Hyaluronic acid sodium salt from Streptococcus equi
bacterial glycosaminoglycan polysaccharide
Manufacturer: Sigma Aldrich
CAS Number: 9067-32-7
Synonym(S): Poly(β-glucuronic acid-[1→3]-β-N-acetylglucosamine-[1→4]), alternating
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 1 G | 53747-1-G | In Stock | ₹ 8,865.68 |
| 10 G | 53747-10-G | In Stock | ₹ 61,442.70 |
53747 - 1 G
In Stock
Quantity
1
Base Price: ₹ 8,865.68
GST (18%): ₹ 1,595.822
Total Price: ₹ 10,461.502
biological source
(Streptococcus equi)
Quality Level
200
form
powder or crystals
mol wt
~1.5-1.8 x 10E6 Da
impurities
≤1% protein
color
white
solubility
H2O: 5 mg/mL, clear, colorless
storage temp.
−20°C
SMILES string
[Na+].CC(=O)N[C@@H]1C[C@H](O)[C@@H](CO)O[C@H]1O[C@H]2[C@H](O)[C@@H](O)[C@H](O)O[C@@H]2C([O-])=O
InChI
1S/C28H44N2O23.Na/c1-5(33)29-9-18(11(35)7(3-31)47-25(9)46)49-28-17(41)15(39)20(22(53-28)24(44)45)51-26-10(30-6(2)34)19(12(36)8(4-32)48-26)50-27-16(40)13(37)14(38)21(52-27)23(42)43;/h7-22,25-28,31-32,35-41,46H,3-4H2,1-2H3,(H,29,33)(H,30,34)(H,42,43)(H,44,45);/q;+1/t7-,8-,9-,10-,11-,12-,13+,14+,15-,16-,17-,18-,19-,20+,21+,22+,25-,26+,27-,28-;/m1./s1
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Description
- General description: Hyaluronic acid (HA), a vital component of the extracellular matrix in the central nervous system, is the versatile macromolecule found in the connective tissues of all vertebrates. This supramolecular glycosaminoglycan is a polyanionic natural polymer occurring as a linear polysaccharide. It is made up of glucuronic acid and N-acetylglucosamine repeats through a β-1,4 linkage. HA is seen abundantly in the eyes, joints, and heart valves.
- Application: Hyaluronic acid sodium salt from Streptococcus equi has been used:with methacrylic anhydride for synthesizing cross-linkable methacrylated HA hydrogel (Coll-MeHA)in phosphate buffer saline (PBS) to replace the PBS bath to vary the lubricant compositionin the preparation of lubricant to study its effects on the boundary lubrication of human osteoarthritis (OA) cartilage
- Biochem/physiol Actions: Hyaluronic acid (HA), an important component of synovial fluid and articular cartilage serves as the boundary lubricant. It exhibits several physicochemical properties including biodegradability, biocompatibility, nontoxicity, and nonimmunogenicity. HA is considered a great tool for biomedical uses like drug delivery, tissue engineering, plastic surgery, ocular surgery, and osteoarthritis surgery. It participates in cushioning and lubricating the body. This powerful antioxidant can bond water to tissue.
- Other Notes: To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.
SAFETY INFORMATION
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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biological source: (Streptococcus equi)
Quality Level: 200
form: powder or crystals
mol wt: ~1.5-1.8 x 10E6 Da
impurities: ≤1% protein
color: white
solubility: H2O: 5 mg/mL, clear, colorless
storage temp.: −20°C
SMILES string: [Na+].CC(=O)N[C@@H]1C[C@H](O)[C@@H](CO)O[C@H]1O[C@H]2[C@H](O)[C@@H](O)[C@H](O)O[C@@H]2C([O-])=O
InChI: 1S/C28H44N2O23.Na/c1-5(33)29-9-18(11(35)7(3-31)47-25(9)46)49-28-17(41)15(39)20(22(53-28)24(44)45)51-26-10(30-6(2)34)19(12(36)8(4-32)48-26)50-27-16(40)13(37)14(38)21(52-27)23(42)43;/h7-22,25-28,31-32,35-41,46H,3-4H2,1-2H3,(H,29,33)(H,30,34)(H,42,43)(H,44,45);/q;+1/t7-,8-,9-,10-,11-,12-,13+,14+,15-,16-,17-,18-,19-,20+,21+,22+,25-,26+,27-,28-;/m1./s1
biological source: __
Quality Level: 100
form: __
mol wt: 448.08 g/mol
impurities: insoluble matter, passes filter test≤5% water
color: __
solubility: H2O: 0.1 M at 20 °C, clear, colorless
storage temp.: __
SMILES string: __
InChI: __
biological source: __
Quality Level: 200
form: __
mol wt: __
impurities: __
color: __
solubility: __
storage temp.: __
SMILES string: CCOCCOCCOC(C)=O
InChI: 1S/C8H16O4/c1-3-10-4-5-11-6-7-12-8(2)9/h3-7H2,1-2H3