ AGTRL1-bla U2OS cells• Tango™ AGTRL1-bla U2OS Assay Protocol• Certificate of AnalysisThe Tango™ AGTRL1-bla U2OS cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.

Detection Method

Fluorescence

Population Status

Single Cell Clone Origin

Protein Family

GPCR (G-Protein Coupled Receptors)

Readout

End Point

Target Entry

AGTRL1

System Type

Tango™

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Description

  • The Tango™ AGTRL1-bla U2OS cells contain the human Angtiotension-Like Receptor 1 (AGTRL1) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line
  • This parental cell line stably expresses a beta-arrestin/TEV protease fusion protein and the beta-lactamase (bla) reporter gene under the control of a UAS response element
  • The Tango™ AGTRL1-bla U2OS cells have been functionally validated for Z' factor and EC50 concentrations of established ligands
  • In addition, Tango™AGTRL1-bla U2OS cells have been tested for assay performance under variable conditions
  • These data are found in the Validation & Assay Performance Summary for each product.

Compare Similar Items

Show Difference

Img

Thermo Scientific™

K1754

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Accession Number:
NM_005161

Cell State:
Dividing Cells

Cytoplasmic Tail:
Native Tail

Gene Symbol:
AGTRL1

Product Line:
GeneBLAzer™

Quantity:
8 x 106Cells

Reporter Gene:
BLA (Beta-Lactamase)

Cell Line:
U2OS

Druggable Target:
GPCR

Assay Entry:
Cell-based beta-arrestin recruitment

Content And Storage:
LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol.Includes:• Tango™ AGTRL1-bla U2OS cells• Tango™ AGTRL1-bla U2OS Assay Protocol• Certificate of AnalysisThe Tango™ AGTRL1-bla U2OS cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.

Detection Method:
Fluorescence

Population Status:
Single Cell Clone Origin

Protein Family:
GPCR (G-Protein Coupled Receptors)

Readout:
End Point

Target Entry:
AGTRL1

System Type:
Tango™

Img

Thermo Scientific™

K1757

--


Accession Number:
NM_003775.1

Cell State:
Division-Arrested Cells

Cytoplasmic Tail:
Tail from GRPR GPCR

Gene Symbol:
EDG6

Product Line:
Tango™

Quantity:
8 x 106Cells

Reporter Gene:
BLA (Beta-Lactamase)

Cell Line:
U2OS

Druggable Target:
GPCR

Assay Entry:
Cell-based beta-arrestin recruitment

Content And Storage:
Each kit contains sufficient quantities of division arrested (DA) cells and substrate to assay 1 x 384 well plate. (Other materials are required separately; please refer to the protocol).Includes:• Tango™ EDG6-bla U2OS DA cells• LiveBLAzer™-FRET B/G Loading Kit, 70μg• Solution D• Tango™ EDG6-bla U2OS DA Assay Protocol• LiveBLAzer™-FRET B/G Loading Protocol• Certificate of AnalysisThe Tango™ EDG6-bla U2OS DA cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.

Detection Method:
Fluorescence

Population Status:
Pool of Stable Cells

Protein Family:
__

Readout:
__

Target Entry:
EDG6

System Type:
Tango™

Img

Thermo Scientific™

K1761

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Accession Number:
NM_004367.3

Cell State:
Dividing Cells

Cytoplasmic Tail:
Native Tail

Gene Symbol:
CCR6

Product Line:
Tango™

Quantity:
2 x 106Cells

Reporter Gene:
BLA (Beta-Lactamase)

Cell Line:
U2OS

Druggable Target:
GPCR

Assay Entry:
Cell-based beta-arrestin recruitment

Content And Storage:
K1761 Tango™ CCR6-bla U2OS cells(LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol).Includes:• Tango™ CCR6-bla U2OS cells• Tango™ CCR6-bla U2OS Assay Protocol• Certificate of AnalysisStorage:The Tango™ CCR6-bla U2OS cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.

Detection Method:
Fluorescence

Population Status:
Single Cell Clone Origin

Protein Family:
__

Readout:
__

Target Entry:
CCR6

System Type:
Tango™

Img

Thermo Scientific™

K1762

--


Accession Number:
NM_005161

Cell State:
Division-Arrested Cells

Cytoplasmic Tail:
Native Tail

Gene Symbol:
AGTRL1

Product Line:
GeneBLAzer™

Quantity:
1 Kit

Reporter Gene:
BLA (Beta-Lactamase)

Cell Line:
U2OS

Druggable Target:
GPCR

Assay Entry:
Cell-based beta-arrestin recruitment

Content And Storage:
Each kit contains sufficient quantities of division arrested (DA) cells and substrate to assay 1 x 384 well plate. (Other materials are required separately; please refer to the protocol).Includes:• Tango™ AGTRL1-bla U2OS DA cells• LiveBLAzer™-FRET B/G Loading Kit, 70 μg• Solution D• Tango™ AGTRL1-bla U2OS DA Assay Protocol• LiveBLAzer™-FRET B/G Loading Protocol• Certificate of AnalysisThe Tango™ AGTRL1-bla U2OS DA cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.

Detection Method:
Fluorescence

Population Status:
Single Cell Clone Origin

Protein Family:
GPCR (G-Protein Coupled Receptors)

Readout:
End Point

Target Entry:
AGTRL1

System Type:
Tango™