SRP3256
TPO from rat
Animal-component free, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture
Manufacturer: Sigma Aldrich
Synonym(S): MGDF, Megakaryocyte colony-stimulating factor, Thrombopoietin, c-MPL Ligand
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 10 μG | SRP3256-10-μG | In Stock | ₹ 49,750.20 |
SRP3256 - 10 μG
In Stock
Quantity
1
Base Price: ₹ 49,750.20
GST (18%): ₹ 8,955.036
Total Price: ₹ 58,705.236
biological source
rat
recombinant
expressed in E. coli
Assay
≥98% (HPLC)≥98% (SDS-PAGE)
form
lyophilized
potency
≤0.2 ng/mL ED50
mol wt
18.7 kDa
packaging
pkg of 10 μg
technique(s)
cell culture | mammalian: suitable
impurities
<0.1 EU/μg endotoxin, tested
color
white
Related Products
Description
- General description: TPO (thrombopoietin) is a hematopoietic cytokine expressed in multiple tissue types. It is predominantly produced by liver and kidney and acts as a ligand for the cell surface receptor c-mpl.[1][2]
- Biochem/physiol Actions: TPO (thrombopoietin) is the key regulator of thrombopoiesis for platelet lineage. In both mice and humans, inactivation of this gene results in significant decrease in number of mature platelets produced by marrow progenitors. Transgenic mice with increased expression of this protein show progressive fibrosis and osteosclerosis of the bone marrow, as well as histological changes in kidneys, leading to mesangioproliferative glomerulopathy.[1][2]
- Sequence: SPVPPACDPR LLNKLLRDSY LLHSRLSQCP DVNPLSIPVL LPAVDFSLGE WKTQTEQSKA QDILGAVSLL LEGVMAARGQ LEPSCLSSLL GQLSGQVRLL LGALQGLLGT QLPPQGRTTA HKDPSALFLS LQQLLRGKVR FLLLVEGPAL CVRRTLPTTA VPSRTSQLLT LNKF
- Physical form: Lyophilized from Sodium Citrate, pH 4.5.
- Reconstitution: Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a stabilizer (example 5% Trehalose) and store in working aliquots at -20°C to -80°C.
SAFETY INFORMATION
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Compare Similar Items
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biological source: rat
recombinant: expressed in E. coli
Assay: ≥98% (HPLC)≥98% (SDS-PAGE)
form: lyophilized
potency: ≤0.2 ng/mL ED50
mol wt: 18.7 kDa
packaging: pkg of 10 μg
technique(s): cell culture | mammalian: suitable
impurities: <0.1 EU/μg endotoxin, tested
color: white
biological source:
rat
recombinant:
expressed in E. coli
Assay:
≥98% (HPLC)≥98% (SDS-PAGE)
form:
lyophilized
potency:
≤0.2 ng/mL ED50
mol wt:
18.7 kDa
packaging:
pkg of 10 μg
technique(s):
cell culture | mammalian: suitable
impurities:
<0.1 EU/μg endotoxin, tested
color:
white
biological source: human
recombinant: expressed in E. coli
Assay: ≥95% (HPLC)≥95% (SDS-PAGE)
form: lyophilized
potency: ≥0.5 ng/mL
mol wt: 19.7 kDa
packaging: pkg of 25 μg
technique(s): __
impurities: <0.1 EU/μg endotoxin, tested
color: white to off-white
biological source:
human
recombinant:
expressed in E. coli
Assay:
≥95% (HPLC)≥95% (SDS-PAGE)
form:
lyophilized
potency:
≥0.5 ng/mL
mol wt:
19.7 kDa
packaging:
pkg of 25 μg
technique(s):
__
impurities:
<0.1 EU/μg endotoxin, tested
color:
white to off-white
biological source: human
recombinant: expressed in E. coli
Assay: ≥98% (HPLC)≥98% (SDS-PAGE)
form: lyophilized
potency: 10.0-25.0 ng/mL
mol wt: 18.7 kDa
packaging: pkg of 10 μg
technique(s): __
impurities: <0.1 EU/μg endotoxin, tested
color: white to off-white
biological source:
human
recombinant:
expressed in E. coli
Assay:
≥98% (HPLC)≥98% (SDS-PAGE)
form:
lyophilized
potency:
10.0-25.0 ng/mL
mol wt:
18.7 kDa
packaging:
pkg of 10 μg
technique(s):
__
impurities:
<0.1 EU/μg endotoxin, tested
color:
white to off-white
biological source: human
recombinant: expressed in E. coli
Assay: ≥98% (HPLC)≥98% (SDS-PAGE)
form: lyophilized
potency: 100-150 ng/mL
mol wt: 26.0 kDa
packaging: pkg of 20 μg
technique(s): __
impurities: <0.1 EU/μg endotoxin, tested
color: white to off-white
biological source:
human
recombinant:
expressed in E. coli
Assay:
≥98% (HPLC)≥98% (SDS-PAGE)
form:
lyophilized
potency:
100-150 ng/mL
mol wt:
26.0 kDa
packaging:
pkg of 20 μg
technique(s):
__
impurities:
<0.1 EU/μg endotoxin, tested
color:
white to off-white