56690

Hypericin from Hypericum perforatum

~95% (HPLC)

Manufacturer: Sigma Aldrich

CAS Number: 548-04-9

Synonym(S): 4,5,7,4′,5′,7′-Hexahydroxy-2,2′-dimethylnaphthodianthrone, Cyclo werrol, Hypericum red

Select a Size

Pack Size SKU Availability Price
1 MG 56690-1-MG In Stock ₹ 44,555.70

56690 - 1 MG

₹ 44,555.70

In Stock

Quantity

1

Base Price: ₹ 44,555.70

GST (18%): ₹ 8,020.026

Total Price: ₹ 52,575.726

Assay

~95% (HPLC)

Quality Level

100

solubility

1 M NaOH: 10 mg/mL, turbid, dark green

SMILES string

Cc1cc(O)c2C(=O)c3c(O)cc(O)c4c5c(O)cc(O)c6C(=O)c7c(O)cc(C)c8c1c2c(c34)c(c78)c56

InChI

1S/C30H16O8/c1-7-3-9(31)19-23-15(7)16-8(2)4-10(32)20-24(16)28-26-18(12(34)6-14(36)22(26)30(20)38)17-11(33)5-13(35)21(29(19)37)25(17)27(23)28/h3-6,31-36H,1-2H3

InChI key

BTXNYTINYBABQR-UHFFFAOYSA-N

Other Options

Image Product Name Manufacturer Price Range
50-200-8697
Enzo Life Sciences Hypericin (native) (1mg). CAS: 548-04-9
Enzo Life Sciences ₹ 8,757.07
PHL89226
Hypericin
Sigma Aldrich ₹ 73,415.15
00190585
Hypericin
Sigma Aldrich ₹ 66,064.98
56690
Hypericin from Hypericum perforatum
Sigma Aldrich ₹ 44,555.70
AI52288
548-04-9 | Hypericin
A2B Chem ₹ 3,850.20 - ₹ 42,095.52

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Description

  • General description: Hypericin hydrophobic is a red color pigment occurring naturally in Hypericum perforatum. Its fluorescence is measured at 600 nm.[1] It is localized in the intracellular membranes including nuclear membrane, mitochondrial membrane, Golgi apparatus, lysosomes and endoplasmic reticulum.[2]
  • Application: Hypericin from Hypericum perforatum has been used:in the broth macrodilution test and antibacterial assay against bacterial strains[3]as a medium supplement for human malignant melanoma cells for irradiation and localization studies[2]as a ligand for pregnane X receptor (PXR) and as defatting medium supplement for primary human hepatocytes culture[4]
  • Biochem/physiol Actions: Hypericin is a potent inhibitor of protein kinase C (PKC), telomerase, cytochrome P450 and reverse transcriptase.[1] It is exploited for its photosensitizing functionality in photodynamic therapy (PDT) and photodynamic diagnosis (PDD) in cancer cells.[5]
  • Packaging: Bottomless glass bottle. Contents are inside inserted fused cone.

SAFETY INFORMATION

Pictograms

GHS07

Signal Word

Warning

Hazard Statements

H302

Precautionary Statements

P301 + P312 + P330

Hazard Classifications

Acute Tox. 4 Oral

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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~95% (HPLC)

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1 M NaOH: 10 mg/mL, turbid, dark green

SMILES string:
Cc1cc(O)c2C(=O)c3c(O)cc(O)c4c5c(O)cc(O)c6C(=O)c7c(O)cc(C)c8c1c2c(c34)c(c78)c56

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1S/C30H16O8/c1-7-3-9(31)19-23-15(7)16-8(2)4-10(32)20-24(16)28-26-18(12(34)6-14(36)22(26)30(20)38)17-11(33)5-13(35)21(29(19)37)25(17)27(23)28/h3-6,31-36H,1-2H3

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BTXNYTINYBABQR-UHFFFAOYSA-N

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[Fe].[CH]1[CH][CH][C]([CH]1)P([C]2[CH][CH][CH][CH]2)c3ccccc3

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1S/C16H13P.Fe/c1-2-8-14(9-3-1)17(15-10-4-5-11-15)16-12-6-7-13-16;/h1-13H;

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HKOUDNXXOXEYNZ-UHFFFAOYSA-N

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REQPQFUJGGOFQL-UHFFFAOYSA-N