SRP3272
TPO mouse
Animal-component free, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC)
Manufacturer: Sigma Aldrich
Synonym(S): MGDF, c-MPL Ligand
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 10 μG | SRP3272-10-μG | In Stock | ₹ 43,944.90 |
SRP3272 - 10 μG
In Stock
Quantity
1
Base Price: ₹ 43,944.90
GST (18%): ₹ 7,910.082
Total Price: ₹ 51,854.982
biological source
mouse
recombinant
expressed in E. coli
Assay
≥98% (HPLC)≥98% (SDS-PAGE)
form
lyophilized
potency
≥1.0 ng/mL ED50
mol wt
18.7 kDa
packaging
pkg of 10 μg
impurities
<0.1 EU/μg endotoxin, tested
color
white
UniProt accession no.
P40226
Related Products
Description
- General description: TPO (thrombopoietin) is a hematopoietic cytokine expressed in multiple tissue types. It is predominantly produced by liver and kidney and acts as a ligand for the cell surface receptor c-mpl.[1][2]
- Biochem/physiol Actions: TPO (thrombopoietin) is the key regulator of thrombopoiesis for platelet lineage. In both mice and humans, inactivation of this gene results in significant decrease in number of mature platelets produced by marrow progenitors. Transgenic mice with increased expression of this protein show progressive fibrosis and osteosclerosis of the bone marrow, as well as histological changes in kidneys, leading to mesangioproliferative glomerulopathy.[1][2]
- Physical form: Lyophilized from 10 mM Tris, pH 8.0.
- Reconstitution: Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.5-1.0 mg/mL. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.
SAFETY INFORMATION
Pictograms
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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biological source: mouse
recombinant: expressed in E. coli
Assay: ≥98% (HPLC)≥98% (SDS-PAGE)
form: lyophilized
potency: ≥1.0 ng/mL ED50
mol wt: 18.7 kDa
packaging: pkg of 10 μg
impurities: <0.1 EU/μg endotoxin, tested
color: white
UniProt accession no.: P40226
biological source:
mouse
recombinant:
expressed in E. coli
Assay:
≥98% (HPLC)≥98% (SDS-PAGE)
form:
lyophilized
potency:
≥1.0 ng/mL ED50
mol wt:
18.7 kDa
packaging:
pkg of 10 μg
impurities:
<0.1 EU/μg endotoxin, tested
color:
white
UniProt accession no.:
P40226
biological source: human
recombinant: expressed in E. coli
Assay: ≥98% (HPLC)≥98% (SDS-PAGE)
form: lyophilized
potency: 0.2-0.5 ng/mL
mol wt: 19.8 kDa
packaging: pkg of 20 μg
impurities: <0.1 EU/μg endotoxin, tested
color: white to off-white
UniProt accession no.: Q8IU54
biological source:
human
recombinant:
expressed in E. coli
Assay:
≥98% (HPLC)≥98% (SDS-PAGE)
form:
lyophilized
potency:
0.2-0.5 ng/mL
mol wt:
19.8 kDa
packaging:
pkg of 20 μg
impurities:
<0.1 EU/μg endotoxin, tested
color:
white to off-white
UniProt accession no.:
Q8IU54
biological source: human
recombinant: expressed in E. coli
Assay: ≥98% (HPLC)≥98% (SDS-PAGE)
form: lyophilized
potency: ≥1.0 ng/mL
mol wt: 12.6 kDa
packaging: pkg of 10 μg
impurities: <0.1 EU/μg endotoxin, tested
color: white to off-white
UniProt accession no.: P35225
biological source:
human
recombinant:
expressed in E. coli
Assay:
≥98% (HPLC)≥98% (SDS-PAGE)
form:
lyophilized
potency:
≥1.0 ng/mL
mol wt:
12.6 kDa
packaging:
pkg of 10 μg
impurities:
<0.1 EU/μg endotoxin, tested
color:
white to off-white
UniProt accession no.:
P35225
biological source: human
recombinant: expressed in E. coli
Assay: ≥98% (HPLC)≥98% (SDS-PAGE)
form: lyophilized
potency: ≥0.05 ng/mL ED50
mol wt: 17.9 kDa
packaging: pkg of 10 μg
impurities: <0.1 EU/μg endotoxin, tested
color: white to off-white
UniProt accession no.: O95760
biological source:
human
recombinant:
expressed in E. coli
Assay:
≥98% (HPLC)≥98% (SDS-PAGE)
form:
lyophilized
potency:
≥0.05 ng/mL ED50
mol wt:
17.9 kDa
packaging:
pkg of 10 μg
impurities:
<0.1 EU/μg endotoxin, tested
color:
white to off-white
UniProt accession no.:
O95760